Drug Names (Group 5 // P - T) Flashcards

1
Q

Generic – Abciximab

A

> Brand – Reopro®
Class – antiplatelets
Background – one of two key blood clot components are platelets
Pharmacology – prevents platelet aggregation
Indications – blood clots
Side Effects – excessive bleeding, easy bruising
Interactions – increase gastrointestinal bleeding risks when used with NSAIDS and aspirin

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2
Q

Generic – Albuterol

inhaler

A

> Brand – ProAir® HFA, Proventil® HFA, Ventolin® HFA
Class – inhaled beta agonists
Background – narrowed airways is one of the main issues in asthma and COPD
Pharmacology – lung airways become dilated once beta-receptors are activated for patients to breathe easier
Indications – asthma, COPD
Side Effects – tachycardia, palpitations
Interactions – certain beta-blockers (e.g. carvedilol) can oppose inhaled beta agonists effects
(Short acting)
(Inhalation only)

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3
Q

Generic – Atomexetine

A

> Brand – Strattera®
Class – stimulants
Background – poor mental focus is a major ADHD symptom
Pharmacology – stimulates the central nervous system to improve mental focus
Indications – ADHD, narcolepsy
Side Effects – insomnia, hypertension, dependency
Interactions – increases high blood pressure and cardiovascular problems from other stimulant drugs (e.g. caffeine and weight-loss)

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4
Q

Generic – Beclomethasone

A

> Brand – Qvar®
Class – inhaled corticosteroids
Background – inflammation plays a huge role in asthma and COPD
Pharmacology – blocks natural production mechanisms of inflammatory mediators, and reduces inflammation
Indications – asthma, COPD
Side Effects – oral thrush, upper respiratory infection
Interactions – increases or decreases corticosteroids activity from certain drugs
(Rinse mouth after use)

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5
Q

Generic – Benzonatate

A

> Brand – Tessalon®

> Indications – cough

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6
Q

Generic – Budesonide

A

> Brand – Pulmicort®
Class – inhaled corticosteroids
Background – inflammation plays a huge role in asthma and COPD
Pharmacology – blocks natural production mechanisms of inflammatory mediators, and reduces inflammation
Indications – asthma, COPD
Side Effects – oral thrush, upper respiratory infection
Interactions – increases or decreases corticosteroids activity from certain drugs
(Rinse mouth after use)

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7
Q

Generic – Budesonide

nasal spray

A

> Brand – Rhinocort Aqua®

> Indications – inflammation, allergies

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8
Q

Generic – Buprenorphine

A

> Brand – Subutex®
Indications – opioid addiction
(C-III)

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9
Q

Generic – Carisoprodal

A

> Brand – Soma®
Class – muscle relaxant
Background – nervous system mediates muscle contraction
Pharmacology – nerve signals interfere muscle contraction mediation
Indications – muscle spasm, pulled muscle, back pain
Side Effects – drowsiness
Interactions – increases drowsiness/sedation from other suppressed drugs (e.g. benzodiazepines, opioids, antihistamines, alcohol) that suppress the nervous activity
(C-IV Depressants)

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10
Q

Generic – Cholestyramine

A

> Brand – Questran®
Class – bile acid sequestrants
Background – thick fluid bile acid mixture comes to intestinal tract to aid fat absorption by the liver of produced cholesterol
Pharmacology – avoids produced cholesterol of bile acids to carry through the intestines and body existence by the liver of entering the bloodstream during defections
Indications – high cholesterols
Side Effects – constipation, flatulence
Interactions – too many drug interactions occur to be interfered with the absorption of many other drugs

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11
Q

Generic – Codeine

A

> Brand – Robitussin® AC, Tylenol® #3
Class – Opioids
Background – opioid receptor activation produces analgesics and sedation
Pharmacology – provides pain relief from opioid receptor activation
Indications – pain, cough
Side effects – sedation, respiratory depression, constipation, dependency
Interactions – increases sedation and respiratory depression incidences with other drugs surpassing the nervous system (e.g. benzodiazepines, alcohol)
(C-III - C-V)
(May cause drowsiness)

