DNA Viruses

Question 1

Parvo Virus

Answer 1

SS linear DNA
no envelope
icosahedral
parvo virus B19, adeno-associated virus

Question 2

Hepadna Virus

Answer 2

DS circular DNA
envelope
icosahedral
hepatitis B 
* mainly DS circular with regions of SS DNA

Question 3

Papilloma Virus

Answer 3

DS circular DNA
no envelope
icosahedral
HPV

Question 4

Polyoma Virus

Answer 4

DS circular DNA
no envelope
icosahedral
SV40, JC virus, BK virus

Question 5

Adeno Virus

Answer 5

DS linear DNA
no envelope
icosahedral
adenovirus - 49 serotypes in subgroups A-F

Question 6

herpes virus

Answer 6

DS linear DNA
envelope
icosahedral
herpes simplex (1,;2), varicella zoster (chickenpox), CMV, epstein-barr, human herpes 6, 7, 8

Question 7

poxvirus

Answer 7

DS linear DNA
yes envelope
BILATERAL
smallpox, vaccinia, monkey pox, or, molluscum contagiousum

Question 8

DNA viruses and cancer?

Answer 8

integrative and transforming potential– get into host cell DNA and persist, potentially causing cancer

Question 9

Which DNA viruses have circular DNA?

Answer 9

Hepadna and Papova

Question 10

How do naked viruses enter cell? enveloped?

Answer 10

magic + endocytosis; endocytosis + fusion

Question 11

Broad spectrum drugs that affect multiple viruses

Answer 11

amantidine, rimantadine, tromantadine

Question 12

immediate early proteins (alpha)

Answer 12

regulatory and evasive functions– stop host responses like interferons

Question 13

early proteins (beta)

Answer 13

regulation of cell function and replication of viral genome

Question 14

late proteins (gamma)

Answer 14

structural