DNA Flashcards
The Code of Life
- inherited traits give us sae features to parents
- genes are carried on chromosomes in DNA form
- inherrited and respobible for pheotyphic chartestertics
Friedrich Miescher
- 1869
- he isolated a compound found in the nucleus of cell
- named compound nuclein
- many scientists did studys after to see if it was heridetery material
nucleiod and heridty
nuclein was discovered in the 1920s, but it took decades still to determine it was responsible for heredity
Joachim Hammerling
- In the 1930
- single-celled algae would regrow if the nucleus was still present
- detrmined nucleus must contain the genetic material
Alfred Hershey and Martha Chase
- proved hammerlings hyponthsis in 1952
how did hershey and chase prove hammerlings hypthosis
- showing that viruses only need to inject their DNA into a cell to take over their organelle to produce more virus
- proved that DNA was the hereditary material
Chemical Composition of DNA
A pentose sugar (5 carbon cyclical sugar)
A phosphate group with a negative charge
A nitrogenous base
components together are called a nucleotide
Phoebus Levene
- 1920s
- discovered DNA had 3 main components
4 possible nitrogenous bases
- make up the nucleotides of DNA
Adenine (A)
Guanine (G)
Thymine (T)
Cytosine (C)
relationship between the nitrogenous bases
The amount of Adenine =
The amount of Thymine
The amount of Guanine =
The amount of Cytosine
crucial clue that helped determine the structure of DNA
Rosalind Franklin
- scientists did not know struture to DNA
- work with Maurice Wilkins
- In 1951
- studied DNA using X-ray crystallography
- discovered that the DNA molecules must have a helix, or corkscrew, shape
James Watson and Francis Crick
- In 1953
- met with Wilkins and stole franklins idea
- everyone knew the shap eof DNA< double helix
main events of DNA
- DNA is made of a pentose sugar, a phosphate group and nitrogenous bases (Levene, 1920s)
- The proportion of A to T and C to G is equal (Chargaff, 1940)
- DNA has the shape of a helix (Franklin and Wilkins, 1951)
Erwin Chargaff
- In 1940
- discovered a key relationship about the nitrogenous bases
events in order
- 1869, Friedrich Miescher
- 1920s, Phoebus Levene
- 1930s, Joachim Hammerling
- 1940, Erwin Chargaff
- 1951, Rosalind Franklin and Wilkins
- 1952, Alfred Hershey and Martha Chase
- 1953, James Watson and Francis Crick