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12
Q

Generic – Desvenlafaxine

A

> Brand – Pristiq®
Class – serotonin-norepinephrine reputake inhibitors (SNRIs)
Background – norepinephrine plays mood and energy level roles
Pharmacology – blocking serotonin and norepinephrine reuptake
Indications – depression, eating and generalized anxiety disorders, and diabetic peripheral neuropathy
Side Effects – similar SSRIs (e.g. serotonin syndrome) effects, including cardiovascular effects (e.g. heart palpitations, hypertensions, tachycardia) of norepinephrine
Interactions – increased serotonin syndrome risks from SSRIs and TCAs drugs

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13
Q

Generic – Dofetilide

A

> Brand – Tikosyn®
Class – antiarrhythmics
Background – irregular impulse nerves traveling within the heart is caused by cardiac arrhythmias
Pharmacology – slowness and stabilizing cardiac impulse nerves
Indications – cardiac arrhythmias
Side Effects – new or worsened cardiac arrhythmias
Interactions – occur with prolong QT interval drugs that causes life threatening cardiac arrhythmias

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14
Q

Generic – Doxepin

A

> Brand – Sinequan®
Class – tricyclic antidepressants (TCAs)
Background – both serotonin and norepinephrine are associated to mood and energy levels
Pharmacology – blocks serotonin and norepinephrine reuptake
Indications – depression, eating and generalized anxiety disorder, diabetic peripheral neuropathy
Side Effects – tachycardia, heart palpitations, hypertension, dry mouth, weight gain, reduce sex drive, serotonin syndrome
Interactions – increases serotonin syndrome with other increased serotonin activity drugs (e.g. SSRIs, SNRIs)

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15
Q

Generic – Flecainide

A

> Brand – Tambocor®
Class – antiarrhythmics
Background – irregular impulse nerves traveling within the heart is caused by cardiac arrhythmias
Pharmacology – slowness and stabilizing cardiac impulse nerves
Indications – cardiac arrhythmias
Side Effects – new or worsened cardiac arrhythmias
Interactions – occur with prolong QT interval drugs that causes life threatening cardiac arrhythmias

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16
Q

Generic – Fluoxetine

A

> Brand – Prozac®
Class – selective serotonin reuptake inhibitors (SSRIs)
Background – neurotransmitters of depression, behavior, eating, and nausea/vomiting are called serotonins, and must be in a synaptic cleft long enough to exert effect, and is removed afterwards
Pharmacology – allows serotonin to remain in the synaptic cleft
Indications – depression, behavior and eating disorders
Side Effects – agitation, confusion, hallucinations, body weight, nausea, pressured speech, tremor, rigidity, diarrhea, fever, sweating, flushing, seizures, and serotonin syndrome
Interactions – increases bleeding from NSAIDS, anticoagulants, and/or antiplatelets, and also serotonin syndrome from drugs (e.g. SNRI, TCAs)
[Chemical name: 5-hydroxytryptamine (5-HT)]

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17
Q

Generic – Guaifenesin

A

> Brand – Robitussin®
Class – cough and cold medications
Indications – expectorant (specific use)
(OTC)

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18
Q

Generic – Levothyroxine

A

> Brand – Synthroid®

> Indications – hypothyroidism

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19
Q

Generic – Medroxyprogesterone

A

> Brand – Provera®

> Indications – irregular menstrual bleeding

20
Q

Generic – Metaxalone

A

> Brand – Skelaxin®
Class – muscle relaxant
Background – nervous system mediates muscle contraction
Pharmacology – nerve signals interfere muscle contraction mediation
Indications – muscle spasm, pulled muscle, back pain
Side Effects – drowsiness
Interactions – increases drowsiness/sedation from other suppressed drugs (e.g. benzodiazepines, opioids, antihistamines, alcohol) that suppress the nervous activity

21
Q

Generic – Methocarbamol

A

> Brand – Robaxin®
Class – muscle relaxant
Background – nervous system mediates muscle contraction
Pharmacology – nerve signals interfere muscle contraction mediation
Indications – muscle spasm, pulled muscle, back pain
Side Effects – drowsiness
Interactions – increases drowsiness/sedation from other suppressed drugs (e.g. benzodiazepines, opioids, antihistamines, alcohol) that suppress the nervous activity

