Abciximab-Dopamine Flashcards
1
Q
Class of abciximab?
A
Glycoprotein IIb/IIIa inhibitor (antiplatelet)
2
Q
What is the brand name of Abciximab?
A
Reopro
3
Q
What is the biggest AE of Abciximab?
A
Bleeding (also hypotension, chest pain, nausea, and back pain)
4
Q
Can you shake the vial of monoclonal antibodies?
A
NO
5
Q
What other two drugs are normally given with Abciximab?
A
Aspirin and heparin
6
Q
What is the brand name of Acetylcysteine?
A
Acetadote
7
Q
Class of Acetylcysteine?
A
Acetaminophen antidote (also used in prevention of radio-contrast induced acute renal dysfunction)
8
Q
AE of Acetylcysteine?
A
Anaphylaxis and acute flushing (caution in asthma/bronchospasm)
9
Q
Acetylcysteine IV vs. Oral Dosing?
A
VERY DIFFERENT
10
Q
How long must you wait to draw samples after acetylcysteine is given to test for hepatotoxicity?
A
4 hours
11
Q
What is the brand name for Acyclovir?
A
Zovirax
12
Q
Class of Acyclovir?
A
Antiviral
13
Q
Acyclovir can be nephrotoxic unless…
A
Patient is adequately hydrated
14
Q
What is the brand name of Adenosine?
A
Adenocard
15
Q
Adenosine is used to treat…
A
PSVT (Paroxysmal Supraventricular Tachycardia)
16
Q
Adenosine is not effective for the treatment of…
A
A. fib, A. flutter, or V. tach
17
Q
If a patient is not capable of doing exercise stress test, _________ is used as a pharmacologic stress agent.
A
Adenosine
18
Q
Adenosine dosing for PSVT vs. Pharmacologic Stress in Heart Scanning?
A
PSVT- 6mg, then 12mg, repeat
Stress test- 140mcg/kg/min for 6 minutes
19
Q
What is the brand name for Alprostadil?
A
Prostin VR
20
Q
Must always keep this drug in stock!!!
A
Alprostadil (birth defects) and Ciprofloxacin (anthrax)
21
Q
Used to keep ductus arteriosus open in children with congenital heart defects?
A
Alprostadil
22
Q
What is the brand name for Alteplase, Recombinant?
A
Activase
23
Q
Class of Alteplase?
A
Tissue plasminogen activator (clot buster)
24
Q
Used in the management of AMI and acute ischemic stroke?
A
Alteplase, Recombinant
25
Major AE of Alteplase, Recombinant?
Bleeding
26
Type of stroke must be verified before dispensing?
Alteplase, Recombinant
27
Type of stroke Alteplase, Recombinant can be used in?
Acute Ischemic Stroke
28
Type of stroke Alteplase, Recombinant cannot be used in?
Hemorrhagic Stroke
29
What is the brand name for Amikacin?
Amikin
30
Dose of amikacin is about _____X the dose of gentamycin or tobramycin?
3
31
AE of Amikacin?
Nephrotoxic and Ototoxic (vertigo is irreversible)
32
Amikacin treats which bugs?
Gram - (even Acinetobacter)
33
What is the brand name of Amiodarone?
Cordarone
34
Amiodarone is CI with ________?
Iodine allergy (also cardiogenic shock, marked bradycardia, and AV block unless there is a pacemaker)
35
High alert medication with lots of AEs and drug interactions?
Amiodarone (AEs: hypotension and bradycardia)
36
Class of Amiodarone?
Class III antiarrhythmic
37
Indications for Amiodarone?
Life-threatening ventricular arrhythmias that are refractory to other treatments, ACLS (persistent VT or VF)
38
Dosing for Amiodarone?
Loading dose for pulseless VF or VT is 300mg IV push
Other indications: 150mg, dilute doses to 20-30mL then push
Continued dose: 1 mg/min X6hr then 0.5 mg/min
39
What is the brand name for Amphotericin B?
Fungizone
40
AEs of Amphotericin B?
Nephrotoxic (and toxic to every other organ), loss of electrolytes
41
Pretreatment for Amphotericin B?
NSAID, +/- APAP, +/- diphenydramine, +/- hydrocortisone, meperidine for rigors
42
What is the brand name for Anidulafungin?
Eraxis
43
What bugs does Anidulafungin treat?
Candida, Aspergillus (not Cryptococcus)
44
Class of Argatroban?
Thrombin inhibitor (anticoagulant)
45
AE of Argatroban?
Bleeding
46
Indications for Argatroban?
Prophylaxis and treatment of HIT
47
Warfarin + Argatroban = ?
Prolonged PT and INR
48
Class of Atropine?
Anticholinergic Agent
49
Indications for Atropine?
Sympatomatic Sinus Bradycardia
50
Antidote for Organophosphate poisoning?
