Drug names to mechanisms/classes Flashcards by Autumn Brubaker

Q

Trimethoprim

A

inhibits DNA replication by inhibiting dihydrofolate reductase -> inhibiting folic acid synthesis

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Q

Sulfamethoxazole

A

Inhibits DNA replication by inhibiting folic acid synthesis

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Q

Penicillins

A

inhibit penicillinase -> peptidoglycan cross linking in bacterial cell walls

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Q

Cephalosporins

A

inhibit penicillinase -> peptidoglycan cross linking in bacterial cell walls

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Q

Carbapenems

A

inhibit penicillinase -> peptidoglycan cross linking in bacterial cell walls

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Q

Aztreonam

A

inhibit penicillinase -> peptidoglycan cross linking in bacterial cell walls

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Q

Vancomycin

A

inhibits D-ala-D-ala peptidoglycan synthesis in bacterial cell walls

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Q

gentamicin

A

aminoglycoside - inhibits 30s subunit of bacterial ribosomes

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Q

Neomycin

A

aminoglycoside - inhibits 30s subunit of bacterial ribosomes

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Q

Tobramycin

A

aminoglycoside - inhibits 30s subunit of bacterial ribosomes

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Q

Clindamycin

A

inhibits 50s subunit of bacterial ribosomes

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Q

Chloramphenicol

A

inhibits 50s subunit of bacterial ribosomes

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Q

Erythromycin

A

inhibits 50s subunit of bacterial ribosomes

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Q

Azithromycin

A

inhibits 50s subunit of bacterial ribosomes

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Q

Clarithromycin

A

inhibits 50s subunit of bacterial ribosomes

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Q

Linezolid

A

inhibits 50s subunit of bacterial ribosomes

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Q

Ciprofloxacin

A

Fluoroquinolone - inhibit topoisomerase II and IV (DNA gyrase) to inhibit DNA replication

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Q

Levofloxacin

A

Fluoroquinolone - inhibit topoisomerase II and IV (DNA gyrase) to inhibit DNA replication

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Q

Moxifloxacin

A

Fluoroquinolone - inhibit topoisomerase II and IV (DNA gyrase) to inhibit DNA replication

Q

Gemifloxacin

A

Fluoroquinolone - inhibit topoisomerase II and IV (DNA gyrase) to inhibit DNA replication

Q

Disopyramide

A

IA sodium channel blocker - lengthens action potential

Q

quinidine

A

IA sodium channel blocker - lengthens action potential

Q

procainamide

A

IA sodium channel blocker - lengthens action potential

Q

Mexiletine

A

IB sodium channel blocker - shortens action potential

Q

Lidocaine

A

IB sodium channel blocker - shortens action potential

Q

Tocainide

A

IB sodium channel blocker - shortens action potential

Q

Flecainide

A

IC sodium channel blocker - no change to action potential

Q

Propafenone

A

IC sodium channel blocker - no change to action potential

Q

Amiodarone

A

Class III K+ channel blocker

Q

Diltiazem

A

Class IV CCB

Q

Verapamil

A

Class IV CCB

Q

Albuterol

A

Rapid acting beta two agonist - Relax airway smooth muscle

Side effects - Tachycardia

Q

Salmeterol

A

Long-acting Beta two agonist–Relax airways with muscle, gradual onset
Side effects - Tachycardia

Q

Formeterol

A

Long-acting Beta two agonist–Relax airways with muscle, gradual onset
Side effects - Tachycardia

Q

Beclomethasone

A

inhaled corticosteroids - Decrease airway inflammation

Side effects - oral candidiasis

Q

Flunisolide

A

inhaled corticosteroids - Decrease airway inflammation

Side effects - oral candidiasis

Q

Budesonide

A

inhaled corticosteroids - Decrease airway inflammation

Side effects - oral candidiasis

Q

Fluticasone

A

inhaled corticosteroids - Decrease airway inflammation

Side effects - oral candidiasis

Q

Montelukast

A

Leukotriene inhibitor - Decreased airway inflammation, used in the allergic rhinitis

Q

Zilueton

A

Leukotriene inhibitor - Decreased airway inflammation, used in the allergic rhinitis

Q

Zafirlukast

A

Leukotriene inhibitor - Decreased airway inflammation, used in the allergic rhinitis

Q

Cromolyn

A

Mast cell stabilizers - Decreased airway inflammation, Multiple daily dosing

Q

Nedacromil

A

Mast cell stabilizers - Decreased airway inflammation, Multiple daily dosing

Q

Theophylline

A

Relax airways with muscles - Side effects of hypertension, seizure, and tachycardia

Q

Ipratropium

A

Anticholinergic agent - Relax airway muscle

Most effective for acute exacerbations