Disease of Salivary Glands- Benign

Question 1

Distribution of salivary gland tumors- label the percentage that tumor presence in these major salivary glands is benign vs. malignant:

1. Parotid:
2. Submandibular:
3. Sublingual:

Answer 1

Parotid:
50% benign
50% maligant

Submandibular:
40% benign
60% malignant

Sublingual
20% benign
80% malignant

Question 2

List in order from least to greater risk for a tumor to be malignant in the following glands:

-Submandibular
-Parotid
-Sublingual

Answer 2

Parotid –> Submandibular –> Sublingual

Question 3

Distribution of salivary gland tumors- label the percentage that tumor presence in these minor salivary glands is benign vs. malignant:

1. Palate
2. Buccal mucosa
3. Upper labial mucosa
4. Lower labial mucosa
5. Tongue
6. Floor of mouth
7. Retromolar pad

Answer 3

1. Palate: 50-50
2. Buccal mucosa: 50-50
3. Upper labial mucosa: 80B-20M
4. Lower labial mucosa: 15B: 85M
5. Tongue- up to 90
6. Floor of mouth- up to 90
7. Retromolar pad up to 90

Question 4

Describe a benign neoplasm:

Answer 4

-slow growth
-movabole
-asymptomatic
-intact mucosa

Question 5

Describe a malignant neoplasm:

Answer 5

-rapid growth
-fixed
-symptomatic
-ulcerated

Question 6

List the benign salivary gland tumors: (5)

Answer 6

1. benign mixed tumor (pleomorphic adenoma)
2. monomorphic adenoma
3. Warthin’s tumor (papillary cyst adenoma lymphomatosum)
4. oncocytoma
5. ductal papillomas

BMWOD

Question 7

• Most common salivary gland neoplasms
• middle-aged female
• painless slow growing mass

Answer 7

Pleomorphic adenoma

Question 8

Pt presents with this painless mass, states that they noticed it awhile ago and it hasn’t gotten much bigger over time- it appears as enlarged tumor of the parotid gland:

Answer 8

Pleomorphic adenoma

Question 9

Patient presents with this enlarged tumor of the palate. She is a middle-aged female and states that this is painless just annoying because it has been like this for a few years, the hole is a biopsy site- diagnose this:

Answer 9

pleomorphic adenoma

Question 10

Pt presents with a tumor of the upper lip, she is middle-aged and states this is painless and has been slow growing- diagnose:

Answer 10

pleomoprhic adenoma

Question 11

The most common type of salivary gland tumor encountered that can be seen in a variety of locations:

Answer 11

Pleomorphic adenoma

Question 12

What tumor presents histologically with:

-variable histology
-mixture of ductal & myoepithelial elements
-encapsulated

Answer 12

Pleomorphic adenoma

Question 13

Pt presents with a salivary gland tumor, states that it is painless & has been around for months. Upon biopsy you note that it is a mixture of ductal & myoepithelial elements & is also encapsulated. Diagnose this:

Answer 13

Pleomorphic adenoma

Question 14

Your pleomorphic adenoma can have some cool histology- this include:

Answer 14

ability to create cartilage or bone

Question 15

• upper lip
• middle-aged females
• painless slow growing mass
• benign

Answer 15

Monomorphic adenoma

Question 16

Benign salivary tumor most likely to be encountered in the upper lip:

Answer 16

monomorphic adenoma

Question 17

Middle-aged female patient presents with slow growing mass on upper lip. She states she is not experiencing pain. Diagnosis?

Answer 17

monomorphic adenoma

MOstly in the upper lip

Question 18

What tumor presents histologically with:

• uniform pattern
• single layered cords of columnar or cuboidal epithelium
• may demonstrate papillary projections
• loose connective tissue stroma with prominent vascularity
• thin fibrous capsule

Answer 18

monomorphic adenoma

Question 19

This image shows the ENTIRE histological slide looking the exact same. Notice the loose connective tissue stroma with prominent vascularity. Diagnosis?

Answer 19

monomorphic adenoma

Question 20

another name for warthin’s tumer:

Answer 20

papillary cystadenoma lymphomatosum

Question 21

2nd most common benign salivary gland neoplasm:

Answer 21

papillary cystademoma lymphomatosum

Question 22

• 2nd most common benign salivary gland neoplasm
• parotid gland
• occurs bilaterally
• middle-aged males
• smoking
• painless slow growing nodular mass

Answer 22

papillary cystadenoma lymphomatosum

Question 23

Middle aged white male patient present with a slow growing mass in the location of the parotid gland, you note that it appears bilaterally. Patient states he does smoke Diagnose:

Answer 23

Papillary cystademoma lymphomatosum

Question 24

What tumor presents histologically with:

• oncocytic ductal epithelium (uniform double rows)
• lymphoid aggregate
• papillary cystic configuration

Answer 24

Papillary cystadenoma lymphomatosum

Question 25

You take a biopsy of a parotid gland tumor and notice these uniform double rows of oncocytic cells that appear to be lining the cystic spaces. What might be a potential diagnosis?

Answer 25

papillary cystademoma lymphomatosum

Question 26

• Rare benign salivary gland neoplasm
• large epithelial oncocytes
• females (8th decade)
• parotid
• painless slow growing mass (multifocal)

Answer 26

Oncocytoma

Question 27

Benign multifocal tumor of the parotid gland seen in 80 year old female:

Answer 27

oncocytoma

Question 28

What tumor presents histologically with:

• large polyhedral cells abundant in granular eosinophilic cytoplasm (lots of mitochondria
• limited stroma (thin fibrovascular septa)
• lymphoid infiltrate

Answer 28

Oncocytoma

(pink & granular_