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GI 2 midterm > Dobson lecture 1: Oral Cavity and Salivary gland > Flashcards

Dobson lecture 1: Oral Cavity and Salivary gland Flashcards

1
Q

Apthous Ulcer, when does it present?

A

first 2 decades

  • family prevalence
  • -Immunologic
  • IBD
  • Behcet disease
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2
Q

What is a key characteristic of fibrous proliferative lesions?

A

They are all freaking benign!

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3
Q

What are the fibrous proliferative lesions?

A

Traumatic fibroma
pyogenic granuloma
granuloma

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4
Q

What people get pyogenic granulomas?

A

children, young adults, and pregnant women (pregnancy tumor)

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5
Q

What are the infections of the oral cavity?

A

HSV1 and 2
Candida
Deep fungal infections

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6
Q

What is associated with HSV1?

A

additional clinical symptoms lymphadenopathy, fever, anorexia, and irritability
-reactivation

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7
Q

What test do we use for HSV?

A

Tzanck smear

-multinucleation

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8
Q

What is the most common fungal infection of the oral cavity?

A

Candida

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9
Q

What immunocompromised states can be happening with a candida infection?

A

HIV/AIDS
Cancer
Organ or bone marrow transplants

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10
Q

What is Torus Palatinus?

A

a growth on the ROOF OF THE MOUTH that is associated with smokers…. not cancer don’t worry

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11
Q

What is hutchinson’s teeth and what underlying agent causes that?

A

congenital syphilis case with goofy looking teeth

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12
Q

What are people with down syndrome at risk for?

A

leukemia which means a risk for periodontis

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13
Q

Which inflammatory oral lesion is familial?

A

apthous ulcer

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14
Q

which gingival lesion comes up rapidly and might make us think of malignancy?

A

pyogenic granuloma… pregnancy tumor

-remember that those fibrous proliferative lesions are all BENIGN!

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15
Q

if there’s oral HSV, which one will it be?

A

HSV1 probably

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16
Q

If you see Tzanck test, what are we looking for?

A

Herpes!!!!!

  • not specific for 1 or 2
  • multinucleation
  • the owl eye thing is CMV
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17
Q

Describe Candida

A

it’s white
YOU CAN SCRAPE IT OFF!
-they’re usually immunosuppressed

18
Q

Which deep fungal infections do we need to look out for?

A

Aspergillosis
cryptococcosis
zygomycosis (DM and mucormycosis)

19
Q

Organism associated with scarlet fever

A

group a B hemolytic strep.. strawberry tongue

20
Q

Measles?

A

three C’s

koplik spots

21
Q

Diptheria?

A

dirty white inflammatory membrane over the tonsils

22
Q

Phenytoin ingestion (Dilantin)

A

striking fibrous enlargement of the gingiva

23
Q

Hairy leukoplakia

A

CANNOT BE SCRAPED OFF

  • EBV related…
  • associated with nasopharyngeal carcinoma apparently
  • 25% precancerous
24
Q

erythroplakia

A

red, velvety, eroded lesions
-anywhere in oral cavity
-less common but more ominus
almost always severe dysplasia

25
Q

95% of head and neck cancers are ….

A

Squamous cell carcinomas

26
Q

Most common factor of precancerous lesions is….

A

Tobacco

new player is HPV

27
Q

What issue do we have with HPV…

A

p16 overexpression..

-tumor suppressor ptn

28
Q

where will you find SCC?

A

moreso on the bottom of mouth

29
Q

Is there a preceding /precancerous lesion with HPV?

A

NO

-it can just kinda pop up

30
Q

where do HPV tumors originate?

A

tonsillar cypts, base of tongue, oropharynx

-so, they’re hard to diagnose..

31
Q

Which tumors have better outcome, HPV+ or HPV-?

A

HPV+ for sure!

-even with lymph node metastasis

32
Q

Which tumor is associated with aggressive behavior and Ghorlin syndrome?

A

ODONTOGENIC cysts and tumors

-OKC’s

33
Q

What are the major players of the Salivary Gland?

A

Xerostomia
Sialadenitis
Neoplasms

34
Q

What are causes of dry mouth in patients?

A

DRUGS!!!

-Or sjogren and stuff

35
Q

Sialadenitis…. where does it come from?

A

mumps! it’s apparently unilateral

36
Q

what is the most common tumor in the salivary gland?

A

pleomorphic adenoma

-it’s benign

37
Q

How does pleomorphic adenoma present

A

well demarcated masses of varying size

  • usually from radiation
  • small mass at angle of jaw
  • recurs a lot
38
Q

What is a Warthin tumor?

A

the other benign tumor of the parotid gland only

-8x more common in smokers

39
Q

What cellular organelle is most common in oncocytic things

A

mitochondria

40
Q

Mucoepidermoid carcinoma

A

most common primary malignancy

-balanced chromosomal translocation 11-19

41
Q

Which tumor is the only one that presents with pain?

A

the adenoid cystic carcinoma

-grows along nerves so pain is common

GI 2 midterm (11 decks)

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