DISEASES IN THE NERVOUS SYSTEM

Question 1

NS DISEASES

Answer 1

1. major depressive disorder
2. anxiety disorders
   - panic, OCD, PTSD, social phobia, AN, BN
3. psychosis
   - schizophrenia
   - delusion
   - hallucination
   - disorganized thinking
4. epilepsy
   - seizures
5. parkinson’s disease
6. alzheimer’s disease
   - dementia
   - reduction of ach, Increased Glutamate Neurotransmission, Deposition of Amyloid plaques or Neuritic plaques, Aggregation of Neurofibrillary Tangles (NFTs)
7. multiple sclerosis
8. CVA

Question 2

1. Major depressive disorder

Answer 2

↓BNDF ↑BA

• antidepressants, CBT, and psychotherapy

NSG

Question 3

2. Anxiety

Answer 3

↑NE 5HT ↓GABA

• anxiolytics, antidepressants, CBT, and psychotherapy

Question 4

3. psychosis

Answer 4

↓DA ↑5HT

• antipsychotic drugs (typical and atypical)

SCHIZOPHRENIA

Question 5

4. epilepsy

Answer 5

↑glutamate ↓GABA

• antiepileptic drugs

seizures

Question 6

5. parkinson’s disease

Answer 6

↓DA

• carvidopa
• levidopa
• dopaminologic

bradykinesia, rigidity, resting tremor

Question 7

6. alzheimer’s disease

Answer 7

↓Ach ↑glutamate NFT

Ach inhibitors
- tacrine, donepezil, rivastigmine, galantamine
- memantine
- tau-aggression inhibitors

Question 8

7. multiple sclerosis

Answer 8

destroyed myelin sheath

• immunotherapy

Question 9

CVA

Answer 9

clot formation; blocked or raptured artery

• thromnbolytic anticoagulants