Diuretics and RAAS Antagonists II Flashcards
1
Q
ACEI target and MOA
A
- decreases AII-induced release of aldosterone and moderates myocardial hypertrophy and remodeling
- decreases bradykinin inactivation
2
Q
ACEI role in tx of HF
A
prevent remodeling and reduce symp act
3
Q
ACEI adverse effects
A
- inc plasma K+
- hypotension
- chronic dry cough
- don’t take while pregnant
4
Q
Angiotension receptor blockers target and MOA
A
selective inhibition of AII receptor AT1 – prevent remodling and reduce sympathetic act
5
Q
Angiotensin receptor blockers role in the tx of HF
A
prevent remodeling and reduce symp act
6
Q
ARB adverse effects
A
-inc plasma K+
-hypotension
NO COUGH
-Don’t take while pregnant
