Drug Interactions: drug-food

Question 1

HMG-CoA Reductase Inhibitors (Statins) and Grapefruit Juice

Answer 1

increases the level of statin your blood and makes side effects more likely

• rhabdomyolysis- breakdown of muscle tissue that releases a damaging protein into the blood.

Question 2

Levodopa and Protein

Answer 2

reduce how much of the drug gets into your system and how well a dose works

• a high protein meal, less levodopa reaches the site of action- the brain

Question 3

Warfain and Foods High in Vit K

Answer 3

since Warfarin interferes with the activity of Vit K, Warfarin’s effect can be reduced if Vit K increases

• Vit K- green, leafy veggies: kale, broccoli

Question 4

Monoamine Oxidase Inhibitors (MAOI) and Foods/Drinks Rich in Tyramine

Answer 4

can cause a serious spike in blood pressure and lead to a stroke

• MAOI- tranylcypromine, phenelzine, selegiline
• Foods/Drinks - things that are smoked, aged, pickled or fermented + tofu, chocolate, bananas..