22
Q

Generic – Methylphenidate

A

> Brand – Ritalin®
Class – stimulants
Background – poor mental focus is a major ADHD symptom
Pharmacology – stimulates the central nervous system to improve mental focus
Indications – ADHD, narcolepsy
Side Effects – insomnia, hypertension, dependency
Interactions – increases high blood pressure and cardiovascular problems from other stimulant drugs (e.g. caffeine and weight-loss)
(C-II)

23
Q

Generic – Metoclopramide

A

> Brand – Reglan®

> Indications – GERD, heartburn

24
Q

Generic – Milnacipran

A

> Brand – Savella®
Class – serotonin-norepinephrine reputake inhibitors (SNRIs)
Background – norepinephrine plays mood and energy level roles
Pharmacology – blocking serotonin and norepinephrine reuptake
Indications – depression, eating and generalized anxiety disorders, and diabetic peripheral neuropathy
Side Effects – similar SSRIs (e.g. serotonin syndrome) effects, including cardiovascular effects (e.g. heart palpitations, hypertensions, tachycardia) of norepinephrine
Interactions – increased serotonin syndrome risks from SSRIs and TCAs drugs

25
Generic -- Mirtazapine
> Brand -- Remeron® | > Indications -- depression
26
Generic -- Modafinil
> Brand -- Provigil® > Indications -- narcolepsy, fatigue (C-IV stimulant)
27
Generic -- Montelukast
> Brand -- Singulair® | > indications -- asthma
28
Generic -- Morphine | IR
> Brand -- Roxanol® > Class -- Opioids > Background -- opioid receptor activation produces analgesics and sedation > Pharmacology -- provides pain relief from opioid receptor activation > Indications -- pain, cough > Side effects -- sedation, respiratory depression, constipation, dependency > Interactions -- increases sedation and respiratory depression incidences with other drugs surpassing the nervous system (e.g. benzodiazepines, alcohol) (C-II) (May cause drowsiness)
29
Generic -- Nabumetone
> Brand -- Relafen® > Class -- non-steroidal anti-inflammatory drugs (NSAIDs) > Background -- inflammation commonly causes pain, and prostaglandins are produced naturally within the body when mediated > Pharmacology -- blocks prostaglandins production of the cyclooxygenase (COX) enzyme responsibility > Indications -- pain, inflammation, fever > Side Effects -- nausea and vomiting, stomach ulcers, renal impairment > Interactions -- increased bleeding (especially gastrointestinal bleeding) with other anticoagulant and/or antiplatelet drugs (Rx only) (Take with food)
30
Generic -- Nifedipine
> Brand -- Procardia® > Class -- calcium channel blockers (CCBs) > Background -- effective calcium contraction comes from heart and blood line vessels of muscle tissue forms > Pharmacology -- lesser heart beats and more blood vessel relaxations to decrease blood pressure by reduced calcium to cardiac and vascular muscle cells > Indications -- hypertension, angina > Side effects -- fatigue, edema > Interactions -- increases hypotension risks with other lower blood pressure drugs
31
Generic -- Nisoldipine
> Brand -- Sular® > Class -- calcium channel blockers (CCBs) > Background -- effective calcium contraction comes from heart and blood line vessels of muscle tissue forms > Pharmacology -- lesser heart beats and more blood vessel relaxations to decrease blood pressure by reduced calcium to cardiac and vascular muscle cells > Indications -- hypertension, angina > Side effects -- fatigue, edema > Interactions -- increases hypotension risks with other lower blood pressure drugs
32
Generic -- Oxycodone | IR
> Brand -- Roxicodone® > Class -- Opioids > Background -- opioid receptor activation produces analgesics and sedation > Pharmacology -- provides pain relief from opioid receptor activation > Indications -- pain, cough > Side effects -- sedation, respiratory depression, constipation, dependency > Interactions -- increases sedation and respiratory depression incidences with other drugs surpassing the nervous system (e.g. benzodiazepines, alcohol) (C-II) (May cause drowsiness)
33
Generic -- Propafenone
> Brand -- Rythmol® > Class -- antiarrhythmics > Background -- irregular impulse nerves traveling within the heart is caused by cardiac arrhythmias > Pharmacology -- slowness and stabilizing cardiac impulse nerves > Indications -- cardiac arrhythmias > Side Effects -- new or worsened cardiac arrhythmias > Interactions -- occur with prolong QT interval drugs that causes life threatening cardiac arrhythmias