Atropine
51
What is the brand name for Azithromycin?
Zithromax
52
DI with Azithromycin?
HMG-CoAs
53
Azithromycin is not monotherapy for what disease states?
complicated cases of PNA, GC, or syphillis
54
Azithromycin IV vs. oral dosing?
Similar
55
Dosing for Azithromycin by indication?
Varies a lot
56
Azithromycin covers which atypicals?
Mycoplasma, Legionella, Chlamydia, Mycobacteria Avium Complex, B. Pertussis
57
What is the brand name for Baclofen?
Lioresal
58
Why is Baclofen intrathecal (implantable pump)?
For really bad spasticity
59
Indication of Baclofen?
Intractable hiccups and muscle spasms
60
What is the brand name for Bumetanide?
Bumex
61
Dosing for Bumetanide vs. Furosemide?
Furosemide higher than Bumetanide
62
Class of Bumetanide?
Loop diuretic
63
Bumetanide AE?
Sulfa group, edema, electrolyte depletion (K)
64
What is the brand name of Buprenorphine?
Buprenex
65
Class of Buprenorphine?
Mixed agonist/antagonist opioid
66
What is the brand name of Butorphanol?
Stadol
67
Class of Butorphanol?
Mixed agonist/antagonist opioid
68
Mixed agonist/antagonist opioid that is often used during labor?
Butorphanol
69
What is the brand name for Caspofungin?
Cancidas
70
AEs of Caspofungin?
Histamine reactions, headache, hypokalemia, site reactions, nephrotoxicity, LFTs
71
Bugs covered by Caspofungin?
Candida, Aspergillus (not Cryptococcus)
72
How long to infuse Caspofungin?
1 hour
73
What is the brand name of Chlorpromazine?
Thorazine
74
AEs of Chlorpromazine?
CNS depression, EPS (in 50% of those over age 60), tardive dyskinesia, drug-induced Parkinson's, Akathisia (elderly)
75
What is the brand name for Cidofovir?
Vistide
76
Class of Cidofovir?
Antiviral (CMV) agent
77
What is the brand name of Ciprofloxacin?
Cipro
78
Cipro dose adjustments in _________ dysfunction?
Renal
79
AE of Ciprofloxacin?
CNS effects (especially in elderly)
80
DOC for Anthrax?
Ciprofloxacin
81
Cipro is not stand alone drug unless you have....
Sensitivities (resistance)
82
What is the brand name of Cisatracurium?
Nimbex
83
Class of Cisatracurium?
Nondepolarzing neuromuscular blocking agent
84
Why is Cisatracurium a high alert medication?
Can cause people to stop breathing if they don't need it
85
What is the brand name of Colistimethate?
Coly-Mycin
86
Indication for Colistimethate?
Pseudomonas via inhaled route (not FDA approved)
87
What is the brand name of Clindamycin?
Cleocin
88
Clindamycin caution with...
h/o colitis, PMC, LFTs
89
Infections above the diaphragm?
Clindamycin (PNA, intra-abdominal infections, tissue infections, and dog bites w/FQ)
90
Infections below the diaphragm?
Metronidazole
91
Indication for Clindamycin?
CA-MRSA, but also PNA, tissue, intra-abdominal infections, dog bites
92
Bugs covered by Clindamycin?
Gram + and anaerobes
93
What is the brand name for Dalteparin?
Fragmin
94
Class of Dalteparin?
LMWH
95
Dalteparin CI in...
Active major bleeding, HIT, epidurals, spinals (risk of epidural hematoma and paralysis)
96
What is the brand name of Dantrolene?
Dantrium
97
Class of Dantrolene?
Skeletal Muscle Relaxant
98
Used for treatment of emergency malignant hyperthermia?
Dantrolene
99
What is the brand name of Darbepoetin Alfa?
Aranesp
100
Class of Darbepoetin Alfa?
"blood modifier" - stimulates RBCs due to the production of EPO
101
Stop giving Darbepoetin Alfa when patient has high Hb or...
Uncontrolled Hypertension
102
Darbepoetin Alfa needs adequate ______ _____ for this drug to work?
Iron Stores
103
What is the brand name of Daptomycin?
Cubicin
104
Daptomycin has DI with ______?
HMG-CoA (increased CPK)
105
Daptomycin indication?
MRSA, strep
106
Daptomycin renal adjustment if CrCl< ____mL/min?
30
107
Daptomycin CI in what disease state?
PNA
108
What is the brand name for Desmopressin?
DDAVP
109
Indication for Desmopressin?
Diabetes insipidus, hemophilia A, von Willebrand disease (type 1), peroperative to control bleeding in hemophilia patients
110
Desmopressin dosing vs. Vasopressin?
VERY different
111
Brand name for Dexamethasone Sodium Phosphate?
