Doxycycline-Immune Globulin Flashcards
1
Q
What is the brand name of Doxycycline hyclate?
A
Vibramycin (IV and PO)
2
Q
What is the class of Doxycycline?
A
Tetracycline antibiotic (binds 30s)
3
Q
Indication for Doxycycline?
A
CAP (adults), CA-MRSA, VRE, Lyme Disease, malaria, animal and human bites, STDs, clostridium, anthrax (need look up uses)
4
Q
Indication for Doxycycline powder?
A
Malignant pleural effusions
5
Q
What is the brand name of Droperidol?
A
Inaspsine
6
Q
What is the class of Droperidol?
A
Antipsychotic agent, antiemetic
7
Q
Droperidol boxed warning?
A
Prolonged QT interval
8
Q
AEs of Droperidol?
A
EPS (class effect) and anticholinergic effects (requires ECG monitoring)
9
Q
Indication of Droperidol?
A
Pre and post operative antiemetic
10
Q
What is the brand name of Enalipralat?
A
Vasotec IV
11
Q
What is the class of Enalipralat?
A
IV ACE #
12
Q
AEs of Enalipralat?
A
Increased K+ (by like 0.5), hypovolemia, poor renal function, renal artery stenosis (RAS), angioedema, cough
13
Q
DI with Enalipralat?
A
Drugs that increase K+
14
Q
Caution in using Enalipralat in…
A
renal dysfunction
15
Q
Doses for Enalipralat in renal dysfunction?
A
0.625-1.25 mg q6h
16
Q
What is the brand name of Enoxaparin?
A
Lovenox
17
Q
What is the class of Enoxaparin?
A
LMWH
18
Q
Enoxaparin CI with?
A
Active major bleeding, HIT, epidurals, spinals (risk of epidural hematoma and paralysis)
19
Q
Dose adjustments for Enoxaparin in?
A
Age, renal function, indication
20
Q
Monitoring for Enoxaparin?
A
anti-10a
21
Q
Prophylaxis dosing of Enoxaparin for DVT/PE?
A
30-40 mg q12/24 hours
22
Q
Treatment dosing of Enoxaparin for DVT/PE?
A
1 mg/kg q12h
23
Q
What is the brand name of Epinephrine?
A
Adrenalin, Epi-pen
24
Q
What is the class of Epinephrine?
A
Natural sympathomimetic catecholamine
25
MOA of Epinephrine?
Stimulates alpha 1,2 and beta 1,2 receptors (dose determines response)
26
Dose of Epinephrine is in?
mcg/kg/min
27
Strengths of Epinephrine vials available?
1:1,000 and 1:10,000
28
mg/mL in 1:1,000 Epinephrine?
1 mg in 1 mL (ampules)
29
mg/mL in 1:10,000 Epinephrine?
1 in 10 mL (code dosing)
30
Epipen dose
0.3 mg (>30 kg)
31
Epipen Jr dose
0.15 (<30 kg)
32
How much Epipen to carry?
1 dose for every 10-20 minutes travel time
33
What is the brand name of Epoetin alfa?
Epogen, Procrit
34
What is the class of Epoetin alfa?
Blood modifier (stimulates RBC production)
35
__________ must be adequate for Epoetin alfa to work?
Iron stores
36
BP must be under control prior to starting which drug?
Epoetin alfa
37
Caution using Epoetin alfa with h/o?
Seizures
38
Monitoring in Epoetin alfa?
Hb (can lead to HTN, myalgia, HA, NVD)
39
Does Epoetin alfa work for acute anemia?
NO (at this point you need blood)
40
How many dosage strengths does Epoetin alfa come in?
MANY
41
What is the brand name of Erythromycin lactobionate?
Erythrocin
42
What is the class of Erythromycin?
Macrolide antibiotic
43
DI with Erythromycin?
CYP substrate 2B6, 3A4 and CYP inhibitor 1A2, 3A4
44
AE of Erythromycin?
QT interval prolongation
45
Erythromycin vs. Azithromycin?
More unstable and more painful to infuse
46
Indications for Erythromycin?
PNA, Legionnaire's disease, chlamydia, pertussis, atypicals, some gram +, staph, S. pneumo, N. gonorrhoeae, syphillis (look up dosing, varies by indication)
47
Must be diluted in large volume (stability) and given over 1 hour?
Erythromycin
48
What is the brand name of Esmolol?
Brevibloc
49
What is the class of Esmolol?
Beta 1 selective beta blocker (IV only)
50
Activity of Esmolol?
