Disorders of the Pituitary

Question 1

Are disorders of the Pituitary usually anterior or posterior?

Answer 1

Anterior pituitary

Question 2

What are most pituitary disease caused by?

Answer 2

Adenomas

Question 3

Hyperactivity of the AP can be affecting trophic and non trophic hormones. They can be functional or non functional. Explain what functional, and non functional would cause to happen?

Answer 3

Functional = increased secretion
Nonfunctional = not secreting

Question 4

What would be an example that would be caused by hypersecretion of the AP?

Answer 4

The glands that it is targetting to be stimulated, excessively

Question 5

Hyperactivity of the PP, what is the main disease we look at?

Answer 5

Syndrome of Inappropriate Anti Diuretic Hormone (SIADH)

Question 6

What does the ADH cause to happen?

Answer 6

Water to be retained, sodium will follow

Question 7

in SIDAH, is there hyper or hyposecretion of ADH?

Answer 7

HYPER!

Question 8

What is the etiology of SIADH?

Explain how this etiology works?

Answer 8

Ectopic tumors: secreting chemicals that act like ADH, so they bind to ADH receptors on the collecting tubules in the kidney

Question 9

What does SIADH cause to happen? (3)

Answer 9

1. ^^ Water Rention, Na+ will then follow
2. Dilutional Hyponatremia (fluid in excess retained, Na+ in normal concentration
3. RAAS not happening (d/t high BP of the fluid being retained, therefore Na+ not being reabsorbed.)

Question 10

What is the treatment for SIADH?

1. Mild
2. The other 2 Tx’s

Answer 10

1. restrict fluids
2. Diuretics
3. ADH antagonsits (block receptors)