Drug Class: INa Channel Inhibitor Flashcards by Mats Cole | Brainscape

Q

Example of INa channel inhibitor

A

RANOLAZINE

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Q

Mode of action of INa channel inhibitor

A

Inhibits persistent or late inward Na current in myocytes

Decrease Ca2+ levels
Reduce heart wall tension

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Q

Drug interactions of INa channel inhibitors

A

do NOT use with Clarithromycin and Ketoconazole = inhibit CYP3A4
- metabolised by CYP3A4

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