diseases and conditions (spring 25) Flashcards
aplastic anemia
serious
bone marrow failure resulting in erythropenia, leukopenia, thrombocytopenia`
folic acid deficiency anemia
inability to produce sufficient RBCs due to lack of folic acid
hemolytic anemia
destruction of RBCs
results in jaundice
iron deficiency anemia
lack of sufficient iron in RBCs
pernicious anemia
chronic progressive anemia in people over 50 from deficient B12 needed for blood cell development
sickle cell anemia
inherited anemia that causes RBCs to become crescent shaped when oxygen is low
acquired immunodeficiency syndrome (AIDS)
infectious disease caused by HIV
destruction of CD4 T cells leading to opportunistic infections
coagulation disorders
any disruption/impairment in the ability to form blood clots/control bleeding
disseminated intravascular coagulation (DIC)
abnormal blood clotting in small vessels
cuts off oxygen supply to distal tissues
results in damage to body organs
hemophilia
congenital hereditary disorder
deficiency in clotting factor 8/9, results in prolonged bleeding
thrombocytopenia
abnormal decrease in platelets from destruction or low production
graft rejection
recipients immune system identifies transplanted graft as foreign
attacks and destroys graft
graft versus host disease (GVHD)
complication after stem cell/BM transplant
transplant produces antibodies against recipients organs
can cause death
hemoglobinopathy
any disorder caused by abnormalities in the hemoglobin molecule
infectious mononucleosis
acute infectious disease caused by EBV
causes fatigue, malaise, sore throat, lymphadenopathy of neck/armpits
in young adults and children
Kaposi sarcoma (KS)
cancer caused by herpes virus 8
affects skin, mucus membrane and can have extensive visceral involvement
lymphedema
swelling in single arm or leg from accumulation of lymph within tissues
caused by obstruction/disease in lymph vessels
lymphoma
any malignancy involving lymphocytes that commonly affect lymph nodes and lymphatic tissue
hodgkin lymphoma
malignancy of B cells in lymph nodes of neck or chest
can spread to nearby lymph nodes, spleen and sometimes BM