Decadron
112
Class for Dexamethasone Sodium Phosphate?
Long-acting glucocorticoid
113
Indications for Dexamethasone Sodium Phosphate?
Pulmonary disease, septic shock, cerebral edema, part of some chemo regimens for N&V
114
What is the brand name for Diazepam?
Valium
115
Indication for Diazepam?
ETOH withdrawal (unless liver dysfunction)
116
Must be given slow IV (vehicle) or causes hypotension?
Diazepam
117
What is the brand name of Digoxin?
Lanoxin
118
Indication for Digoxin?
CHF, A. flutter
119
Digoxin IV forms?
Peds and Adult
120
What is the brand name for Digoxin Immune Fab?
Digibind
121
Used to treat digoxin overdose?
Digoxin Immune Fab
122
What is the brand name of Diltiazem?
Cardiazem
123
Caution with Diltiazem in...
Severe LV dysfunction, cardiac failure, AV-block
124
Diltiazem dose Iv vs oral?
Similar (BOLUS 20 mg or 0.25 mg/kg followed by 10-15 mg/hr)
125
What is the brand name of Diphenhydramine?
Benadryl
126
Indications for Diphenhydramine?
Allergic reactions, itching, preoperative to avoid reactions, and prior to blood administration
127
IV rate of Diphenhydramine?
25 mg/min or hypotension can occur
128
What is the brand name of Dobutamine?
Dobutrex
129
Class of Dobutamine?
Adrenergic agonist (beta drug)
130
Indication of Dobutamine?
Vasopressor to stimulate contraction of the heart (similar to Dopamine, but Dopamine is beta/alpha)
131
AEs of Dobutamine?
ectopic heartbeats, tachycardia, angina, hypotension
132
What is the brand name of Dolasetron?
Anzemet
133
Class of Dolasetron?
Antiemetic (5-HT3) antagonist (similar to zofran)
134
Dolasetron CI with...
Other Drugs that Prolong QT
135
What is the brand name of Dopamine?
Intropin
136
Class of Dopamine?
Adrenergic agonist
137
Dopamine caution with
tachyarrhythmias, VF
138
Monitor _____ & _____ while on Dopamine?
BP & Kidneys
139
Caution with doses above ___ mcg/kg/min Dopamine
15
140
Infusion time of Acyclovir?
1 hour
141
Most common dose of Acyclovir?
5 mg/kg q8h in adults (increased in more severe infections)
142
AE of Adenosine?
Profound vasodilation and hypotension (short lived)
143
Administration of Adenosine for PSVT?
Rapid IV bolus followed by saline flush for PSVT
144
AE of Alprostadil?
Apnea (also fever, flushing, hypo or hypertension)
145
Dose of Alteplase is based on...?
Dependent on indication
146
DI with Amikacin?
Neuromuscular blockers (increases their effect) and other nephrotoxins
147
Dose of Amikacin is based on...?
Peak:MIC
148
Glass or polyolefin bottle for infusion and central line preferred?
Amiodarone
149
Test dose of Amphotericin B?
infuse over 4-6 hours or several days
150
AEs of Anidulafungin?
Histamine-like reactions, hypokalemia, increased LFTs, diarrhea
151
Maximum infusion rate of Anidulafungin?
1.1 mg/min (200 mg loading dose over 3 hours, 100 mg dose over 90 min, 50 mg dose over 45 min)
152
AE of Argatroban?
Bleeding, chest pain, hypotension (caution following LP, spinal, brain, or eye surgery, or severe hypertension
153
No loading dose of warfarin?
Argatroban
154
Used for psychotic disorders, N/V, mania, hiccups?
Chlorpromazine
155
Infusion of Chlorpromazine?
No faster than 1 mg/min
156
Infusion of Ciprofloxacin?
1 hour
157
Bugs for Colistimethate?
Resistant gram - and/or highly allergic patients
158
Monitor _______ function when on Colistimethate?
Renal
159
Bugs for Clindamycin?
Gram + anaerobes
160
Infusion of Clindamycin?
NOT A BOLUS, over 10-60 minutes
161
Use of Darbepoetin Alfa?
Anemia from various causes
162
Use of Daptomycin?
Skin and skin structure infections, sepsis, and right sided endocarditis
163
Use of Diazepam?
Sedative, terminate status epilepticus, and anti-anxiety
164
Active metabolites?
Diazepam
165
Must monitor with Digoxin?
GI distress, CNS, and hyperkalemia
166
AEs of Diltiazem?
Hypotension, HF, edema, fatigue, headache
167
Use of DIltiazem?
Angina due to coronary artery spasms and hypertension
168
Class of Desmopressin?
Vasopressin Analog and Anti-hemophilic Agent
168
AEs of Diphenhydramine?
CNS, anticholinergics
169
Antidote for Chlorpromazine OD?
Atropine and Neostigmine
