DM ppt Flashcards

1
Q

DM risk factors

A
genetics
obesity
race/ethnicity
age
HTN
high HDL
gestational diabetes, baby >9 lbs
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2
Q

DM 1

A

FKA brittle diabetes, juvenile diabetes
beta cells in panrease are destroyed
decreased insulin production and unchecked glucose production
5% of DM

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3
Q

DM 2

A

95% of DM
most common in obese >30 y/o
insulin resistance
impaired insulin secretion

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4
Q

gestational diabetes

A

hyperglycemia develops with pregnancy 2/2 secretion of placental hormones
r/o HTN during pregnancy
highest risk: obesity, Hx of gestational diabetes, glycosuria, genetics

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5
Q

latent autoimmune diabetes of adults (LADA)

A

progression of autoimmune beta cell destruction is slower than in DM1/DM2
not insulin dependent initially

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6
Q

3 Ps

A

polyuria
polydipsia
polyphagia

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7
Q

DM diagnostic findings

A

casual glucose reading > 200mg/dL
flasting glucose >126 mg/dL
greater than 200mg/dL in oral glucose tolerance
A1C > 6.5%

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8
Q

DM medical mgmt

A
A1C < 7%
nutritional therapy
exercise
monitoring
medication
educatoin
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9
Q

nutritional therapy

A

control of total caloric intake to maintain or attain reasonable body weight
control blood glucose levels
meal planning
maintain pleasure of eating

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10
Q

meal planning

A

carbs: 50-60%
fat: 30%
cholesterol: <300mg
non animal sources of protein

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11
Q

rapid acting insulin

A

shorter duration

eat within 5-15 min

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12
Q

short acting insulin

A

clear solution
given 15 min prior to meal
can be given IV

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13
Q

intermediate acting insulin

A

NPH or Lente
white and cloudy soltuion
should eat food around onset/peak

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14
Q

long acting “peakless” insulin

A

absorbed over 24 hrs

given once daily at the same time

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15
Q

conventional insulin therapy

A
pt should not vary meal patterns
1-4 injections qd
appropriate for:
terminally ill
frail older adult with self-care limitations
pts unwilling to do self mgmt
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16
Q

complications of insulin therapy at injection site

A

redness, swelling, tenderness, induration, 2-4 cm wheal at site
may appear 1-2 hr after injection
another type of insulin may be needed

17
Q

complications of insulin therapy (systemic)

A

rare
immediate skin reaction that spreads in hives
associated with edema, anaphylaxis
give desensitization kit

18
Q

complications of insulin therapy: insulin lipodystrophy

A

localized reaction at injection site

lipoatrophy: dimpling, loss of subcutaneous fat (mostly resolved with use of human insulin)
lipohypertrophy: development of fibrofatty masses at injection sites caused by repeated use of site; absorption may be delayed

19
Q

complications of insulin therapy: resistance

A

immune antibodies develop and bind the insulin
all insulins cause antibody production
treated by administering a more concentrated insulin

20
Q

complications of insulin therapy: morning hyperglycemia

A

insulin waning
dawn phenomenon
Somogyi effect

21
Q

insulin waning

A

progressive rise in glucose from bedtime to moring

increase evening dose or administer before evening meal

22
Q

dawn phenomenon

A

normal until 3 am. then level begins to rise

change time of evening insulin from dinner time to bedtime

23
Q

Somogyi effect

A

normal at bedtime, decrease 2-3 am caused by production of counter regulatory hormones

decrease evening dose or increase evening snack

24
Q

insulin pens

A

prefilled cartridges loaded into pen-like holder
attach disposable needle
convenient for eating out, traveling

25
Q

jet injectors

A

deliver insulin under skin through a fine stream
expensive, require training
insulin absorbed faster

26
Q

insulin pumps

A

small and worn externally
needle/cath in subcutaneous tissue gets changed every 3 days
infused at basal rate; calculates carbs at meal
good for people with hectic lifestyles

27
Q

insulin pump issues

A

tubing may get dislodged
battery is depleted
supply of insulin runs out

28
Q

oral antidiabetic agents

A

used for DM2 patients

major side effect: hypoglycemia