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Practice > Doxycycline-Immune Globulin > Flashcards

Doxycycline-Immune Globulin Flashcards

1
Q

What is the brand name of Doxycycline hyclate?

A

Vibramycin (IV and PO)

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2
Q

What is the class of Doxycycline?

A

Tetracycline antibiotic (binds 30s)

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3
Q

Indication for Doxycycline?

A

CAP (adults), CA-MRSA, VRE, Lyme Disease, malaria, animal and human bites, STDs, clostridium, anthrax (need look up uses)

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4
Q

Indication for Doxycycline powder?

A

Malignant pleural effusions

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5
Q

What is the brand name of Droperidol?

A

Inaspsine

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6
Q

What is the class of Droperidol?

A

Antipsychotic agent, antiemetic

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7
Q

Droperidol boxed warning?

A

Prolonged QT interval

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8
Q

AEs of Droperidol?

A

EPS (class effect) and anticholinergic effects (requires ECG monitoring)

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9
Q

Indication of Droperidol?

A

Pre and post operative antiemetic

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10
Q

What is the brand name of Enalipralat?

A

Vasotec IV

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11
Q

What is the class of Enalipralat?

A

IV ACE #

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12
Q

AEs of Enalipralat?

A

Increased K+ (by like 0.5), hypovolemia, poor renal function, renal artery stenosis (RAS), angioedema, cough

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13
Q

DI with Enalipralat?

A

Drugs that increase K+

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14
Q

Caution in using Enalipralat in…

A

renal dysfunction

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15
Q

Doses for Enalipralat in renal dysfunction?

A

0.625-1.25 mg q6h

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16
Q

What is the brand name of Enoxaparin?

A

Lovenox

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17
Q

What is the class of Enoxaparin?

A

LMWH

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18
Q

Enoxaparin CI with?

A

Active major bleeding, HIT, epidurals, spinals (risk of epidural hematoma and paralysis)

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19
Q

Dose adjustments for Enoxaparin in?

A

Age, renal function, indication

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20
Q

Monitoring for Enoxaparin?

A

anti-10a

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21
Q

Prophylaxis dosing of Enoxaparin for DVT/PE?

A

30-40 mg q12/24 hours

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22
Q

Treatment dosing of Enoxaparin for DVT/PE?

A

1 mg/kg q12h

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23
Q

What is the brand name of Epinephrine?

A

Adrenalin, Epi-pen

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24
Q

What is the class of Epinephrine?

A

Natural sympathomimetic catecholamine

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25
Q

MOA of Epinephrine?

A

Stimulates alpha 1,2 and beta 1,2 receptors (dose determines response)

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26
Q

Dose of Epinephrine is in?

A

mcg/kg/min

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27
Q

Strengths of Epinephrine vials available?

A

1:1,000 and 1:10,000

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28
Q

mg/mL in 1:1,000 Epinephrine?

A

1 mg in 1 mL (ampules)

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29
Q

mg/mL in 1:10,000 Epinephrine?

A

1 in 10 mL (code dosing)

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30
Q

Epipen dose

A

0.3 mg (>30 kg)

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31
Q

Epipen Jr dose

A

0.15 (<30 kg)

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32
Q

How much Epipen to carry?

A

1 dose for every 10-20 minutes travel time

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33
Q

What is the brand name of Epoetin alfa?

A

Epogen, Procrit

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34
Q

What is the class of Epoetin alfa?

A

Blood modifier (stimulates RBC production)

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35
Q

__________ must be adequate for Epoetin alfa to work?

A

Iron stores

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36
Q

BP must be under control prior to starting which drug?

A

Epoetin alfa

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37
Q

Caution using Epoetin alfa with h/o?

A

Seizures

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38
Q

Monitoring in Epoetin alfa?

A

Hb (can lead to HTN, myalgia, HA, NVD)

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39
Q

Does Epoetin alfa work for acute anemia?

A

NO (at this point you need blood)

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40
Q

How many dosage strengths does Epoetin alfa come in?

A

MANY

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41
Q

What is the brand name of Erythromycin lactobionate?

A

Erythrocin

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42
Q

What is the class of Erythromycin?

A

Macrolide antibiotic

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43
Q

DI with Erythromycin?

A

CYP substrate 2B6, 3A4 and CYP inhibitor 1A2, 3A4

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44
Q

AE of Erythromycin?

A

QT interval prolongation

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45
Q

Erythromycin vs. Azithromycin?

A

More unstable and more painful to infuse

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46
Q

Indications for Erythromycin?

A

PNA, Legionnaire’s disease, chlamydia, pertussis, atypicals, some gram +, staph, S. pneumo, N. gonorrhoeae, syphillis (look up dosing, varies by indication)

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47
Q

Must be diluted in large volume (stability) and given over 1 hour?

A

Erythromycin

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48
Q

What is the brand name of Esmolol?

A

Brevibloc

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49
Q

What is the class of Esmolol?

A

Beta 1 selective beta blocker (IV only)

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50
Q

Activity of Esmolol?

A

VERY SHORT ACTING (infusion = decreased BP, stopping = increased BP)

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51
Q

What does infusion of Esmolol require?

