Clinical questions - OBGYN Flashcards

1
Q

What should be performed at every prenatal visit?

A
maternal weight
BP - monitor for pregnancy induced htn
assess gestational age
fetal tones after 12-13 weeks
Fetal movement
After 3rd trimester - fetal presentation (cephalic or breech)
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2
Q

Fetal age assessment at 6-8 weeks

A

bimanual exam - uterus size of lemon

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3
Q

Fetal age assessment at 8-10 weeks

A

bimanual exam - uterus size of orange

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4
Q

Fetal age assessment at 10-12 weeks

A

bimanual exam - uterus size of grapefruit

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5
Q

Fetal age assessment at 12 weeks

A

pubic symphysis

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6
Q

Fetal age assessment at 16 weeks

A

1/2 way between pubic symphysis and umbilicus

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7
Q

Fetal age assessment at 20 weeks

A

at umbilicus

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8
Q

Fetal age assessment at 20-34 weeks

A

measure from pubic symphysis to top of funds - cm approx equal to weeks gestation

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9
Q

counseling of smoking in pregnancy

A

increase risk of placental abruption, preterm birth, low birth weight, SIDS

cessation encouraged - nicotine replacement, bupropion

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10
Q

alcohol use in pregnancy

A

teratogen
fetal alcohol syndrome
abstain completely

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11
Q

Exercise in pregnancy

A

30 min per day, avoid abdominal trauma or falls

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12
Q

Travel in pregnancy

A

no airplane travel after 36 weeks, avoid prolonged immobilization due to increased risk of DVTs

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13
Q

Sexual intercourse in pregnancy

A

avoid in placenta previa

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14
Q

Fetal alcohol syndrome

A

CNS problems
Growth retardation
Facial abnormalities - short palpebral fissure, smooth philtrum, thin vermillion border

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15
Q

Leiomyoata uteri

A

benign tumors of smooth muscle of uterus - leiomyomas, fibroids
most asx
Sx:
menorrhagia - risk low Hgb, iron supplementation
Pelvic pressure

Tx:
Hormonal contraceptive to reduce bleeding but causes increased fibroid size
Endometrial ablation
Myomectomy if desire fertility
If done having kids - uterine artery embolization, hysterectomy

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16
Q

Hyperemesis gravidarum

A

Severe nausea/vomiting causing dehydration, abnormal labs, wt loss

Mgmt: admission, IVF, IV antiemetics

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17
Q

Normal N/V of pregnancy

A

resolves as pregnancy advances

Lifestyle changes - bland foods, slow eating, small frequent meals, avoid triggers

1st med: pyridoxine (B6) + doxylamine (unasom)

Benadryl or meclizine, or zofran

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18
Q

Management of ovarian cysts

A

5-10 cm can watch

>10 cm requires surgery with risk of ovarian torsion

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19
Q

During pregnancy, when is screening performed for syphilis

A

RPR or VDRL at 1st prenatal visit, if high risk beginning of 3rd trimester as well

confirm with treponema Ab tests

  • FTA-Abs
  • MHA-TP
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20
Q

During pregnancy, when is screening performed for HIV

A

1st visit, if high risk 3rd trimester

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21
Q

During pregnancy, when is triple/quadruple screening?

A

15-20 weeks

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22
Q

During pregnancy, when is screening performed for gestational diabetes

A

24-28 wks

1 hr 50 g GTT, if abnl then 3 hr 100 g GTT

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23
Q

Administration of Rh immune globulin if Rh negative

A

28 weeks, after delivery, any time risk of fetomaternal hemorrhage (miscarriage)

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24
Q

During pregnancy, when is screening performed for g/c chlamydia

A

1st visit, high risk also in 3rd trimester

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25
Q

During pregnancy, when is screening performed for GBS

A

35-37 weeks

if positive IV PCN during labor

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26
Q

Asymptomatic bacturia in pregnancy

A

outside of pregnancy- not treated
Always treat if pregnant - high risk of pyelonephritis with dilated ureters d/t pregnancy

PO abx for 3-7 days
Nitrofurantoin
Amox
Augmentin
Cephalexin
fosfomycin - one dose

Repeat UCx 1 week after abx completed

Anyone with a UCx positive after 2 cycles of abx needs suppressive tx with macrobid for remainder of pregnancy

