DMD - L3 Flashcards
1
Q
Topics?
A
DMD statistics clinical presentations diagnosis disease progression complications BMD statistics disease progression
2
Q
DMD statistics?
A
onset
3
Q
DMD clinical presentations? (7)
A
delayed motor milestones (walking >18 months)
gait difficulties (proximal, Gower’s manoeuvre)
enlarged, rubbery muscles
weak neck flexors
lumbar lordosis
fatigability
speech delay, learning problems
4
Q
DMD diagnosis?
A
serum creatine kinase (normal
5
Q
DMD disease progression?
A
3-6 years
8 years
10-13 years
teen-early 20s
6
Q
DMD complications? (6) Explain each one
A
respiratory deficit sleep-disordered breathing cardiac involvement orthopaedic involvement CNS involvement cognitive issues
7
Q
BMD statistics?
A
onset >5 years
incidence 1/35,000 male births
clinical onset variable
wheelchair dependency >16yrs
8
Q
BMD disease progression?
A
-
