DNA repair and genetics of cancer Flashcards
1
Q
What does spontaneous deamination cause?
A
conversion of cytosine to uracil
2
Q
How many hallmarks of cancer are there?
A
8
3
Q
What is the major impact of theRB mutation in cancer?
A
Proliferative signalling
4
Q
BRCA1 is involved in which DNA repair pathway?
A
Homologous recombination
5
Q
How many key proteins are in the RAS family?
A
3
6
Q
what is the major function of K-RAS?
A
intracellular cell signalling molecule
7
Q
Which cancer has Chernobyl been linked with?
A
Thyroid cancer