34
Generic -- Pseudoephedrine
> Brand -- Sudafed® > Class -- cough and cold medications > Indications -- decongestant (specific use) (OTC)
35
Generic -- Quetiapine
> Brand -- Seroquel® | > Indications -- psychiatric disorders
36
Generic -- Quinidine
> Brand -- Quinalan® > Class -- antiarrhythmics > Background -- irregular impulse nerves traveling within the heart is caused by cardiac arrhythmias > Pharmacology -- slowness and stabilizing cardiac impulse nerves > Indications -- cardiac arrhythmias > Side Effects -- new or worsened cardiac arrhythmias > Interactions -- occur with prolong QT interval drugs that causes life threatening cardiac arrhythmias
37
Generic -- Risperidone
> Brand -- Risperdal® | > Indications -- psychiatric disorders
38
Generic -- Ropinirole
> Brand -- Requip® | > Indications -- parkinson's disease
39
Generic -- Salmeterol | diskus//inhaler
> Brand -- Serevent® > Class -- inhaled beta agonists > Background -- narrowed airways is one of the main issues in asthma and COPD > Pharmacology -- lung airways become dilated once beta-receptors are activated for patients to breathe easier > Indications -- asthma, COPD > Side Effects -- tachycardia, palpitations > Interactions -- certain beta-blockers (e.g. carvedilol) can oppose inhaled beta agonists effects (Long acting) (Inhalation only)
40
Generic -- Sennosides | laxatives
> Brand -- Senokot® > Indications -- constipation (OTC)
41
Generic -- Sulfamethoxazole//Trimethoprim
> Brand -- Septra® > Class -- antibiotics > Background -- bacteria and humans are living cells, but there are several structural and physiological differences between them > Pharmacology -- there are different antibiotic classes where each one exploits a difference between bacterial and human cells. > Indications -- bacterial infections > Side effects -- diarrhea > Interactions -- increases warfarin of increased bleeding, and decreases oral contraceptives effects, and impair antibiotic absorption from electrolytes within antacids and multivitamins (Finish all medication unless directed otherwise)
42
Generic -- Tiotropium | inhalation capsules
> Brand -- Spriva® HandiHaler > Class -- inhaled anticholinergics > Background -- one of the main issues with COPD is narrowed airways from acetylcholine receptor activation > Pharmacology -- blocks acetylcholine receptor activations reduces airway constriction > Indications -- COPD > Side Effects -- dry mouth, constipation > Interactions -- causes constipation from opioid drugs, and additional inhaled anticholinergic drug can worsen the constipation (Inhalation only)
43
Generic -- Tiotropium | inhaler
> Brand -- Spiriva® (Respimat) > Class -- inhaled anticholinergics > Background -- one of the main issues with COPD is narrowed airways from acetylcholine receptor activation > Pharmacology -- blocks acetylcholine receptor activations reduces airway constriction > Indications -- COPD > Side Effects -- dry mouth, constipation > Interactions -- causes constipation from opioid drugs, and additional inhaled anticholinergic drug can worsen the constipation (Inhalation only)
44
Generic -- Topiramate
> Brand -- Topamax® > Class -- antiepileptic drugs (AEDs) > Background -- abnormal hyperactive nerve functions are caused by seizures > Pharmacology -- suppressing nerve activity from various mechanisms (e.g. sodium ion channel modulation, GABA receptor stimulation, glutamate receptor antagonism) > Indications -- seizures, nerve pain, psychiatric disorders > Side Effects -- drowsiness, mental slowness, weight gain, rash, SJS (rare) > Interactions -- severe nerve system suppress when combined what other suppress nerve system drugs (e.g. benzodiazepines, opioids, alcohol)
45
Generic -- Zaleplon
> Brand -- Sonata® > Class -- sedative-hypnotics (depressants) > Background -- BNZ₁ receptor activation promotes sleep > Indications -- insomnia > Side Effects -- drowsiness, somnolence, dependency > Interactions -- increases drowsiness with other drugs that suppress nervous system activity (e.g. benzodiazepines, opioids, antihistamines, alcohol) (C-IV)