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27
Q

Management of suspected ectopic pregnancy

A

If unstable - immediate surgery

Stable:
TVUS
Quant bhCG
-if bhCG >1500 IUP should be seen on TVUS, absence suggests ectopic pregnancy
-if less than 1500, repeat in 48-72 hrs
> If bhCG lower - failed pregnancy, follow level to 0
> if higher but not appropriately so proceed to D&C, if chorionic villi then failed IUP, if absent chorionic villi ectopic pregnancy
> If increased 66% in 48 hrs, repeat TVUS when >1500

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28
Q

Nonstress test

A

normal 2 or more accelerations in 20 minutes

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29
Q

Contraction stress test

A

give mom oxytocin and monitor for decals with contractions, sign of utter-placental insufficiency

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30
Q

Biophysical profile

A
Nonstress test
fetal breathing
fetal movement
fetal tone
amniotic fluid volume
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31
Q

Congenital syphilis infection

A
Growth restriction 
prematurity
still birth
snuffles
hutchinson teeth
saber shins
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32
Q

Management of post-menopausal bleeding

A

endometrial biopsy to r/o hyperplasia and cancer
MC cause - atrophy of endometrium
10% endometrial cancer

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33
Q

Nutritional recommendations in pregnancy

A

supplement with folate and iron
additional 300-500 kcal daily
fully cooked meats
avoid unpasteurized dairy, deli meats (risk listeriosis)
limit fish to 12 oz per week - avoid shark, swordfish, king mackerel, tile fish

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34
Q

Weight gain recommendation for pregnancy with BMI of less than 18.5

A

28-40 lbs

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35
Q

Weight gain recommendation for pregnancy with BMI of 18.5-24.9

A

25-35 lbs

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36
Q

Weight gain recommendation for pregnancy with BMI of 25-29.9

A

15-25 lbs

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37
Q

Weight gain recommendation for pregnancy with BMI of 30 or more

A

11-20 lbs

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38
Q

teratogenic agent associated with abstain cardiac anomaly

A

Lithium

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39
Q

teratogenic agent associated with clear cell adenocarcinoma of the vagina

A

diesthylstilbestrol (DES)

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40
Q

teratogenic agent associated with microcephaly, intellectual disability, smooth philtrum

A

alcohol

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41
Q

teratogenic agent associated with gray baby syndrome

A

chloramphenicol (tx of RMSF in pregnancy, meningitis tx )

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42
Q

teratogenic agent associated with phocomelia (malformation of limbs)

A

Thalidomide

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43
Q

teratogenic agent associated with craniofacial anomalies, fingernail hypoplasia, developmental delay

A

phenytoin

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44
Q

Treatment of PID

A

GC and chlamydia penetrate the protective mucus and normal flora follow - treat as a polymicrobial infection

Output:
-Ceftriaxone IM + doxy OR PO cefoxitine + probenecid + doxy

inpt:
-IV (cefoxitine or cefotetan) + PO or IV doxy
OR IV clinda + gent

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45
Q

Pregestational diabetes

A

DM before pregnancy - type 1 or 2
Risk malformations, still births
Tx:
Insulin
fetal surveillance - weekly non stress tests starting 32-34 weeks
Deliver at 38 weeks - risk of late term fetal demise

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46
Q

Gestational diabetes

A

develops during pregnancy, resolves postpartum
risk fetal macrosomia
Tx: diabetic diet +/- insulin

47
Q

Condition suggested by the following screening: high AFP

A

neural tube or abdominal wall defect, multiple gestations, MC - incorrect dating - confirm dating with u/s

48
Q

Condition suggested by the following screening: low AFP, high bhCG, low estriol, high inhibin

A

Downs Sn - down up down up if in alpha order

49
Q

Condition suggested by the following screening: low AFP, low bhCG, low estriol

A

Trisomy 18 - Edwards - all low

50
Q

Next steps in management with abnormal triple/quad sscreening

A

targeted ultrasound

amniocentesis

51
Q

Recommended screening for ovarian cancer

A

No screening recs

CA125 is only used for monitoring disease

52
Q

Which type of abortion involves bleeding before 20 weeks gestation + no passage of products of conception (POC) + closed cervice

A

threatened abortion

53
Q

Which type of abortion involves bleeding before 20 weeks + cramping + no passage of POC + open cervice