VERY SHORT ACTING (infusion = decreased BP, stopping = increased BP)
51
What does infusion of Esmolol require?
Pump
52
What is the brand name of Esomeprazole?
Nexium
53
What is the class of Esomeprazole?
PPI
54
How is IV form of Esomeprazole given?
IV push over 3 minutes or infused over 10-30 minutes
55
DI with Esomeprazole?
Decreases Clipodegrel
56
What is the brand name of Etomidate?
Amidate
57
What is the class of Etomidate?
Ultra-short acting benzylimidazole hypnotic (sedative)
58
AEs of Etomidate?
Pain at injection site, nausea
59
What is the brand name of Factor 7a?
NovoSeven
60
Indications for Factor 7a?
Anti-hemophilic agent, used to treat bleeding episodes, prevention of bleeding in hemophilia A and B during surgery, stop uncontrolled bleeding
61
Reconstitution of Factor 7a?
DO NOT RECONSTITUTE UNLESS YOU ARE GOING TO USE IT (only stable for 3 hours)
62
What is the brand name of Famotidine?
Pepcid
63
What is the class of Famotidine?
H2 blocker
64
Plus of Famotidine vs. Cimetidine?
Minimal drug interactions
65
Dose adjust Famotidine in?
Renal dysfunction and age (20 mg qd vs. 20 mg BID)
66
Administration of Famotidine?
IV push and PO
67
AEs of Famotidine?
CNS effects (especially in elderly), GI effects
68
What is the brand name of Fentanyl?
Sublimaze
69
What is the class of Fentanyl?
Semisynthetic opioid analgesic (safe in morphine allergic patients)
70
Watch for these effects with the use of Fentanyl?
Cross-reactivity, bradyarrhythmias, respiratory/CNS depression, GI
71
100 mcg of Fentanyl = _______ morphine
10 mg
72
25 mcg of Fentanyl = _________ morphine
2.5 mg
73
AE of Fentanyl in neonates?
Chest wall rigidity (use Naloxone for reversal)
74
Boxed warning for Fentanyl patch?
The patch is NOT for use in patients who have not been on chronic opioids (opioid-naive)
75
Which form of Fentanyl is acceptable to use in opioid-naive patients?
IV
76
Which form of Fentanyl is NOT acceptable to use in opioid-naive patients?
Patch
77
What is the brand name of Filgrastim?
Neupogen, G-CSF
78
What is the class of Filgrastim?
Hematopoietic growth factor (WBCs)
79
Indication for Filgrastim?
Shortens length of time neutropenic patients will stay in hospital (esp. in chemotherapy)
80
AE of Filgrastim?
WBC count will go too high leading to bone pain, fever, local reactions, splenomegaly
81
Derived from E. Coli source?
Filgrastim
82
Give 24 hours after chemotherapy?
Filgrastim
83
Filgrastim CI with?
Certain malignancies (any with myeloid characteristics)
84
Monitoring with Filgrastim?
WBCs to avoid "overdoing it"
85
What is the brand name of Fluconazole?
Diflucan
86
What is the class of Fluconazole?
Synthetic tri-azole systemic anti-fungal
87
DIs with Fluconazole?
CYP 450
88
Monitoring with Fluconazole?
Liver (need to look up dosing and side effects)
89
Bugs Fluconazole treats?
Candida infections, cryptococcus (can cross into CSF due to LMW)
90
IV dosing vs. Oral dosing of Fluconazole?
Same
91
Must adjust Fluconazole in _______ dysfunction?
Renal
92
What is the brand name of Fondaparinux sodium?
Arixtra
93
What is the class of Fondaparinux?
Anti-thrombotic agent (binds AT-3), similar in effect/use to LMWH
94
Renal dosing of Fondaparinux?
Caution CrCl <50 kg
95
Indication of Fondaparinux?
Prophylaxis of DVT and PE
96
Caution with Fondaparinux use in?
Epidural, spinal, HIT
97
What is the brand name of Foscarnet?
Foscavir
98
Indication for Foscarnet?
Acyclovir-resistant HSV and Gancyclovir-resistant CMV
99
AEs of Foscarnet?
LOTS of side effects
100
Dose of Foscarnet is VERY dependent on?
Renal function
101
Infusion rate of Foscarnet?
1 mg/kg/min
102
What is the brand name of Fosphenytoin?
Cerebyx
103
What is the class of Fosphenytoin?
Pro-drug of phenytoin (anti-convulsant)
104
Is it safe to use Fosphenytoin in Phenytoin allergies?