A

Pump

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52
Q

What is the brand name of Esomeprazole?

A

Nexium

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53
Q

What is the class of Esomeprazole?

A

PPI

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54
Q

How is IV form of Esomeprazole given?

A

IV push over 3 minutes or infused over 10-30 minutes

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55
Q

DI with Esomeprazole?

A

Decreases Clipodegrel

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56
Q

What is the brand name of Etomidate?

A

Amidate

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57
Q

What is the class of Etomidate?

A

Ultra-short acting benzylimidazole hypnotic (sedative)

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58
Q

AEs of Etomidate?

A

Pain at injection site, nausea

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59
Q

What is the brand name of Factor 7a?

A

NovoSeven

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60
Q

Indications for Factor 7a?

A

Anti-hemophilic agent, used to treat bleeding episodes, prevention of bleeding in hemophilia A and B during surgery, stop uncontrolled bleeding

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61
Q

Reconstitution of Factor 7a?

A

DO NOT RECONSTITUTE UNLESS YOU ARE GOING TO USE IT (only stable for 3 hours)

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62
Q

What is the brand name of Famotidine?

A

Pepcid

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63
Q

What is the class of Famotidine?

A

H2 blocker

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64
Q

Plus of Famotidine vs. Cimetidine?

A

Minimal drug interactions

65
Q

Dose adjust Famotidine in?

A

Renal dysfunction and age (20 mg qd vs. 20 mg BID)

66
Q

Administration of Famotidine?

A

IV push and PO

67
Q

AEs of Famotidine?

A

CNS effects (especially in elderly), GI effects

68
Q

What is the brand name of Fentanyl?

A

Sublimaze

69
Q

What is the class of Fentanyl?

A

Semisynthetic opioid analgesic (safe in morphine allergic patients)

70
Q

Watch for these effects with the use of Fentanyl?

A

Cross-reactivity, bradyarrhythmias, respiratory/CNS depression, GI

71
Q

100 mcg of Fentanyl = _______ morphine

A

10 mg

72
Q

25 mcg of Fentanyl = _________ morphine

A

2.5 mg

73
Q

AE of Fentanyl in neonates?

A

Chest wall rigidity (use Naloxone for reversal)

74
Q

Boxed warning for Fentanyl patch?

A

The patch is NOT for use in patients who have not been on chronic opioids (opioid-naive)

75
Q

Which form of Fentanyl is acceptable to use in opioid-naive patients?

A

IV

76
Q

Which form of Fentanyl is NOT acceptable to use in opioid-naive patients?

A

Patch

77
Q

What is the brand name of Filgrastim?

A

Neupogen, G-CSF

78
Q

What is the class of Filgrastim?

A

Hematopoietic growth factor (WBCs)

79
Q

Indication for Filgrastim?

A

Shortens length of time neutropenic patients will stay in hospital (esp. in chemotherapy)

80
Q

AE of Filgrastim?

A

WBC count will go too high leading to bone pain, fever, local reactions, splenomegaly

81
Q

Derived from E. Coli source?

A

Filgrastim

82
Q

Give 24 hours after chemotherapy?

A

Filgrastim

83
Q

Filgrastim CI with?

A

Certain malignancies (any with myeloid characteristics)

84
Q

Monitoring with Filgrastim?

A

WBCs to avoid “overdoing it”

85
Q

What is the brand name of Fluconazole?

A

Diflucan

86
Q

What is the class of Fluconazole?

A

Synthetic tri-azole systemic anti-fungal

87
Q

DIs with Fluconazole?

A

CYP 450

88
Q

Monitoring with Fluconazole?

A

Liver (need to look up dosing and side effects)

89
Q

Bugs Fluconazole treats?

A

Candida infections, cryptococcus (can cross into CSF due to LMW)

90
Q

IV dosing vs. Oral dosing of Fluconazole?

A

Same

91
Q

Must adjust Fluconazole in _______ dysfunction?

A

Renal

92
Q

What is the brand name of Fondaparinux sodium?

A

Arixtra

93
Q

What is the class of Fondaparinux?

A

Anti-thrombotic agent (binds AT-3), similar in effect/use to LMWH

94
Q

Renal dosing of Fondaparinux?

A

Caution CrCl <50 kg

95
Q

Indication of Fondaparinux?

A

Prophylaxis of DVT and PE

96
Q

Caution with Fondaparinux use in?

A

Epidural, spinal, HIT

97
Q

What is the brand name of Foscarnet?

A

Foscavir

98
Q

Indication for Foscarnet?

A

Acyclovir-resistant HSV and Gancyclovir-resistant CMV

99
Q

AEs of Foscarnet?

A

LOTS of side effects

100
Q

Dose of Foscarnet is VERY dependent on?

A

Renal function

101
Q

Infusion rate of Foscarnet?

A

1 mg/kg/min

102
Q

What is the brand name of Fosphenytoin?

A

Cerebyx

103
Q

What is the class of Fosphenytoin?

A

Pro-drug of phenytoin (anti-convulsant)

104
Q

Is it safe to use Fosphenytoin in Phenytoin allergies?

A

NO

105
Q

Indication of Fosphenytoin?

