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Practice > Abciximab-Dopamine > Flashcards

Abciximab-Dopamine Flashcards

1
Q

Class of abciximab?

A

Glycoprotein IIb/IIIa inhibitor (antiplatelet)

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2
Q

What is the brand name of Abciximab?

A

Reopro

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3
Q

What is the biggest AE of Abciximab?

A

Bleeding (also hypotension, chest pain, nausea, and back pain)

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4
Q

Can you shake the vial of monoclonal antibodies?

A

NO

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5
Q

What other two drugs are normally given with Abciximab?

A

Aspirin and heparin

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6
Q

What is the brand name of Acetylcysteine?

A

Acetadote

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7
Q

Class of Acetylcysteine?

A

Acetaminophen antidote (also used in prevention of radio-contrast induced acute renal dysfunction)

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8
Q

AE of Acetylcysteine?

A

Anaphylaxis and acute flushing (caution in asthma/bronchospasm)

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9
Q

Acetylcysteine IV vs. Oral Dosing?

A

VERY DIFFERENT

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10
Q

How long must you wait to draw samples after acetylcysteine is given to test for hepatotoxicity?

A

4 hours

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11
Q

What is the brand name for Acyclovir?

A

Zovirax

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12
Q

Class of Acyclovir?

A

Antiviral

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13
Q

Acyclovir can be nephrotoxic unless…

A

Patient is adequately hydrated

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14
Q

What is the brand name of Adenosine?

A

Adenocard

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15
Q

Adenosine is used to treat…

A

PSVT (Paroxysmal Supraventricular Tachycardia)

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16
Q

Adenosine is not effective for the treatment of…

A

A. fib, A. flutter, or V. tach

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17
Q

If a patient is not capable of doing exercise stress test, _________ is used as a pharmacologic stress agent.

A

Adenosine

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18
Q

Adenosine dosing for PSVT vs. Pharmacologic Stress in Heart Scanning?

A

PSVT- 6mg, then 12mg, repeat

Stress test- 140mcg/kg/min for 6 minutes

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19
Q

What is the brand name for Alprostadil?

A

Prostin VR

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20
Q

Must always keep this drug in stock!!!

A

Alprostadil (birth defects) and Ciprofloxacin (anthrax)

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21
Q

Used to keep ductus arteriosus open in children with congenital heart defects?

A

Alprostadil

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22
Q

What is the brand name for Alteplase, Recombinant?

A

Activase

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23
Q

Class of Alteplase?

A

Tissue plasminogen activator (clot buster)

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24
Q

Used in the management of AMI and acute ischemic stroke?

A

Alteplase, Recombinant

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25
Q

Major AE of Alteplase, Recombinant?

A

Bleeding

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26
Q

Type of stroke must be verified before dispensing?

A

Alteplase, Recombinant

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27
Q

Type of stroke Alteplase, Recombinant can be used in?

A

Acute Ischemic Stroke

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28
Q

Type of stroke Alteplase, Recombinant cannot be used in?

A

Hemorrhagic Stroke

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29
Q

What is the brand name for Amikacin?

A

Amikin

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30
Q

Dose of amikacin is about _____X the dose of gentamycin or tobramycin?

A

3

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31
Q

AE of Amikacin?

A

Nephrotoxic and Ototoxic (vertigo is irreversible)

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32
Q

Amikacin treats which bugs?

A

Gram - (even Acinetobacter)

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33
Q

What is the brand name of Amiodarone?

A

Cordarone

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34
Q

Amiodarone is CI with ________?

A

Iodine allergy (also cardiogenic shock, marked bradycardia, and AV block unless there is a pacemaker)

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35
Q

High alert medication with lots of AEs and drug interactions?

A

Amiodarone (AEs: hypotension and bradycardia)

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36
Q

Class of Amiodarone?

A

Class III antiarrhythmic

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37
Q

Indications for Amiodarone?

A

Life-threatening ventricular arrhythmias that are refractory to other treatments, ACLS (persistent VT or VF)

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38
Q

Dosing for Amiodarone?