A

inevitable abortion

54
Q

Which type of abortion involves passage of some POC + open cervix

A

incomplete abortion

55
Q

Which type of abortion involves passage of all POC + closed cervix

A

complete abortion

56
Q

Which type of abortion involves fetal death before 20 weeks gestation + no passage of POC + closed cervix

A

missed abortion

57
Q

Which type of abortion involves spontaneous abortion complicated by uterine infection

A

septic abortion

58
Q

Cervical insufficiency

A

painless cervical dilation during 2nd trimester
associated with prior LEEP or other procedure
TVUS with shortened cervical length

Tx: placement of cerclage - suture

59
Q

Treatment of Graves disease in pregnancy

A

Thionamides

  • 1st trimester propyltiouracil (PTU)
  • 2nd/3rd trimester switch to methimazole

PTU has risk of liver failure which is why you switch
Methimazole - risk birth defects if used in 1st trimester - aplasia cutis - scalp defect
Both meds have risk of agranulocytosis (rare)

If can’t take thionamides -> thyroidectomy

B-blockers like atenolol or propranolol for short term sxs control - can cause fetal growth restriction

If non-pregnant radio iodine ablation - can’t in pregnancy as will also ablate fetal thyroid

60
Q

Group B Streptococcus risk and ppx

A

Risk neonatal meningitis, pneumonia, or sepsis

ppx IV PCN G intrapartum

  • anyone GBS + at 35-37 week screening
  • Tx of any GBS bacturia this pregnancy
  • Previous infant with early onset GBS infection (1st week of life)
  • Unknown screening result + 1 of the following: intrapartum fever, PROM > 18hr, or preterm labor (before 37 weeks)
61
Q

Age to start cervical cancer screening

A

21 yo regardless of age of first intercourse

62
Q

cervical cancer screening guidelines for 21-29 yo

A

q3yrs

63
Q

cervical cancer screening guidelines for 30+ yo

A

pap q3y

pap with HPV contesting q5y

64
Q

When do you stop cervical cancer screening

A

stop at age 65 if adequate screening

do not screen after TAH performed for benign reason

65
Q

Early deceleration

A

mirrors contraction - nadir at peak of contraction

head compression

66
Q

Variable deceleration

A

Abrupt, V shaped, not necessarily with contraction

umbilical cord compression

67
Q

Late deceleration

A

after peak of contraction, gradually decelerations with gradual return to baseline - U shaped

Fetal hypoxia - utter-placental insufficiency

68
Q

Sinusoidal fetal tracing

A

severe fetal anemia

69
Q

Features of preeclampsia

A

new onset HTN during second half of pregnancy 140/90 or higher
proteinuria (300 mg/24h or more) or end organ dysfunction (thrombocytopenia, AKI, elevated LFTs, pulmonary edema, cerebral or visual sxs)

70
Q

PCOS

A
oligo or amenorrhea
Hyperandrogenism -> hirsutism
polycystic ovaries on US
Infertility
obesity
insulin resistance
endometrial hyperplasia
Mgmt:
Diet and exercise - wt loss
OCPs 1st line
Metformin 2nd line
spironolactone for hirsuitism
Clomiphene to induce ovulation for infertility
71
Q

management of shoulder dystocia

A

Emergency - umbilical cord compression
Call for help - anesthesia, help with maneuvers

Suprapubic pressure
McRoberts maneuver - legs flexed against abdomen
Deliver posterior shoulder
Last resort Zavanelli maneuver -> STAT C/S

72
Q

Complications associated with pregestational (overt) DM

A
Polyhydraminos - excess amniotic fluid
Congenital malformations
- caudal regression sn - sacral agenesis
-Situs inversus
-Neural tube defects
-cardiac anomalies: transposition of the great vessels
-Preterm birth
-Macrosomia
-unexplained still birth
-after deliver - hypoglycemia, hypocalcemia
73
Q

Menopause

A

amenorrhea for more than 12 months

If less than 45 yo:
check bhCG, prolactin, TSH, FSH to r/o other causes of amenorrhea

Tx:
HRT with estrogen and progesterone with intact uterus
Never estrogen alone in intact uterus -> increased risk of endometrial cancer
-lowest dose for shortest time for sxs control

74
Q

Management of genital HSV during pregnancy

A

rare for transplacental infection
direct contact risk -> skin/eye infection, CNS infection, disseminated dz/sepsis

Tx:
Suppressive tx with acyclovir at 36 weeks
Active infection at time of labor - prodromal or lesions -> C/S

