Drug Addiction

Question 1

United Nations Report (2015)

Answer 1

Drug Stats

Question 2

UNODC (2015)

Answer 2

187,100 drug related deaths

Question 3

Leshner(1997)

Answer 3

Addiction is compulsion

All drugs have common action on mesolimbic reward system

Question 4

Leshner (1995)

Answer 4

Begins voluntarily

Question 5

Koob and LeMoal (2008)

Answer 5

Stages of drug addiction

Question 6

Larr (1989)

Answer 6

Measured positive effect through drug self-administration

Question 7

Olds and Olds (1965)

Answer 7

ICSS activation rewards and influences motivation

Question 8

Weisse (1998)

Answer 8

Activation mesolimbic system is common in drug use

Question 9

Koob (1978)

Answer 9

DA antagonist decreases positive reinforcement properties of stimulation

Question 10

Phillips (1994)

Answer 10

Amphetamine injected into NAc decreases DA antagonist

Question 11

DiChiara (1995)

Answer 11

opiates, ehtanol and nicotine increase DA in NAc

Question 12

Caine (1995)

Answer 12

D1 antagonist blocks coacaine S-A

Question 13

Dyr and Kostowski (1995)

Answer 13

Lesions block S-A ethanol

Question 14

Hubner and Koob (1990)

Answer 14

VP lesions block motivation to work for cocaine and heroin

Question 15

Olds and Meyer (1954)

Answer 15

ICSS

Stimulation acts on reward centre