A

Loading dose for pulseless VF or VT is 300mg IV push
Other indications: 150mg, dilute doses to 20-30mL then push
Continued dose: 1 mg/min X6hr then 0.5 mg/min

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39
Q

What is the brand name for Amphotericin B?

A

Fungizone

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40
Q

AEs of Amphotericin B?

A

Nephrotoxic (and toxic to every other organ), loss of electrolytes

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41
Q

Pretreatment for Amphotericin B?

A

NSAID, +/- APAP, +/- diphenydramine, +/- hydrocortisone, meperidine for rigors

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42
Q

What is the brand name for Anidulafungin?

A

Eraxis

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43
Q

What bugs does Anidulafungin treat?

A

Candida, Aspergillus (not Cryptococcus)

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44
Q

Class of Argatroban?

A

Thrombin inhibitor (anticoagulant)

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45
Q

AE of Argatroban?

A

Bleeding

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46
Q

Indications for Argatroban?

A

Prophylaxis and treatment of HIT

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47
Q

Warfarin + Argatroban = ?

A

Prolonged PT and INR

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48
Q

Class of Atropine?

A

Anticholinergic Agent

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49
Q

Indications for Atropine?

A

Sympatomatic Sinus Bradycardia

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50
Q

Antidote for Organophosphate poisoning?

A

Atropine

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51
Q

What is the brand name for Azithromycin?

A

Zithromax

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52
Q

DI with Azithromycin?

A

HMG-CoAs

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53
Q

Azithromycin is not monotherapy for what disease states?

A

complicated cases of PNA, GC, or syphillis

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54
Q

Azithromycin IV vs. oral dosing?

A

Similar

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55
Q

Dosing for Azithromycin by indication?

A

Varies a lot

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56
Q

Azithromycin covers which atypicals?

A

Mycoplasma, Legionella, Chlamydia, Mycobacteria Avium Complex, B. Pertussis

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57
Q

What is the brand name for Baclofen?

A

Lioresal

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58
Q

Why is Baclofen intrathecal (implantable pump)?

A

For really bad spasticity

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59
Q

Indication of Baclofen?

A

Intractable hiccups and muscle spasms

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60
Q

What is the brand name for Bumetanide?

A

Bumex

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61
Q

Dosing for Bumetanide vs. Furosemide?

A

Furosemide higher than Bumetanide

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62
Q

Class of Bumetanide?

A

Loop diuretic

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63
Q

Bumetanide AE?

A

Sulfa group, edema, electrolyte depletion (K)

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64
Q

What is the brand name of Buprenorphine?

A

Buprenex

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65
Q

Class of Buprenorphine?

A

Mixed agonist/antagonist opioid

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66
Q

What is the brand name of Butorphanol?

A

Stadol

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67
Q

Class of Butorphanol?

A

Mixed agonist/antagonist opioid

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68
Q

Mixed agonist/antagonist opioid that is often used during labor?

A

Butorphanol

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69
Q

What is the brand name for Caspofungin?

A

Cancidas

70
Q

AEs of Caspofungin?

A

Histamine reactions, headache, hypokalemia, site reactions, nephrotoxicity, LFTs

71
Q

Bugs covered by Caspofungin?

A

Candida, Aspergillus (not Cryptococcus)

72
Q

How long to infuse Caspofungin?

A

1 hour

73
Q

What is the brand name of Chlorpromazine?

A

Thorazine

74
Q

AEs of Chlorpromazine?

A

CNS depression, EPS (in 50% of those over age 60), tardive dyskinesia, drug-induced Parkinson’s, Akathisia (elderly)

75
Q

What is the brand name for Cidofovir?

A

Vistide

76
Q

Class of Cidofovir?

A

Antiviral (CMV) agent

77
Q

What is the brand name of Ciprofloxacin?

A

Cipro

78
Q

Cipro dose adjustments in _________ dysfunction?

A

Renal

79
Q

AE of Ciprofloxacin?

A

CNS effects (especially in elderly)

80
Q

DOC for Anthrax?

A

Ciprofloxacin

81
Q

Cipro is not stand alone drug unless you have….

A

Sensitivities (resistance)

82
Q

What is the brand name of Cisatracurium?

A

Nimbex

83
Q

Class of Cisatracurium?

