DNA VIRUSES PART 1: ADENOVIRUS Flashcards
Proteins involve in Human Adenovirus
Hexon, Fiber, and Core Protein
Adenovirus were first isolated from
(Adenoid tissue) adenoids surgery removed from children in 1953
Adenovirus is established as the etiological cause of what disease
Acute Respiratory Disease
Adenovirus has been isolated from every species of
mammals, birds and amphibians
Mode of Transmission of Adenovirus
Contaminated Fomites
The most common serotypes in Adenoviridae are
1 to 8, 11, 21, 35, 37, and 40
Site of latency of adenoviruses
Oropharynx
Transmission of Respiratory Adenoviruses
Aerosol and Droplet
Transmission of Enteric Adenoviruses
Fecal-Oral Route
Transmission of Conjunctivitis Adenovirus
Hand to Eye
Rarely reported adenovirus serotype but causes severe and sometimes fatal acute respiratory disease (ARD) in patients of all ages.
14
Adenovirus serotypes most commonly associated with ARD and can be fatal
3, 4 and 7
_ in feces and urine can occur for days after the symptoms have disappeared
Viral Shedding
_ was available from 1971 to 1999 for types 4 and 7 and was used only for preventing ARD in military recruits
Oral Vaccination
Incubation Period of Respiratory Disease (RD)
2-14 days
Incubation Period of GIT
3-10 days
Infectious Period
While asymptomatic
Adenovirus Serotypes that causes ARD in children
1,2,5
Adenovirus Serotypes that causes ARD in adults
3,4,7
Adenovirus Serotypes 40 and 41 are called
Enteric Adenoviruses
Prominent feature of gastroenteritis caused by enteric adenoviruses in children
Diarrhea
Enteric adenoviruses’ number of cases increases during _
warmer months
True or False:
Adenoviruses can be identified but not serotyped by EIA.
True
CPE:
Swollen cells in grapelike clusters
Respiratory Disease causes _ in children
Laryngotracheobronchitis
Most serious manifestation of respiratory disease in children
Pneumonia
Most common Adenovirus Serotypes that causes respiratory disease in children
2 and 5
Conjunctivitis with red, sore infected conjunctiva
Ocular Adenovirus
Adenovirus Serotypes for ocular adenovirus which is epidemic
8, 19, 37
Adenovirus Serotypes for ocular adenovirus which causes Pink Eye or Viral Conjunctivitis or also known as Shipyard conjunctivitis
8, 19
Adenovirus Serotypes for ocular adenovirus which causes pharyngoconjunctival fever obtained from contaminated swimming pools and also known Swimming Pool Conjunctivitis
3, 7
Pharyngoconjunctival Fever is characterized by:
Pharyngitis
Conjunctivitis
Spiking Fever
Adenovirus Serotype for Acute Hemorrhagic Cystitis
11, 21
Serotypes for Viral Gastroenteritis
40, 41
Laboratory Test:
Cell culture using various epithelial cell lines, such as
A-549, HEp-2, and He-La cells