Disorders of Fluid, Electrolyte, & Acid-Base Imbalaces Flashcards

(53 cards)

1
Q

Intracellular fluid

A

fluid inside the cells

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2
Q

Extracellular fluid

A

fluid outside of the cells

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3
Q

Interstitial fluid

A

fluid between the cells

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4
Q

Intravascular fluid

A

fluid inside the blood vessels

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5
Q

Transcellular fluid

A

third space Ex: CSF and eye

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6
Q

Thirst mechanism

A

triggered by decreased blood volume and increased osmolarity

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7
Q

Antidiuretic hormone (ADH)

A
  • Promotes reabsorption of water in the kidneys

- Produced by the hypothalamus

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8
Q

Aldosterone

A

Increases re-absorption of sodium and water in the kidneys

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9
Q

Atrial natriuretic peptide (ANP)

A

stimulates renal vasodilation and suppresses aldosterone, increasing urinary output
-comes from the atrium in response to too much fluid in the heart

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10
Q

Isotonic

A

equal solute concentrations; no fluid shifts

  • normal saline
  • lactated ringers
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11
Q

Hypotonic

A

lower solute concentrations; causes fluids to shift out of vasculature and into cell
-0.45% saline

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12
Q

Hypertonic

A

Higher solute concentrations; causes fluids to shift into ECF & vasculature and out of the cell
-5% dextrose in NS; 3% saline

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13
Q

Major illnesses caused by fluid imbalance

A

Heart Failure
Renal disease
Trauma (blood loss)

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14
Q

Therapeutic measures for illness caused by fluid imbalance

A

IV fluids
Medication (diuretics)
NPO status
NG suctioning

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15
Q

Causes of hypovolemia

A
Inadequate fluid intake
excessive fluid losses/ dehydration
Fluid shifts
Fever
Decreased blood volume and plasma
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16
Q

Manifestations of hypovolemia

A
  • Tachy then brady
  • increased cap refill
  • outcome is shock
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17
Q

Causes of hypervolemia

A
  • Edema
  • Fluid volume excess
  • Water intoxication
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18
Q

Sodium (Na)

A
  • normal level 135-145 mEq/L
  • regulates ECF volume and osmolarity
  • water follows salt
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19
Q

Causes of hypernatremia

A
  • dehydration
  • overuse of IV solutions
  • impaired renal function
  • Na administration
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20
Q

Causes of hyponatremia

A
  • excessive water
  • loss of Na from vomiting, diarrhea, GI suctioning, sweating
  • use of diuretics, renal disease
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21
Q

Manifestations of hypernatremia

A
  • increased temperature
  • increased thirst
  • irritability, agitation
  • decreased urine output
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22
Q

Manifestations of hyponatremia

A
  • anorexia, GI upset
  • poor skin turgor
  • diminished deep tendon reflexes, muscle weakness
23
Q

Chloride (Cl)

A
  • normal levels 96-106 mEq/L
  • most abundant extracellular anion
  • works with Na to maintain osmotic pressure in serum
  • Increase and decrease due to similar factors that affect Na
24
Q

Potassium (K)

A
  • normal level 3.5-5 mEq/L
  • maintains intracellular osmolarity
  • controls cell resting potential
  • small changes = cardiac muscle effects
  • works opposite of Na
25
Causes of hyperkalemia
- Deficient excretion - Excessive K intake - Increased K release from cells
26
Causes of hypokalemia
- Excessive K loss - deficient K intake - increased shift into the cell
27
Manifestations of hyperkalemia
- respiratory depression - abdominal cramping - nausea and diarrhea
28
Manifestations of hypokalemia
- leg cramps - hypotension - decreased bowel sounds - abdominal distention - constipation, ileus
29
What will happen to blood K+ levels when the client has hyperaldosteronism?
Hypokalemia
30
What will happen to blood K+ levels when the client has alkalosis?
Hyperkalemia
31
What will happen to blood K+ levels when the client has an injection of epi?
hypokalemia
32
What will happen to blood K+ levels when the client has convulsions?
Hypokalemia
33
What will happen to blood K+ levels when the client has loop diuretics?
Hypokalemia
34
Calcium (Ca)
- normal levels 8.5-10.8 mEq/L - closely regulated by kidneys & parathyroid hormone - inverse relationship with phosphorus - synergistic relationship with magnesium
35
Calcium is regulated by..
- Vitamin K - parathyroid hormone - Calcitonin- comes form the thyroid; thyroid problems equal calcium problems
36
Causes of hypercalcemia
- increased intake or release | - deficit excretion
37
Causes of hypocalcemia
- excessive losses | - deficient intake
38
Manifestations of hypercalcemia
- decreased memory - headache - muscle weakness, decreased deep tendon reflexes
39
Manifestations of hypocalcemia
- increased bleeding tendencies - increased deep tendon reflexes, muscle spams, tetany - seizures - laryngeal spasms* - positive Trousseau's sign - positive Chvostek's sign
40
Phosphorus
- normal levels 2.5-4.5 mg/dL - bone and ATP formation - glucose, fat, protein metabolism - inverse relationship with calcium - acid base buffer
41
Magnesium (Mg)
- normal levels 1.3-2.1 mg/dL - cofactor in enzyme reactions - ATP generation - DNA replication - Blocks K+ exit from cardiac cells - Smooth muscle relaxant
42
Causes of hypermagnesemia
renal failure | excessive laxative and antacid use
43
Causes of hypomagnesemia
- inadequate intake - chronic alcoholism - malnutrition - pregnancy - diarrhea - stress
44
Manifestations of hypermagnesemia
``` Similar to hypercalcemia; think RENAL: Reflexes decreased EKG changes N/V Appearance flushed Lethargy/drowsiness/coma ```
45
Manifestations of hypomagnesemia
Similar to hypocalcemia
46
Acid (H+)
controls respiratory rate
47
Volatile acid
H2CO3
48
Nonvolatile acid
- Lactic acid: energy metabolism - Hydrochloric acid: digestion - ketoacids: "food" for brain
49
pH
- normal value 7.35-7.45 - regulated by chemical buffer systems and lungs (eliminate CO2) - kidneys eliminate H+, reabsorb/generate HCO3-
50
Metabolic acidosis
- increased H+ = low pH - decreased bicarbonate - heavier breathing causes decreased PCO2
51
Metabolic alkalosis
- decreased H+ = high pH - increased bicarbonate - lighter breathing causes increased PCO2
52
Respiratory acidosis
- increased PCO2 - increased carbonic acid - increased H+ = low pH - increased bicarbonate
53
Respiratory alkalosis
- decreased PCO2 - decreased carbonic acid - decreased H+ = high pH - decreased bicarbonate