Dna Rna Genetics Flashcards
DNA has what bases
Adinine, Thymine, Guanine, Cytocine
Ribonucleic Acid
RNA ribose has an extra oh group
RNA
Has base of uracil instead of thymine
Single strand helix
How was DNA discovered?
In 1953 Maurice Wilkins and Rosalind Franklin took X ray diffraction images of DNA
Genotype
A sequence of nucleotide bases in DNA
Phenotype
Organisms specific traits.
What is transcription?
The transfer of genetic info from DNA to RNA.
Producing mRNA. Happens in the nucleus.
What is translation?
Converting information of RNA into proteins. Uses ribosomes to read mRNA to bring in tRNA and build polypeptides
What is genetic code?
nucleotide sequence built into amino acid sequence.
What are codons?
Triplets of bases. Sets of three letters that specify a specific amino acid.
What is a polypeptide?
Chain of amino acids, a protein
How fast does DNA replicate?
50 nucleotides/ sec
Replicates from 5’ to 3’ ends
Can repair damaged DNA
Codons and Amino acids
Codes of three letters that represent different amino acids. Can build 20 types of amino acids.
Steps to protein
1 translation
2 RNA processing
3 amino acid attachment
4 initiation of translation
5 elongation ( using anti codon and codon)
6 termination ( using stop codon)
Mutations
Any change in normal sequence
Mutation types
- base substitution
- deletions
- insertions
Mutations may result from?
-Errors in DNA replication or in recombination ( crossing over)
-mutagens can act as carcinogens, physical or chemical agents such as x- rays, uv light, chemicals
Mutations may be harmful or helpful
- may lead to genetic disease or cancer
-may lead to diversity of genes
Transcription and translation
Translation from nucleic acid language to amino acid language
Gene
Section of DNA that has a recipe for proteins
Protein synthesis
Occurs through transcription and translation.
DNA and RNA
Shared by all life
Intron
a segment of a DNA or RNA molecule which does not code for proteins and interrupts the sequence of genes.
tRNA
Transfer RNA molecule
Connects to codon to build amino acid
mRNA
Connects to tRNA codon
Stop codon
Tells tRNA where to stop