DNA Flashcards
What is the backbone of DNA made up of?
Deoxyribose and phosphate
What part of a DNS molecule contains nitrogen?
Bases
T A G C
What are the bonds that hold bases together?
Hydrogen bonds
How does a changed in DNA sequence result in a non-functional enzyme
Change in base sequence of AA
Change in bonds e.g. Tertiary structure
Enzyme different shape
substate can no longer bind to active site
What is the purpose of deoxyribose sugar?
Give structure and stability
What is the purpose of the phosphate group?
Protect data from chemical and physical forces from outside
What are the bond between deoxyribose and phosphate
Phosphodiester bonds
What are the purpose of hydrogen bonds in DNA
Week hydrogen bonds separate easily during DNA replication
What is pyridimine?
One ring
C & T
What is purine
Double Ring
G & A
What are the properties of faces that make them join together
They are complementary and specific
What single units is DNA made up of?
Mononucleotides
Make up polynucleotides
How can a sequence of DNA be changed
Mutation:-
Substitution – exchanging one base for another
Insertion – adding extra base has e.g. codon
Deletion – sections of DNA are lost
Frameshift – and thousands of solutions that disrupt codons
What happens when DNA mutates?
Causes no change Alter the single amino acid Codes for different amino acid Animo acid cannot be produced Changes to stop codon
Protein therefore may not be produced
How many amino acids can DNA code for?
20