75
Q

Complete hydratiform mole

A
46XX
no fetal tissue
Vaginal bleeding, N/V, hyperemesis gravidarum
Uterus size larger than dates
bhCG markedly elevated
"Snow storm" on u/s
Risk of malignancy and choriocarcinoma

Tx: evacuation with suction curettage
Serial bhCG until zero with risk of malignancy

76
Q

Stress incontinence

A

weakening of pelvic floor especially after having kids

Symptoms with an increased pressure - cough, sneeze

Treatments:
Lifestyle modification: Weight loss, time avoiding, pelvic floor exercises, avoid alcohol and caffeine
Pessary
Surgery

77
Q

Urge incontinence

A

Detrusor muscle overactivity

Symptoms preceded with sudden urge to void

Treatment:
Lifestyle modifications
antimuscarinics: oxybutynin, darifenacin, tolterodine

78
Q

Overflow incontinence

A

Inability to avoid normally due to over distention of the bladder - obstruction, neuropathy

Continuous leakage of urine

Tx cause
intermittent catheterization

79
Q

How is HIV infection managed throughout pregnancy?

A

Screen during the first visit, and in high-risk during third trimester

Continue current ART regimen with goal for viral load as low as possible

Monitor VL
> 1000 give intrapartum IV zidovudine (AZT) + C/S delivery
less than 1000 -> SVD, no fetal scalp electrode monitoring

Infant: ppx ART, NO breastfeeding

80
Q

Palpable breast mass worked up

A
If one of the following is suspicious, need excisional biopsy:
Exam
Imaging
-diagnostic mammography
-ultrasound
Fine needle biopsy

If all of these are normal there is a 99% chance it is benign

81
Q

Management of DVT in pregnancy

A

Anticoagulate with enoxaparin or unfractionated heparin sq - no warfarin - teratogenic

Stop a/c with labor onset or 24 h before planned delivery
-resume 12 hr postpartum - warfarin ok with bridge, continue for at least 6 weeks

Avoid estrogen contraception in future

82
Q

Intrahepatic cholestasis of pregnancy

A

Pruritic, elevated bile acid levels
occurs later in pregnancy - 2nd or 3rd trimester

Tx:
ursodeoxycolic acid to increase bile flow
hydroxyzine for itching
Deliver at 37-38 weeks d/t risk of fetal demise

83
Q

Type of amenorrhea: ballet dancer with eating disorder

A

functional hypothalamic amenorrhea

84
Q

Type of amenorrhea: short stature, low-set ears, webbed neck

A

Turner syndrome - check karyotype

85
Q

Type of amenorrhea: following D&C after spontaneous abortion

A

Asherman sn - uterine scaring and adhesions

86
Q

Type of amenorrhea: cyclic pelvic pain + blue budge at introits on exam

A

imperforate hymen

87
Q

Type of amenorrhea: elevated testosterone level and no axillary or pubic hair on exam

A

androgen insensitivity sn

88
Q

Type of amenorrhea: overweight female with acne and hirsutism

A

PCOS

89
Q

Type of amenorrhea: postpartum patient with inability to breastfeed

A

Sheehan Sn - pituitary necrosis 2/2 hemorrhage

90
Q

Type of amenorrhea: patient with anosmia

A

Kallman Sn

91
Q

Type of amenorrhea: patient with galactorrhea

A

prolactinoma

92
Q

Type of amenorrhea: MC cause

A

pregnancy

93
Q

Postpartum hemorrhage

A

> 1000 mL with C/S

>500 mL with vaginal delivery

94
Q

Uterine atony and postpartum hemorrhage management

A

No contraction to stop spiral a. bleeding
Uterus big and boggy

Tx (in order)
-fundal or bimanual massage -> encourages contraction
-explore uterine cavity for retained tissue
-uterotonic agent - Oxytocin IV, methylergonovine (increase BP - avoid in HTN), Carbopost (PGF2a - contraindicated in asthma due to bronchospasm)
-IVF +/- transfusion
If bleeding continues -> surgery: uterine artery ligation vs hysterectomy

95
Q

Induction of labor

A

reasons:

  • severe pre-eclampsia
  • Chorioaminitis
  • Post term pregnancy
Agent:
Oxytocin IV -short 1/2life, can titrate dose
Prostaglandin if cervix unfavorable
-Misoprostol - PGE1, give PO or PV
-Dinoprostone PGE2 - PV or intracervical
96
Q

