DRE: Drug Combinations

Question 1

Polydrug

Answer 1

ingesting two or more drugs

Question 2

LA Field Study (1985), ___% of the suspects had two or more drugs in them

Answer 2

72

Question 3

• If alcohol is discounted, nearly half (___%) of the suspects had 2 or more other drugs in them

Answer 3

45

Question 4

National DRE database indicated approximately __% of all DRE-reported cases showed 2 or more drug categories (NHTSA/IACP DRE Database (2016))

Answer 4

36

Question 5

4 Effects of Drug Combos on Major Indicators of Impairment

Answer 5

• Null Effect - no action plus no action, equals no action
• Overlapping Effect – action plus no action, equals action
• Additive Effect – action plus action, equals greater action
• Antagonistic Effect – Action plus opposite action, equals unpredictable

Question 6

Synthetic Cannabinoids

Answer 6

generally dried plant base sprayed with a mixture of synthetic Cannabimimetic compounds

Question 7

Synthetic Cathinones

Answer 7

structurally similar to amphetamines/catecholamines and chemically related to cathinone, with subtle variations that alter chemical properties, potencies and pharmacokinetics and pharmacodynamics

Question 8

Novel Stimulants

Answer 8

substances similar to Amphetamine-type stimulants, Methamphetamine analogs, and Cocaine substitutes

Question 9

Synthetic Opioids

Answer 9

share with Morphine most of their clinical pharmacological effects, including analgesia, sedation, euphoria and risk of respiratory depression.

Question 10

Novel Tryptamine Derivatives

Answer 10

can cause visual hallucinations, alterations in sensory perception, distortion of body image, depersonalization, anxiety, and panic