Dr. Dereimer- Body cavity deve Flashcards

1
Q

what causes pentology of cantrell

A

improper fusion of the ectoderm across the midline . Failure of ventral body wall formation after lateral folding.

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2
Q

budding of organs from endroderm gut tube happens during what week

A

week 4

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3
Q

what does the proctodeum develop into

A

colon and rectum

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4
Q

what folds form the lung cavity and pericardial cavity

A

peuropericardial folds

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5
Q

where is the orgin of the phrenic nerve

A

c3-c5

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6
Q

what does the septum transversum divide

A

thorraic and diaphragm

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7
Q

what misfold causes a congenital diaphragmatic hernia

A

left exteriolateral perotenial fold

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8
Q

what part of the lungs come from the body wall

A

costodiaphragmatic recess

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9
Q

what part of the lung do you see infection first

A

the costodiaphragmatic recess

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10
Q

what nerve innervates the costodiaphragmatic recess

A

t5-t12 intercostal nerves

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11
Q

the majority of the dipragm comes from what region

A

transverse septum

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12
Q

what are the 3 elements of the abdomin

A

aorta, esophagus, inferior vena cava

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13
Q

the pleural peritoneal fold doesnt develop, what could occur?

A

congenital diaphragmatic hernia

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14
Q

what is the most common hernina

A

haital hernia

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15
Q

congenital diphragmatic hernias are related to what folds

A

posterolateral folds

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16
Q

congenital diaphragmatic hernia causes what

A

the lungs wont develop. (pulmonary hyperplasia)

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17
Q

what parts build the diaphrarm

A
  1. Septum transversum
  2. Pluroperitoneal folds
  3. Body wall
  4. Dorsal mesnetary of the espohagus

SPBD- Several parts build diaphragm

18
Q

What forms endoderm

A

epithelial lining of stomach and intestnies, parenychma of glands , liver, pancreas gall bladder.

19
Q

what forms mesoderm

A

connective tissue, stroma of glans smooth muscles , blood vessels SPLEEN

20
Q

the anus is made of what germ layer

A

ectoderms

21
Q

neural crest forms what to things

A

PNS, and enteric nervous system

22
Q

hox genes interact with

A

sonic hedge hog

23
Q

what gene is responsible foe pancreatic devlopment

A

pdx-1

24
Q

what gene is responsible for heart development

A

Nkx 2.5

25
Q

what arteries for the foregut, midgut and hindgut

A

foregut = celiac artery

midgut = superior mesentary artery

Hindgut = inferior mesentary artery

26
Q

the vitaline duct connects to

A

yolk sac

27
Q

bloackages in the esophagus can lead to

A

polyhydraminos

28
Q

what forms the greater omentum

A

dorsal mesentary

29
Q

development of liver is related to the …

A

heart. it takes a heart to make a liver!

30
Q

what gene is important for the development of the pancreas

A

PDX-1

31
Q

What makes up the main part of the pancreas

A

dorsal duct

32
Q

which bud noramally rotates in the pancreas

A

ventral bud

33
Q

what causes annular pancreas

A

the ventral buds fail to rotate

34
Q

what are the 4 key events in midgut development

A

herniation -week 6
rotation - 270deg
return to abdomen
fixation

35
Q

when does herniation take place

A

week 6

36
Q

when does return to abdomen take place

A

week 9

37
Q

in a volvuls, what does the intestines twist around

A

the superior messentary artery which consticts blood flow!

38
Q

during development does it herniate and then rotate or rotate and then herniate

A

herniate and then rotate

39
Q

what causes hirschprungs disease

A

neural crest cells failing to migrate

40
Q

failure to pass mechonium is highly associated with

A

hirshprungs disease

41
Q

when does recannalization occur

A

8th week