Drug List Flashcards

1
Q

Ezetimibe

A

Reduces SI uptake of cholesterol by binding NPC1L1 (LDL decreases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Nicotinic acid

A

Inhbits mobilization of FFAs from peripheral adipose tissues (LDL decreases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fibrates

A

Bind to TF PPAR-a and upreulates transcription of LPL +apo A-1 and AA-2 and downregulates transcirption of Apo-CIII which inhibits lipolysis.

  • VLDL decreases
  • HDL increases
How well did you know this?
1
Not at all
2
3
4
5
Perfectly