A

Nondepolarzing neuromuscular blocking agent

84
Q

Why is Cisatracurium a high alert medication?

A

Can cause people to stop breathing if they don’t need it

85
Q

What is the brand name of Colistimethate?

A

Coly-Mycin

86
Q

Indication for Colistimethate?

A

Pseudomonas via inhaled route (not FDA approved)

87
Q

What is the brand name of Clindamycin?

A

Cleocin

88
Q

Clindamycin caution with…

A

h/o colitis, PMC, LFTs

89
Q

Infections above the diaphragm?

A

Clindamycin (PNA, intra-abdominal infections, tissue infections, and dog bites w/FQ)

90
Q

Infections below the diaphragm?

A

Metronidazole

91
Q

Indication for Clindamycin?

A

CA-MRSA, but also PNA, tissue, intra-abdominal infections, dog bites

92
Q

Bugs covered by Clindamycin?

A

Gram + and anaerobes

93
Q

What is the brand name for Dalteparin?

A

Fragmin

94
Q

Class of Dalteparin?

A

LMWH

95
Q

Dalteparin CI in…

A

Active major bleeding, HIT, epidurals, spinals (risk of epidural hematoma and paralysis)

96
Q

What is the brand name of Dantrolene?

A

Dantrium

97
Q

Class of Dantrolene?

A

Skeletal Muscle Relaxant

98
Q

Used for treatment of emergency malignant hyperthermia?

A

Dantrolene

99
Q

What is the brand name of Darbepoetin Alfa?

A

Aranesp

100
Q

Class of Darbepoetin Alfa?

A

“blood modifier” - stimulates RBCs due to the production of EPO

101
Q

Stop giving Darbepoetin Alfa when patient has high Hb or…

A

Uncontrolled Hypertension

102
Q

Darbepoetin Alfa needs adequate ______ _____ for this drug to work?

A

Iron Stores

103
Q

What is the brand name of Daptomycin?

A

Cubicin

104
Q

Daptomycin has DI with ______?

A

HMG-CoA (increased CPK)

105
Q

Daptomycin indication?

A

MRSA, strep

106
Q

Daptomycin renal adjustment if CrCl< ____mL/min?

A

30

107
Q

Daptomycin CI in what disease state?

A

PNA

108
Q

What is the brand name for Desmopressin?

A

DDAVP

109
Q

Indication for Desmopressin?

A

Diabetes insipidus, hemophilia A, von Willebrand disease (type 1), peroperative to control bleeding in hemophilia patients

110
Q

Desmopressin dosing vs. Vasopressin?

A

VERY different

111
Q

Brand name for Dexamethasone Sodium Phosphate?

A

Decadron

112
Q

Class for Dexamethasone Sodium Phosphate?

A

Long-acting glucocorticoid

113
Q

Indications for Dexamethasone Sodium Phosphate?

A

Pulmonary disease, septic shock, cerebral edema, part of some chemo regimens for N&V

114
Q

What is the brand name for Diazepam?

A

Valium

115
Q

Indication for Diazepam?

A

ETOH withdrawal (unless liver dysfunction)

116
Q

Must be given slow IV (vehicle) or causes hypotension?

A

Diazepam

117
Q

What is the brand name of Digoxin?

A

Lanoxin

118
Q

Indication for Digoxin?

A

CHF, A. flutter

119
Q

Digoxin IV forms?

A

Peds and Adult

120
Q

What is the brand name for Digoxin Immune Fab?

A

Digibind

121
Q

Used to treat digoxin overdose?

A

Digoxin Immune Fab

122
Q

What is the brand name of Diltiazem?

A

Cardiazem

123
Q

Caution with Diltiazem in…

A

Severe LV dysfunction, cardiac failure, AV-block

124
Q

Diltiazem dose Iv vs oral?

A

Similar (BOLUS 20 mg or 0.25 mg/kg followed by 10-15 mg/hr)

125
Q

What is the brand name of Diphenhydramine?

A

Benadryl

126
Q

Indications for Diphenhydramine?

A

Allergic reactions, itching, preoperative to avoid reactions, and prior to blood administration

127
Q

IV rate of Diphenhydramine?

