Diuretics and Other Renal Drugs

Question 1

Group of drugs that reduces carbonic acid yielding fewer H+ exchanged for Na+ from the lumen, causes less Na+ reabsorption and more is available to combine with HO3-

Answer 1

Carbonic Anhydrase Inhibitors

Question 2

Group of diuretics that causes the least distortion of extracellular fluid ion levels, active at the early part of distal tubule blocks Na-Cl cotransport at the site of action.

Answer 2

Thiazide Diuretics

Question 3

also known as ceiling diuretics

Answer 3

loop diuretics

Question 4

Examples of Potassium-sparing diuretics

Answer 4

Triamterene and Amiloride, Spironolactone

Question 5

Potassium-sparing diuretics inhibits Na+ reabsorption in the distal cinvuluted tubule and collecting ducts

Answer 5

Triamterene and Amiloride

Question 6

A competitive antagonist of the mineralocorticoid aldosterone, redices aldosterong-mediated Na+-K+ exchange at the late distal convoluted tubule, increasing Na+ loss while decreasing K+ loss

Answer 6

Spironolactone