Disease of salivary glands- malignant Flashcards
List malignant salivary gland tumors:
- mucoepidermoid carcinoma
- adenoid cystic carcinoma
- polymorphous low-grade adenocarcinoma
- acinic cell carcinoma
- carcinoma ex-mixed tumor
- adenocarcinoma NOS
-most common malignant salivary gland neoplasm
- middle-aged females
- clinically mistaken for a mucocele
mucoepidermoid carcinoma
What malignant salivary gland neoplasm is clinically mistaken for a mucocele?
Mucoepidermoid carcinoma
Patient presents with some palatal swelling with some redness and a small point of the start of ulceration. It loos very similar to a mucocele, what is the potential diagnosis?
Mucoepidermoid carcinoma
Diagnose what is seen on the lower lip. The patient states that it is painful and you see a small point of ulceration. What is the differential diagnosis for this?
Mucoepidermoid carcinoma
We don’t see a lot of malignant salivary gland neoplasms on the lip, but if we do see one, it is most likely:
mucoepidermoid carcinoma
What malignant tumor presents histologically with:
- mucous producing cells
- epidermoid (squamous) cells
- may be cystic and/or solid
mucoepidermoid carcinoma
Because it is very hard to differentiate between a high grade mucoepidermoid carcinoma and a squamous cell carcinoma, what staining method may be beneficial for diagnosis:
mucicarmine stain
- best recognized salivary gland tumor
- middle-aged females
- slow growing mass
- painful
- malignant
Adenoid cystic carcinoma
Pt presents with a malignant tumor of the tongue. This is not common, what is the most likely diagnosis?
Adenoid cystic carcinoma
What malignant tumor presents histologically with:
-myoepithelial and ductal cells
- perineurial and perivascular invasion (contributes to poor prognosis)
-cribiform pattern
-SWISS CHEESE
Adenoid cystic carcinoma
What contributes to the poor prognosis of adenoid cystic carcinoma?
Perineural & perivascular invasion
- most common malignant minor salivary gland tumor
- middle-aged females
- favors palate
Polymorphous low-grade adenocarcinoma
If we see a tumor of the retromolar pad, it is mostly likely going to be:
malignant (mucoepidermoid carcinoma)
What malignant tumor presents histologically with:
- deceptive uniform appearance
- different growth patterns
- perineural and perivascular invasion
- Indian filing
PLGA
In this histological image we can see this Indian filing pattern due to perivascular invasion. What is the diagnosis?
PLGA
- Parotid gland
- serous acinar differentiation
- middle-aged females
- slow-growing
- low-grade malignancy
acinic cell carcinoma
What malignant tumor presents histologically with:
- well circumscribed
- may be infiltrative
- serous acinar cell (abundant granular basophilic cytoplasm and a round, stained ecentric nucleus)
acinic cell carcinoma
- long standing pleomorphic adenoma
- older adults
- rapid growth
- pain & ulceration
carcinoma ex-pleomorphic adenoma
Your patient initially had the diagnosis of pleomorphic adenoma. They did not get treatment and this condition worsened accompanied by pain and ulceration. Diagnosis?
Carcinoma ex-pleomorphic adenoma
What malignant tumor presents histologically with:
- typical benign mixed tumor
- malignant degeneration
- cellular pleomorphism
- abnormal mitotic activity
- capsular invasion
carcinoma ex-pleomorphic adenoma
- uncommon salivary gland neoplasm
- cannot be classified
- middle- aged females
adenoma carcinoma NOS
