Drug for vertigo Flashcards

1
Q

two types of drugs used in vertigo

A

vestibular suppressant and betahistine

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2
Q

what is the first line drug for vertigo

A

betahistine

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3
Q

betahistine mechanism

A

act as vasodilator to increase inner-ear blood flow and cerebral flow

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4
Q

betahistine agonist to antagonist what

A

agonist H-1 and antagonist H-3

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5
Q

betahistine use in

A

acute and preventive treatment of Ménière’s disease

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6
Q

precaution and ADRs of betahistine

A

patient w peptic ulcer and asthma
ADRs : nausea and vomitting

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7
Q

what does antihistamine do (mechanism)

A

antagonist histamine 1
posses choligernic effect

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8
Q

what drug can use as motion sickness drug

A

antihistamine, anticholigernic

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9
Q

which drug caused blurred vision

A

antihistamine anticholigernic

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10
Q

anticholigernic mechanism

A

antagonist at M1 receptor

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11
Q

anticholigernic side effect

A

dry mouth, tachycardia, urinary retention, blurred vision

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12
Q

Benzodiapines drug name

A

Diazepam, Lorazepam, CLonazepam

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13
Q

Action of benzodiapines

A
  • potentiate GABA on vestibular neurons or pheripherally in vestibular end-organ
  • anxiolytic effect
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14
Q

Benzodiapine use to treat what disease and not effective in treating what

A

treat Ménière’s disease or vestibular neuritis, not effective in BPPV

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15
Q

ADRs of Benzodiapine

A

sedation and risk fall

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16
Q

Name of Ca2+ channel antagonist

A

Cinnarizine and Flunarizine

17
Q

CInnarizine and Flunarizine mechanism

A

block voltage gated calcium channel in vestibular end-organ, increase blood flow in inner ear