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CNS > Drug Abuse > Flashcards

Drug Abuse Flashcards

1
Q

What is the site of action of class 1 drugs?

A

GABA (GPCR)

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2
Q

What is the site of action of class 2 drugs?

A

channels

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3
Q

What is the site of action of Class 3 drugs?

A

inhibit uptake/ replaces the NT

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4
Q

What do you use to treat opiate overdose?

A

naloxone

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5
Q

What do you use to treat opiate withdrawal?

A

Clonidine
Buprenorphine (partial)
Methadone (long)

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6
Q

What is supportive care for alcohol withdrawal?

A

thiamine and dextrose

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7
Q

What can treat benzodiazepine overdose?

A

Flumazenil

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8
Q

What can treat barbiturate overdose?

A

activated charcoal and urinary alkalization

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9
Q

What do you use to treat psychomotor stimulant overdose?

A

benzodiazepines
alpha blockers
supportive care

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10
Q

What do you use to treat psychomotor stimulant withdrawal?

A

antidepressants

antipsychotics

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11
Q

What does Methadone treat?

A

Heroin addiction

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12
Q

Disulfiram MOA and what does it treat

A

Alcohol abuse

increase acetaldehyde

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13
Q

MOA and purpose of Campral

A

Treat alcohol abuse

decreases glutamine in system and reduces negative withdrawal symptoms

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14
Q

Naltrexone MOA and purpose

A

opiate antagonist

reduce pleasure of alcohol (IM injection)

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15
Q

Buproprion MOA and purpose

A

block DA and NE reuptake

  • relieves cravings for nicotine
  • start 1-2 weeks before stopping smoking
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16
Q

Chantix MOA and purpose

A

partial agonist at nicotine receptors

- decrease smoking satisfaction

CNS (7 decks)

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