dna Flashcards
DNA polymerase does what
Proofread each new nucleotide
Find errors in base pairing
what does DNA helicases do
unzips double helix
Topoisomerases
– prevent tangling and knotting
what is Transcription
Synthesizes messenger RNA (mRNA)
– complementary to template DNA strand
what is Translation
Synthesizes polypeptide chain
– specified by mRNA
(tRNA) is
“Decoding” molecule in translation has anticodons
what to do Ribosomes in transtation
– Couple tRNAs to mRNA codons
– Catalyze peptide bonds between amino acids
introns
noncoding regions (interrupt exons) – removed from original pre-mRNA
exons
– coding regions in eukaryotic genes
– spliced to produce continuouspolypeptide
Frameshift Mutations
Insertion or deletion of one or two base
pairs in a gene
Transposons
Movable DNA sequences
– “jump” into the middle of a gene
cellular reproduction by prokaryotes?
- Binary fission
Nucleosome are (3)
histone (protein) bead wrapped in DNA
– organized into coiled loops
– held together by nonhistone scaffolding
proteins
sister chromatids
containing identical DNA sequences
Centromere is
constricted region
– joins sister chromatids