Drug List Flashcards
1
Q
Ezetimibe
A
Reduces SI uptake of cholesterol by binding NPC1L1 (LDL decreases)
2
Q
Nicotinic acid
A
Inhbits mobilization of FFAs from peripheral adipose tissues (LDL decreases)
3
Q
Fibrates
A
Bind to TF PPAR-a and upreulates transcription of LPL +apo A-1 and AA-2 and downregulates transcirption of Apo-CIII which inhibits lipolysis.
- VLDL decreases
- HDL increases