Diseases of Salivary Glands- Non Neoplastic (Panopto) Flashcards
The parotid gland is mostly composed of:
Serous acinar cells
What type of cells can be seen in this image? What gland is this?
Serous acinar cells; parotid gland
What may be particularly seen in histological images of the parotid gland?
fat cells
Serous acinar cells of the parotid gland are very _____ because they contain _____
granular; zymogens
The _____ gland contains 100% serous acinar cells
parotid
The submandibular gland is a _____ gland
seromucous
This stain is really highlighting the mucous acinar cells in red, what gland is seen here?
submandibular
The sublingual gland is comprised of ____ & _____ acinar cells but is mostly _____
mucous & serous; mucous
The histological slide on the right shows many mucous acinar cells. What gland is seen? What cells are stained red? What cells are stained brown?
Sublingual
red= mucous acinar cells
brown= serous acinar cells
Two locations in which we see a lot of minor salivary glands:
palate & retromolar pad area
-minor salivary gland
-circumvalate papillae
-serous acinar
Glands of von Ebner
-minor salivary gland
-foliate papillae
-mucous acinar
Glands of Weber
-minor salivary gland
-anterior ventral
-mucuos acinar
Glands of Blandin and Nunn
Disruption in the ductal system that causes mucous to get trapped inside the connective tissue forming a little balloon or bubble:
mucocele (mucous extravasation reaction)
The patient has a history of trauma (biting their lip) resulting in the bluish abnormality, what is the likely diagnosis?
mucocele
This is a mucocele occurring on the bottom side of the tongue, what glands are involved?
Glands of blandin and Nunn
What can be seen in this histological slide? Pt experienced trauma prior to coming in.
Mucocele (Granulation tissue trying to wall off the mucocele)
Common place to find superficial mucoceles:
palate
What can be seen in this image?
superficial mucoceles
Special type of mucocele associated with the sublingual gland:
ranula
When mucin discescts through the mylohyoid muscle presenting as a neck mass:
plunging ranula
Mucin that gets trapped inside the salivary ductal system, resulting in the mucin to calcify:
Sialolith (salivary stone)
The ductal system that is most commonly affected by sialoliths:
Wharton’s gland
Patient comes in complaining of episodic swelling particularly around meal times, and experiences pain due to this- this is a sign of:
A sialolith
(no way for saliva to flow through ductal system because its blocked by a stone resulting in swelling)
Patient presents with this and you note it is very hard upon palpation. What is the diagnosis? What gland is this associated with?
Sialolith- Wharton’s duct
What type of radiograph would you order if you suspect a sialolith in Wharton’s duct?
Occlusal radiograph
Necrotizing sialometaplasia can be described as:
A completely reactive condition
Your patient comes in and states “a piece of the roof of their mouth plopped out” with only this info, what would be your diagnosis?
necrotizing sialometaplasia
Patient comes in with B/L areas of ulceration on the roof their mouth, what is the diagnosis?
necrotizing sialometaplasia
Histologically appears as if the epithelium is pinching off at the surface going into the connective tissue, but is NOT cancerous (pseudoepitheliomatous hyperplasia)
necrotizing sialometaplasia
- Pseudoepitheliomatous hyperplasia
- Sialometaplasia
- Coagulative necrosis of the glands
Histologically these may all represent:
necrotizing sialometaplasia
This histological slide shows squamous metaplasia of the salivary gland tissue, what is this characteristic of?
necrotizing sialometaplasia
Your patient comes in with extremely dry mouth & dry eyes, and remembers they were diagnosed with an autoimmune disorder but doesn’t recall which one. What condition do they have and what does this effect?
Sjogren syndrome; salivary gland tissue
Sjogren syndrome where there is NOT another diagnosis of an additional autoimmune disease:
Primary
Sjogren’s syndrome + additional diagnosis of another autoimmune disease:
Secondary
Patient presents with B/L enlargement of the parotid gland. You perform a biopsy and this biopsy comes back as BLEL (benign lympho-epithelial lesion which is also known as mikuliczs disease) what is your diagnosis?
Sjogren syndrome
How can you diagnose Sjorgrens syndrome through laboratory values?
List values specific sjogren syndrome, list values nonspecific to sjogrens syndrome:
Specific: Anti-SS-A & Anti-SS-B
Nonspecific: RF & ANA
This patient has asymmetrical enlargement of the parotid glands, what is a likely diagnosis?
Sjogren sundrome
Anti-SS-a may also be known as:
Anti-ss-B may also be known as:
A these are labarotry values for:
Anti-Ro
Anti-La
Sjögren’s syndrome
Whenever you have a systemic disease that affects the major glands this also:
Give an example of when this occurs
Mimics in the minor glands; Sjögren’s syndrome
When performing a lower lip biopsy to harvest some cells, you find lymphoid clusters. You also see that the acinar cells have been completely destroyed leaving remnants of the ducts. There is a high number of the clusters and destroyed acinar cells, what is your diagnosis?
Sjogrens sydrome
Patient presents with dry mouth & dry eyes, mouth sticks to tongue depressor, rampant caries, diagnosis?
Sjögren’s syndrome
