Drug Class: IA, IB, IC Anti-arrhythmic Drugs Flashcards
1
Q
Examples of IA anti-arrhythmic drugs
A
QUINIDINE
PROCAINAMIDE
DISPYRAMIDE
2
Q
Mode of action of IA anti-arrhythmic drugs
A
Moderate) Na+ channel blockage
- reduce amplitude of AP
- reduce conduction velocity
↑ effective refractory period
3
Q
Side effects of IA anti-arrhythmic drugs
A
Arrhythmias
Pro-arrhythmias
4
Q
What are IA anti-arrhythmic drugs used for
A
- Narrow complex tachyarrhythmias
• A fib
• SVT - Ventricular arrhythmias
5
Q
Example of IB anti-arrhythmic drug
A
LIDOCAINE
6
Q
Mode of action of IB anti-arrhythmic drugs
A
- Weak Na+ channel blockade
- ↓ effective refractory period
7
Q
Example of IC anti-arrhythmic drugs
A
FLECAINIDE
8
Q
Mode of action of IC anti-arrhythmic drugs
A
- Strong Na+ channel blockage
- Shortens plateau phase