A

25 mg/min or hypotension can occur

128
Q

What is the brand name of Dobutamine?

A

Dobutrex

129
Q

Class of Dobutamine?

A

Adrenergic agonist (beta drug)

130
Q

Indication of Dobutamine?

A

Vasopressor to stimulate contraction of the heart (similar to Dopamine, but Dopamine is beta/alpha)

131
Q

AEs of Dobutamine?

A

ectopic heartbeats, tachycardia, angina, hypotension

132
Q

What is the brand name of Dolasetron?

A

Anzemet

133
Q

Class of Dolasetron?

A

Antiemetic (5-HT3) antagonist (similar to zofran)

134
Q

Dolasetron CI with…

A

Other Drugs that Prolong QT

135
Q

What is the brand name of Dopamine?

A

Intropin

136
Q

Class of Dopamine?

A

Adrenergic agonist

137
Q

Dopamine caution with

A

tachyarrhythmias, VF

138
Q

Monitor _____ & _____ while on Dopamine?

A

BP & Kidneys

139
Q

Caution with doses above ___ mcg/kg/min Dopamine

A

15

140
Q

Infusion time of Acyclovir?

A

1 hour

141
Q

Most common dose of Acyclovir?

A

5 mg/kg q8h in adults (increased in more severe infections)

142
Q

AE of Adenosine?

A

Profound vasodilation and hypotension (short lived)

143
Q

Administration of Adenosine for PSVT?

A

Rapid IV bolus followed by saline flush for PSVT

144
Q

AE of Alprostadil?

A

Apnea (also fever, flushing, hypo or hypertension)

145
Q

Dose of Alteplase is based on…?

A

Dependent on indication

146
Q

DI with Amikacin?

A

Neuromuscular blockers (increases their effect) and other nephrotoxins

147
Q

Dose of Amikacin is based on…?

A

Peak:MIC

148
Q

Glass or polyolefin bottle for infusion and central line preferred?

A

Amiodarone

149
Q

Test dose of Amphotericin B?

A

infuse over 4-6 hours or several days

150
Q

AEs of Anidulafungin?

A

Histamine-like reactions, hypokalemia, increased LFTs, diarrhea

151
Q

Maximum infusion rate of Anidulafungin?

A

1.1 mg/min (200 mg loading dose over 3 hours, 100 mg dose over 90 min, 50 mg dose over 45 min)

152
Q

AE of Argatroban?

A

Bleeding, chest pain, hypotension (caution following LP, spinal, brain, or eye surgery, or severe hypertension

153
Q

No loading dose of warfarin?

A

Argatroban

154
Q

Used for psychotic disorders, N/V, mania, hiccups?

A

Chlorpromazine

155
Q

Infusion of Chlorpromazine?

A

No faster than 1 mg/min

156
Q

Infusion of Ciprofloxacin?

A

1 hour

157
Q

Bugs for Colistimethate?

A

Resistant gram - and/or highly allergic patients

158
Q

Monitor _______ function when on Colistimethate?

A

Renal

159
Q

Bugs for Clindamycin?

A

Gram + anaerobes

160
Q

Infusion of Clindamycin?

A

NOT A BOLUS, over 10-60 minutes

161
Q

Use of Darbepoetin Alfa?

A

Anemia from various causes

162
Q

Use of Daptomycin?

A

Skin and skin structure infections, sepsis, and right sided endocarditis

163
Q

Use of Diazepam?

A

Sedative, terminate status epilepticus, and anti-anxiety

164
Q

Active metabolites?

A

Diazepam

165
Q

Must monitor with Digoxin?

A

GI distress, CNS, and hyperkalemia

166
Q

AEs of Diltiazem?

A

Hypotension, HF, edema, fatigue, headache

167
Q

Use of DIltiazem?

A

Angina due to coronary artery spasms and hypertension

168
Q

Class of Desmopressin?

A

Vasopressin Analog and Anti-hemophilic Agent

168
Q

AEs of Diphenhydramine?

A

CNS, anticholinergics

169
Q

Antidote for Chlorpromazine OD?

A

Atropine and Neostigmine

Practice (5 decks)

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