DNA Transcriptions and Translations Flashcards

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1
Q

Central Dogma

A

DNA –> RNA –> Protein

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2
Q

RNA splicing

A

The process of cutting mRNAs to remove introns and retain exons, present only in eukaryotes

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3
Q

Ribonucleotide

A

Basic unit of RNA composed of a ribose sugar, nitrogenous base (A, G, C, or U), and phosphate group

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4
Q

Repressor

A

A protein that inhibits the expression of a gene

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5
Q

Telomere

A

End of chromosome made up of a repeating nucleotide sequence, present only in eukaryotes

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6
Q

Promoter

A

Region of DNA within a gene from which transcription of that gene is initiated, RNA polymerase attaches here

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7
Q

Telomerase

A

Enzyme that makes telomeres during DNA replication

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8
Q

Introns

A

Segments of immature mRNA that are spliced out in RNA splicing, present only in eukaryotes

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9
Q

Silent Mutation

A

Base change mutation that converts one codon into another sense codon encoding the same amino acid as the original codon

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10
Q

Transposons

A

A DNA sequence that can change its position within the genome, has the potential to create (or reverse) mutations

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11
Q

Messenger RNA (mRNA)

A

RNA molecules that encode the amino acid sequence of proteins during translation

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12
Q

Hormone

A

Behavior-regulating hydrophobic signaling molecule, present only in eukaryotes

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13
Q

Allosteric

A

When the three-dimensional shape of a protein changes

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14
Q

Alternative Splicing

A

The process of cutting mRNA into a different combination of exons, causing the sequence to encode different proteins, present only in eukaryotes

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15
Q

Nonsense Mutation

A

Base change that converts a codon within the coding sequence into a stop codon

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16
Q

Missense Mutation

A

Base change that converts one codon into another sense codon

17
Q

Poly(A) Tail

A

Long tail of As on 3′ end of mRNAs, present only in eukaryotes

18
Q

Non-Conservative Mutation

A

A mutation which changes an amino acid to another amino acid that does not have similar biochemical properties

19
Q

Ribosome

A

Protein factory, made up of RNA and protein that mediate translation of mRNAs into protein

20
Q

Translation

A

The process of synthesizing a protein from a segment of RNA

21
Q

Frameshift Mutation

A

Addition or deletion of either one or two base pairs in a way that alters the coding sequence

22
Q

Insertion

A

Mutation in which extra base pairs are inserted into the open reading frame in a new place in DNA

23
Q

5′ - Cap

A

G-triphosphate cap on the 5′ end of mRNAs, present only in eukaryotes

24
Q

Exons

A

Segments of mRNA that are retained after splicing, present only in eukaryotes

25
Q

Transfer RNA (tRNA)

A

RNA molecules that recruit amino acids to the corresponding mRNA sequence within the ribosome during translation

26
Q

Hormone Receptor

A

Protein that binds hormone; can be located in the cytoplasm, cell membrane, or nuclear membrane; present only in eukaryotes

27
Q

Operon

A

A group of genes with related functions under the control of a single promoter, present in prokaryotes

28
Q

Reverse Transcriptase

A

RNA-directed DNA polymerase; The process of generating complementary DNA from an RNA template, present only in viruses

29
Q

Polyadenylation Site

A

The position on mRNA sequences where a poly(A)tail is attached, present only in eukaryotes

30
Q

Deletion

A

Mutation is which base pairs from within the open reading frame are deleted

31
Q

Retrovirus

A

Single-stranded RNA virus that carries reverse transcriptase

32
Q

Proof of evolution

A

we are sharing the same genetic code

33
Q

Start / stop codon

A

where the translation starts and ends

34
Q

Transcription process for Eukaryotic cells

A

Promoter –> transcriptase –> immature RNA –> mature RNA –>

35
Q

Telomere

A

End of chromosome made up of a repeating nucleotide sequence, present only in eukaryotes; to prevent losing of genetic materials in the process of DNA replication (primer does not start at the very beginning of the chromosomo): TTAGGG

36
Q

Immature RNA

A

Initial transcription Messager RNA

37
Q

mature RNA

A

mRNA after RNA splicing