A

Status epilepticus and for prophylaxis

106
Q

Dosage forms of Fosphenytoin?

A

IM or more rapid IV

107
Q

Dose of Fosphenytoin vs. Phenytoin?

A

Same (1:1)

108
Q

What is the brand name of Furosemide?

A

Lasix

109
Q

What is the class of Furosemide?

A

Loop diuretic

110
Q

DI with Furosemide?

A

Any drug with K effects, digoxin, decreases clearance of lithium

111
Q

Caution with use of Furosemide in?

A

Anuria, worsening renal function, SULFA allergy

112
Q

Monitoring with Furosemide?

A

Hypotension

Hypo K, Mg, Na, etc.

113
Q

What is the brand name of Ganciclovir?

A

Cytovene

114
Q

What is the class of Ganciclovir?

A

Antiviral agent

115
Q

DI with Ganciclovir?

A

Imipenem (caution with nephrotoxics)

116
Q

Caution with use of Ganciclovir in?

A

Poor hydration, pre-existing neutropenia

117
Q

AEs of Ganciclovir?

A

Bone marrow supression (common), fever, edema, HA, nausea, myalgia

118
Q

Indication of Ganciclovir?

A

Treatment and prophylaxis of CMV

119
Q

Teratogenic caution with Ganciclovir?

A

Must use contraceptive precautions for 90 days after therapy, best to give to men or women who have had hysterectomy, caution with handling

120
Q

What is the brand name of Gentamycin?

A

Garamycin

121
Q

What is the class of Gentamicin?

A

Aminoglycoside

122
Q

DI with Gentamicin?

A

Neuromuscular blockers, other nephrotoxins

123
Q

AEs of Gentamicin?

A

Nephrotoxic and ototoxic (vestibular and cochlear)

124
Q

Bugs Gentmicin treats?

A

Gram - aerobes

125
Q

Monitoring for Gentamicin?

A

Renal function, serum drug monitoring

126
Q

What is the brand name of Granisetron?

A

Kytril

127
Q

What is the class of Granisetron?

A

Antiemetic (5HT3 #)

128
Q

Indication of Granisetron?

A

CINV, PONV

129
Q

Administration of Granisetron?

A

IV push, transdermal

130
Q

What is the brand name of Haloperidol?

A

Haldol

131
Q

AEs of Haloperidol?

A

Hypotension, tardive dyskinesia, EPS reactions, neuroletpic malignant syndrome

132
Q

Indications for Haloperidol?

A

Psychosis, sedation (without cardiac AEs), schizophrenia

133
Q

Haloperidol Decanoate Salt for _____ use only?

A

IM (other forms can be slow IV)

134
Q

What is the class of Heparin?

A

Anticoagulant/anti-thrombotic agent (prophylaxis of thrombosis, treatment, and catheter patency)

135
Q

AEs of Heparin?

A

HIT and uncontrolled bleeding

136
Q

Monitoring of Heparin?

A

Doses in units/kg then adjusted with aPTT monitoring

137
Q

How many different strengths of Heparin are there?

A

LOTS (use caution)

138
Q

What is the class of Hydralazine?

A

Systemic vasodilator antihypertensive

139
Q

Hydralazine is CI with?

A

SLE, mitral valve rheumatic heart failure

140
Q

Indications of Hydralazine?

A

HTN, adjunctive for CHF, preeclampsia

141
Q

What is the brand name of Hydrocortisone Sodium Succinate?

A

Solu-Cortef

142
Q

What is the class of Hydrocortisone?

A

Glucocorticoid anti-inflammatory

143
Q

Caution with use of Hydrocortisone in?

A

infection, PUD, hypothyroid, DM, cirrhosis, hypernatremia

144
Q

Indications for Hydrocortisone?

A

Adrenal insufficiency, asthma, shock

145
Q

Hydrocortisone DOC for?

A

IV replacement in adrenocortical insufficiency

146
Q

What is the brand name of Hydromorphone?

A

Dilaudid

147
Q

What is the class of Hydromorphone?

A

Semi-synthetic opioid analgesic

148
Q

AEs of Hydromorphone?

A

Respiratory and CNS depression, GI, urinary retention

149
Q

Indications of Hydromorphone?

A

Moderate-severe pain, antitussive

150
Q

Hydromorphone 1.5 mg = _____ Morphine

A

10 mg

151
Q

Hydromorphone 1 mg = _____ Morphine

A

7 mg (homerun:touchdown)

152
Q

What is the brand name of Immune Globulin?

A

IVIG

153
Q

What is the class of Immune Globulin?

A

Immune globulin replacement

154
Q

DI with Immune Globulin?

A

Live virus vaccines

155
Q

Caution with use of Immune Globulin in?

A

IgA deficiency, renal dysfunction, products with sucrose

156
Q

AEs of Immune Globulin?

A

Infusion reactions (common) so ramp up infusion slowly (give a little, wait 30 min, repeat)

157
Q

Indications of Immune Globulin?

A

Primary immune deficiencies, Kawasaki’s disease, ITP

158
Q

Dosing of Immune Globulin?

A

Read package insert before use or changing products

Practice (5 decks)

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