NO
105
Indication of Fosphenytoin?
Status epilepticus and for prophylaxis
106
Dosage forms of Fosphenytoin?
IM or more rapid IV
107
Dose of Fosphenytoin vs. Phenytoin?
Same (1:1)
108
What is the brand name of Furosemide?
Lasix
109
What is the class of Furosemide?
Loop diuretic
110
DI with Furosemide?
Any drug with K effects, digoxin, decreases clearance of lithium
111
Caution with use of Furosemide in?
Anuria, worsening renal function, SULFA allergy
112
Monitoring with Furosemide?
Hypotension
| Hypo K, Mg, Na, etc.
113
What is the brand name of Ganciclovir?
Cytovene
114
What is the class of Ganciclovir?
Antiviral agent
115
DI with Ganciclovir?
Imipenem (caution with nephrotoxics)
116
Caution with use of Ganciclovir in?
Poor hydration, pre-existing neutropenia
117
AEs of Ganciclovir?
Bone marrow supression (common), fever, edema, HA, nausea, myalgia
118
Indication of Ganciclovir?
Treatment and prophylaxis of CMV
119
Teratogenic caution with Ganciclovir?
Must use contraceptive precautions for 90 days after therapy, best to give to men or women who have had hysterectomy, caution with handling
120
What is the brand name of Gentamycin?
Garamycin
121
What is the class of Gentamicin?
Aminoglycoside
122
DI with Gentamicin?
Neuromuscular blockers, other nephrotoxins
123
AEs of Gentamicin?
Nephrotoxic and ototoxic (vestibular and cochlear)
124
Bugs Gentmicin treats?
Gram - aerobes
125
Monitoring for Gentamicin?
Renal function, serum drug monitoring
126
What is the brand name of Granisetron?
Kytril
127
What is the class of Granisetron?
Antiemetic (5HT3 #)
128
Indication of Granisetron?
CINV, PONV
129
Administration of Granisetron?
IV push, transdermal
130
What is the brand name of Haloperidol?
Haldol
131
AEs of Haloperidol?
Hypotension, tardive dyskinesia, EPS reactions, neuroletpic malignant syndrome
132
Indications for Haloperidol?
Psychosis, sedation (without cardiac AEs), schizophrenia
133
Haloperidol Decanoate Salt for _____ use only?
IM (other forms can be slow IV)
134
What is the class of Heparin?
Anticoagulant/anti-thrombotic agent (prophylaxis of thrombosis, treatment, and catheter patency)
135
AEs of Heparin?
HIT and uncontrolled bleeding
136
Monitoring of Heparin?
Doses in units/kg then adjusted with aPTT monitoring
137
How many different strengths of Heparin are there?
LOTS (use caution)
138
What is the class of Hydralazine?
Systemic vasodilator antihypertensive
139
Hydralazine is CI with?
SLE, mitral valve rheumatic heart failure
140
Indications of Hydralazine?
HTN, adjunctive for CHF, preeclampsia
141
What is the brand name of Hydrocortisone Sodium Succinate?
Solu-Cortef
142
What is the class of Hydrocortisone?
Glucocorticoid anti-inflammatory
143
Caution with use of Hydrocortisone in?
infection, PUD, hypothyroid, DM, cirrhosis, hypernatremia
144
Indications for Hydrocortisone?
Adrenal insufficiency, asthma, shock
145
Hydrocortisone DOC for?
IV replacement in adrenocortical insufficiency
146
What is the brand name of Hydromorphone?
Dilaudid
147
What is the class of Hydromorphone?
Semi-synthetic opioid analgesic
148
AEs of Hydromorphone?
Respiratory and CNS depression, GI, urinary retention
149
Indications of Hydromorphone?
Moderate-severe pain, antitussive
150
Hydromorphone 1.5 mg = _____ Morphine
10 mg
151
Hydromorphone 1 mg = _____ Morphine
7 mg (homerun:touchdown)
152
What is the brand name of Immune Globulin?
IVIG
153
What is the class of Immune Globulin?
Immune globulin replacement
154
DI with Immune Globulin?
Live virus vaccines
155
Caution with use of Immune Globulin in?
IgA deficiency, renal dysfunction, products with sucrose
156
AEs of Immune Globulin?
Infusion reactions (common) so ramp up infusion slowly (give a little, wait 30 min, repeat)
157
Indications of Immune Globulin?
Primary immune deficiencies, Kawasaki's disease, ITP
158
Dosing of Immune Globulin?
Read package insert before use or changing products