Next steps in management for abnormal pap with ASCUS

A

21-24 yo repeat in 1 yr

25+ yo co-test HPV, if positive -> colpo

97
Q

Next steps in management for abnormal pap with ASC-H

A

colposcopy

98
Q

Next steps in management for abnormal pap with LSIL

A

21-24 yo repeat in 1 yr
25-29 -> colpo
30+ get HPV if positive go to colposcopies, if negative repeat in 1 yr with HPV co-testing

99
Q

Next steps in management for abnormal pap with HSIL

A

21-24 -> colpo

25+ LEEP or colpo

100
Q

Risk factors and treatment for chorioamnionitis

A

ascending infection of membranes, placenta, and amniotic fluid

Risk:
PROM
Prolonged labor
multiple cervical exams
meconium fluid
internal monitors - fetal scalp electrode, IU pressure cath

Tx:
Broad spectrum abx - amp + gent

101
Q

Premature preterm rupture of membranes PPROM

A

No contractions, less than 37 wk gestation

Mgmt:
Admit to hospital
manage expectantly - most deliver within 1 week
fever, abnormal heart tracing, or other signs of infection -> deliver baby
Corticosteroids - IM betamethasone q24h x2 for fetal lung maturity
Tocolysis to allow steroids to work - indomethacin, nifedipine, magnesium

ppx abx: amp + azithro

Deliver at 34 weeks if can make it that long

102
Q

Gardnerella vaginalis (BV)

A

thin, gray-white discharge with fishy odor - coats vaginal walls
pH > 4.5
Wet mount: clue cells, Whiff test (KOH) - fishy

Tx: metronidazole or clinda

103
Q

Candida spp. vaginal discharge

A

thick, white, cottage cheese like discharge with itching
Vaginal pH 4-4.5
Wet mount: yeast forms - pseudohyphae or budding yeast

Tx: PO fluconazole or topical clotrimazole, miconazole, or nystatin

104
Q

Trichomonas vaginalis

A

Frothy, yellow-green discharge with fishy odor
Vaginal pH > 4.5
Wet mount: motile, pear shaped trichomonad

Tx: metronidazole

105
Q

Metronidazole counseling

A

avoid alcohol for at least 3 days after tx finished due to disulfiram like reaction - n/d, flushing, tachycardia, headache

106
Q

Endometritis

A

uterine tenderness with foul-smelling loch

Tx: broad spectrum IV abx - usually polymicrobial
-Gent + clinda

107
Q

Management of pre-eclampsia with severe features

A

BP 160/110 or more
End organ dysfunction: thrombocytopenia, AKI, elevated LFTs, pulmonary edema, cerebral or visual disturbances

mgmt:
BP control to prevent stroke
-IV hydralazine, IV labetalol, PO nifedipine
Seizure ppx - IV MgSO4
Delivery definitive tx
108
Q

Primary dysmenorrhea

A

painful period w/o cause
-heat, NSAIDs, combined (E&P) hormonal contraceptive

More serious:

  • GnRH agonist - leuprolide induces medical menopause
  • Sx not responding -> lap vs hysterectomy
109
Q

ddx for third trimester bleeding

A
bloody show - normal cervical change
placenta previa
vasa previa
placental abruption
uterine rupture
110
Q

Hemolytic disease of newborn

A

Rh- mom with Ab to fetus Rh+ (anti-D Ab)
in future pregnancy Ab cross placenta and attack fetal RBCs -> severe anemia and even death

Prevent with Rh IG (Rhogam, Rhophylac) at 28 weeks, after delivery, and anytime risk of fetomaternal hemorrhage - miscarriage, ectopic pregnancy

111
Q

Medications to terminate prolonged vaginal bleeding

A

High dose PO estrogen then progestin tx after bleeding stops
Combo OCP taper - high dose with 1 week taper
High dose progestin
Tranexamic acid - blocks fibrin degradation -not commonly used

112
Q

Treatment for postpartum mastitis

A

MC S. aureus
Continue breastfeeding or pump
Anti-staph PCN
I&D if abscess on U/S

113
Q

Endometriosis

A

ectopic endometrial tissue - pelvis, bladder, colon
Classic sxs: dysmenorrhea, urinary/bowel sxs

Tx:
NSAIDs
Combo OCPs
GnRH agonist - leuprolide
Progestin
Danazol
Surgery