Drug Absorption Flashcards
What is drug absorption
Drugs being passed to the bloodstream then to the target
Where are oral drugs absorbed
Stomach and intestines
How are oral drugs absorbed to stomach and intestine
Dissolution and disintegration
What must happen for the effects of the drug to wear off
Drug must be metabolized or excreted
What factors affect absorption of oral drugs
Physical nature
Presence of food
Gastric/intestinal ph
Gastrointestinal motility
Mesentric blood flow
Other medications
Why is liquid oral medication easy to absorb
Dissolution and disintegration is already done
What is mesentric blood flow
Blood through arteries that supply the intestines
What MUST happen before gastrointestinal absorption takes place
Dosage form MUST disintegrate
Released drug MUST dissolve in gastrointestinal fluids
How does gastrointestinal motility help in drug absorption
It allows for drug to come into contact with the surfaces of gastrointestinal tract which makes absorption easier
