Clinical questions - Various IM Topics Flashcards
Management of angioedema associated with ACE-i
caused by accumulation of bradykinin
Stop the ACE and switch to ARB when stable
Monitor for airway compromise, intubate if needed
Antihistamines for quicker resolution - H1 (benadryl) + H2 (ranitidine)
Epi and glucocorticoids are NOT helpful, they do not lower bradykinin levels
Causes of pharyngitis
Viral: flu, EBV, common cold
Noninfectious: allergic rhinitis, post nasal drip
Bacterial: GAS, GCS, GGS Mycoplasma pneumoniae Chlamydophila pneumoniae Corynebacterium diphtheriae
Centor Criteria and treatment of Strep pharyngitis
Centor criteria:
- tonsillar exudates
- tender anterior cervical adenopathy
- fever by history
- absence of cough
3-4 of these test for strep
Abx:
PO amor or PCN V for 10 days
IM PCN G X1 dose
2nd line - cephalosporins - cephalexin
PCN all: macrolide - azithro or clarithro
If Macrolide resistant and PCN allg - Clinda
Contraindications to and side effects of phosphodiesterase -5 inhibitors
sildenafil, tadalafil (longest acting)
Contra:
Nitrates (NG, imdur) risk of severe hypotension
Caution in alpha blockers - terazosin or parazosyn for BPH due to risk of hypotension
Side effects: Flushing Headache nasal congestion Blue vision (sildenafil - blue pill)
Management of anaphylaxis
IM epi O2 +/- intubation IVF Antihistamine for itching/hives Albuterol if not fully responding to episode Monitor 8-10 hrs following tx
Vitamin deficiency associated with macrocytic anemia with hypersegmentated neutrophils
Folate (B9) or B12
Vitamin deficiency associated with swollen gums, poor wound healing, bleeding mucous membranes, spots on skin
Vit C
Vitamin deficiency associated with dermatitis, diarrhea, dementia
-Pellagra
Niacin B3
Vitamin deficiency associated with hemorrhagic disease
Vit K
Vitamin deficiency associated with neural tube defects
Folate B9
Vitamin deficiency associated with pernicious anemia
B12
Vitamin deficiency associated with kidney disease
Vit D
Vitamin deficiency associated with bitot spots, keratomalacia, xerophthalmia
vit A
Vitamin deficiency associated with cheilosis and glossitis
B vitamins - 2, 3, 9, 12
Vitamin deficiency associated with dilated cardiomyopathy, edema, polyneuropathy
Wet beriberi - Thiamin def B1