Diseases of Salivary Glands- Non Neoplastic (Panopto)

Question 1

The parotid gland is mostly composed of:

Answer 1

Serous acinar cells

Question 2

What type of cells can be seen in this image? What gland is this?

Answer 2

Serous acinar cells; parotid gland

Question 2

What may be particularly seen in histological images of the parotid gland?

Answer 2

fat cells

Question 3

Serous acinar cells of the parotid gland are very _____ because they contain _____

Answer 3

granular; zymogens

Question 4

The _____ gland contains 100% serous acinar cells

Answer 4

parotid

Question 5

The submandibular gland is a _____ gland

Answer 5

seromucous

Question 6

This stain is really highlighting the mucous acinar cells in red, what gland is seen here?

Answer 6

submandibular

Question 7

The sublingual gland is comprised of ____ & _____ acinar cells but is mostly _____

Answer 7

mucous & serous; mucous

Question 8

The histological slide on the right shows many mucous acinar cells. What gland is seen? What cells are stained red? What cells are stained brown?

Answer 8

Sublingual
red= mucous acinar cells
brown= serous acinar cells

Question 9

Two locations in which we see a lot of minor salivary glands:

Answer 9

palate & retromolar pad area

Question 10

-minor salivary gland
-circumvalate papillae
-serous acinar

Answer 10

Glands of von Ebner

Question 11

-minor salivary gland
-foliate papillae
-mucous acinar

Answer 11

Glands of Weber

Question 12

-minor salivary gland
-anterior ventral
-mucuos acinar

Answer 12

Glands of Blandin and Nunn

Question 13

Disruption in the ductal system that causes mucous to get trapped inside the connective tissue forming a little balloon or bubble:

Answer 13

mucocele (mucous extravasation reaction)

Question 14

The patient has a history of trauma (biting their lip) resulting in the bluish abnormality, what is the likely diagnosis?

Answer 14

mucocele

Question 15

This is a mucocele occurring on the bottom side of the tongue, what glands are involved?

Answer 15

Glands of blandin and Nunn

Question 16

What can be seen in this histological slide? Pt experienced trauma prior to coming in.

Answer 16

Mucocele (Granulation tissue trying to wall off the mucocele)

Question 17

Common place to find superficial mucoceles:

Answer 17

palate

Question 18

What can be seen in this image?

Answer 18

superficial mucoceles

Question 19

Special type of mucocele associated with the sublingual gland:

Answer 19

ranula

Question 20

When mucin discescts through the mylohyoid muscle presenting as a neck mass:

Answer 20

plunging ranula

Question 21

Mucin that gets trapped inside the salivary ductal system, resulting in the mucin to calcify:

Answer 21

Sialolith (salivary stone)

Question 22

The ductal system that is most commonly affected by sialoliths:

Answer 22

Wharton’s gland

Question 23

Patient comes in complaining of episodic swelling particularly around meal times, and experiences pain due to this- this is a sign of:

Answer 23

A sialolith

(no way for saliva to flow through ductal system because its blocked by a stone resulting in swelling)

Question 24

Patient presents with this and you note it is very hard upon palpation. What is the diagnosis? What gland is this associated with?

Answer 24

Sialolith- Wharton’s duct

Question 25

What type of radiograph would you order if you suspect a sialolith in Wharton’s duct?

Answer 25

Occlusal radiograph

Question 26

Necrotizing sialometaplasia can be described as:

Answer 26

A completely reactive condition

Question 27

Your patient comes in and states “a piece of the roof of their mouth plopped out” with only this info, what would be your diagnosis?

Answer 27

necrotizing sialometaplasia

Question 28

Patient comes in with B/L areas of ulceration on the roof their mouth, what is the diagnosis?

Answer 28

necrotizing sialometaplasia

Question 29

Histologically appears as if the epithelium is pinching off at the surface going into the connective tissue, but is NOT cancerous (pseudoepitheliomatous hyperplasia)

Answer 29

necrotizing sialometaplasia

Question 30

• Pseudoepitheliomatous hyperplasia
• Sialometaplasia
• Coagulative necrosis of the glands

Histologically these may all represent:

Answer 30

necrotizing sialometaplasia

Question 31

This histological slide shows squamous metaplasia of the salivary gland tissue, what is this characteristic of?

Answer 31

necrotizing sialometaplasia

Question 32

Your patient comes in with extremely dry mouth & dry eyes, and remembers they were diagnosed with an autoimmune disorder but doesn’t recall which one. What condition do they have and what does this effect?

Answer 32

Sjogren syndrome; salivary gland tissue

Question 33

Sjogren syndrome where there is NOT another diagnosis of an additional autoimmune disease:

Answer 33

Primary

Question 34

Sjogren’s syndrome + additional diagnosis of another autoimmune disease:

Answer 34

Secondary

Question 35

Patient presents with B/L enlargement of the parotid gland. You perform a biopsy and this biopsy comes back as BLEL (benign lympho-epithelial lesion which is also known as mikuliczs disease) what is your diagnosis?

Answer 35

Sjogren syndrome

Question 36

How can you diagnose Sjorgrens syndrome through laboratory values?
List values specific sjogren syndrome, list values nonspecific to sjogrens syndrome:

Answer 36

Specific: Anti-SS-A & Anti-SS-B

Nonspecific: RF & ANA

Question 37

This patient has asymmetrical enlargement of the parotid glands, what is a likely diagnosis?

Answer 37

Sjogren sundrome

Question 39

Anti-SS-a may also be known as:

Anti-ss-B may also be known as:

A these are labarotry values for:

Answer 39

Anti-Ro
Anti-La

Sjögren’s syndrome

Question 40

Whenever you have a systemic disease that affects the major glands this also:

Give an example of when this occurs

Answer 40

Mimics in the minor glands; Sjögren’s syndrome

Question 41

When performing a lower lip biopsy to harvest some cells, you find lymphoid clusters. You also see that the acinar cells have been completely destroyed leaving remnants of the ducts. There is a high number of the clusters and destroyed acinar cells, what is your diagnosis?

Answer 41

Sjogrens sydrome

Question 42

Patient presents with dry mouth & dry eyes, mouth sticks to tongue depressor, rampant caries, diagnosis?

Answer 42

Sjögren’s syndrome