DNA Transcriptions and Translations Flashcards

1
Q

Central Dogma

A

DNA –> RNA –> Protein

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2
Q

RNA splicing

A

The process of cutting mRNAs to remove introns and retain exons, present only in eukaryotes

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3
Q

Ribonucleotide

A

Basic unit of RNA composed of a ribose sugar, nitrogenous base (A, G, C, or U), and phosphate group

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4
Q

Repressor

A

A protein that inhibits the expression of a gene

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5
Q

Telomere

A

End of chromosome made up of a repeating nucleotide sequence, present only in eukaryotes

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6
Q

Promoter

A

Region of DNA within a gene from which transcription of that gene is initiated, RNA polymerase attaches here

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7
Q

Telomerase

A

Enzyme that makes telomeres during DNA replication

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8
Q

Introns

A

Segments of immature mRNA that are spliced out in RNA splicing, present only in eukaryotes

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9
Q

Silent Mutation

A

Base change mutation that converts one codon into another sense codon encoding the same amino acid as the original codon

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10
Q

Transposons

A

A DNA sequence that can change its position within the genome, has the potential to create (or reverse) mutations

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11
Q

Messenger RNA (mRNA)

A

RNA molecules that encode the amino acid sequence of proteins during translation

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12
Q

Hormone

A

Behavior-regulating hydrophobic signaling molecule, present only in eukaryotes

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13
Q

Allosteric

A

When the three-dimensional shape of a protein changes

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14
Q

Alternative Splicing

A

The process of cutting mRNA into a different combination of exons, causing the sequence to encode different proteins, present only in eukaryotes

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15
Q

Nonsense Mutation

A

Base change that converts a codon within the coding sequence into a stop codon

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16
Q

Missense Mutation

A

Base change that converts one codon into another sense codon

17
Q

Poly(A) Tail

A

Long tail of As on 3′ end of mRNAs, present only in eukaryotes

18
Q

Non-Conservative Mutation

A

A mutation which changes an amino acid to another amino acid that does not have similar biochemical properties

19
Q

Ribosome

A

Protein factory, made up of RNA and protein that mediate translation of mRNAs into protein

20
Q

Translation

A

The process of synthesizing a protein from a segment of RNA

21
Q

Frameshift Mutation

A

Addition or deletion of either one or two base pairs in a way that alters the coding sequence

22
Q

Insertion

A

Mutation in which extra base pairs are inserted into the open reading frame in a new place in DNA

23
Q

5′ - Cap

A

G-triphosphate cap on the 5′ end of mRNAs, present only in eukaryotes

24
Q

Exons

A

Segments of mRNA that are retained after splicing, present only in eukaryotes

25
Transfer RNA (tRNA)
RNA molecules that recruit amino acids to the corresponding mRNA sequence within the ribosome during translation
26
Hormone Receptor
Protein that binds hormone; can be located in the cytoplasm, cell membrane, or nuclear membrane; present only in eukaryotes
27
Operon
A group of genes with related functions under the control of a single promoter, present in prokaryotes
28
Reverse Transcriptase
RNA-directed DNA polymerase; The process of generating complementary DNA from an RNA template, present only in viruses
29
Polyadenylation Site
The position on mRNA sequences where a poly(A)tail is attached, present only in eukaryotes
30
Deletion
Mutation is which base pairs from within the open reading frame are deleted
31
Retrovirus
Single-stranded RNA virus that carries reverse transcriptase
32
Proof of evolution
we are sharing the same genetic code
33
Start / stop codon
where the translation starts and ends
34
Transcription process for Eukaryotic cells
Promoter --> transcriptase --> immature RNA --> mature RNA -->
35
Telomere
End of chromosome made up of a repeating nucleotide sequence, present only in eukaryotes; to prevent losing of genetic materials in the process of DNA replication (primer does not start at the very beginning of the chromosomo): TTAGGG
36
Immature RNA
Initial transcription Messager RNA
37
mature RNA
mRNA after RNA splicing