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Pedia Blitz > Diseases > Flashcards

Diseases Flashcards

1
Q

What antigen is associated with dermatomyositis

A

HLA Ag DQA1 *0501

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2
Q

Organisms implicated in dermatomyositis

A

Enterovirus (coxsackievirus b)

GABHS

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3
Q

Periorbital violaceous (heliotropic) erythema crossing the nose bridge

A

Dermatomyositis

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4
Q

Severe prognostic sign of dermatomyositis

A

Dysphagia

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5
Q

+ ANA with speckled pattern

A

Dermatomyositis

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6
Q

Localizes the active site of disease in dermatomyositis

A

MRI

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7
Q

Indicates immunologic activation in dermatomyositis

A

Cd19+ B cells

Indicators of inflammation: vWf Ag, neopterin, Cd19+ B cells

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8
Q

A chronic disease characterized by fibrosis affecting the dermis and arteries of the lungs, kidney and GIT

A

Scleroderma

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9
Q

Earliest manifestation of scleroderma

A

Raynaud phenomenon

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10
Q

CREST Syndrome

A

Calcinosis, raynaud phenomenon, esophageal involvement, sclerosis of skin, telangiectasia

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11
Q

Laboratory finding strongly suggestive of scleroderma

A

+ anti scl 70

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12
Q

Fever of kawasaki disease

A

Fever lasting for at least 5 days

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13
Q

Lymphadenopathy of Kawasaki dse

A

Cervical lymphadenopathy > 1.5 cm usually unilateral

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14
Q

Rash of kawasaki dse

A

Primarily truncal, polymorphous but nonvesical

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15
Q

Cause of kawasaki disease

A

Unknown

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16
Q

IgA mediated vasculitis of small vessels

A

HSP

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17
Q

Organs primarily affected in HSP

A

Skin, GIT, kidneys

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18
Q

Mcc of nonthrombocytopenic purpura in children

A

HSP

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19
Q

Hallmark rash of HSP

A

Palpable petechiae or purpura, evolve from red to brown, last from 3-10 days

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20
Q

Skin biopsy: leukocytoclastic angiitis

A

HSP

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21
Q

Renal biospy finding in HSP

A

IgA mesangial deposition

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22
Q

Most common of the pediatric inflammatory myopathies

A

Dermatomyositis

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23
Q

Diagnosis for TEF

A

Inability to pass an NGT or OGT in the nb

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24
Q

Most common type of EA

A

Type A

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25
Q

Most common esophageal disorder of all ages

A

GERD

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26
Q

Foreign body in the esophagus 6mos-3yrs

A

Coins

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27
Q

In asymptomatic px, blunt objects may be observed up to how many hours

A

Up to 24 hours

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28
Q

Liquid alkali

A

Liquefactive necrosis

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29
Q

Acidic agents

A

Coagulation necrosis

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30
Q

Bilious vomiting

A

High intestinal obstruction

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31
Q

Feculent emesis

A

Low intestinal obstruction

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32
Q

Ground glass appearance in the RLQ with trapped air bubbles seen in meconium ileus

A

Intestinal obstruction (meconium ileus)

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33
Q

Mcc of nonbilious vomiting

A

Pyloric stenosis (whites>asians, m>f)

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34
Q

Metabolic derangement in pyloric stenosis

A

Hypochloremic metabolic alkalosis

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35
Q

Pyloric stenosis (pe findings/dx)

A

Firm, movable, olive shaped mass; visible peristaltic wave after feeding

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36
Q

Surgical procedure fir pyloric stenosis

A

Ramstedt pyloromyotomy

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37
Q

Barium: elongated pyloric channel, a bulge of the pyloric muscle into the antrum

A

Shoulder sign (pyloric stenosis)

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38
Q

Streaks of barium in the narrowed channel

A

Double tract sign (pyloric stenosis)

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39
Q

Most frequent congenital GI anomaly

A

Meckel diverticulum

40
Q

Congenital aganglionic megacolon

A

Hirschsprung disease

41
Q

Mcc of lower intestinal obstruction in neonates

A

hirschsprung disease

42
Q

Currarino triad

A

Hirschsprung disease in older px:
Anorectal malformation
Sacral bone abn
Presacral masses

43
Q

Shoulder sign

A

Pyloric stenosis

44
Q

Bird’s beak sign

A

Volvulus

45
Q

Double bubble sign

A

Duodenal atresia

46
Q

Double tract sign

A

Pyloric stenosis

47
Q

Coiled spring sign

A

Intussusception

48
Q

Inverted u sign

A

Volvulus

49
Q

Doughnut or target sign

A

Intussusception

50
Q

Coffee bean sign

A

Volvulus

51
Q

Diarrhea due to the presence of nonabsorbable solutes in the GIT

A

Osmotic diarrhea

52
Q

Diarrhea due to the activation of intracellular mediators like cAMP, cGMP that stimulate active Cl secretion from crypts

A

Secretory

53
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

54
Q

Stool output of infant

A

5-10 g/kg/day

55
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

56
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

57
Q

Intussusception is correlated with what organism

A

Adenovirus

58
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

59
Q

Stool output of infant

A

5-10 g/kg/day

60
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

61
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

62
Q

Intussusception is correlated with what organism

A

Adenovirus

63
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

64
Q

Stool output of infant

A

5-10 g/kg/day

65
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

66
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

67
Q

Intussusception is correlated with what organism

A

Adenovirus

68
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

69
Q

Stool output of infant

A

5-10 g/kg/day

70
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

71
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

72
Q

Intussusception is correlated with what organism

A

Adenovirus

73
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

74
Q

Stool output of infant

A

5-10 g/kg/day

75
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

76
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

77
Q

Intussusception is correlated with what organism

A

Adenovirus

78
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

79
Q

Stool output of infant

A

5-10 g/kg/day

80
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

81
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

82
Q

Intussusception is correlated with what organism

A

Adenovirus

83
Q

How much fluid is handled by the GIT of an infant

A

285 ml/kg/day

84
Q

Stool output of infant

A

5-10 g/kg/day

85
Q

Hormonal studies for chronic diarrhea

A

VIP, gastrin, secretin

86
Q

The most common cause of intestinal obstruction bet 3 mos - 6 yrs

A

Intussusception

87
Q

Intussusception is correlated with what organism

A

Adenovirus

88
Q

Most common pancreatic disorder in children

A

Acute pancreatitis

89
Q

First clinical evidence of HBV infection

A

Elevation of ALT (6-7 wks p exposure)

90
Q

Most valuable single serologic marker of acute HBV infection

A

Anti HBcAg

91
Q

Marker of active viral replication

A

HBeAg

92
Q

First serologic marker to appear

A

HBsAg (coincides with onset of sx)

93
Q

Immunity after immunization

A

Anti HBs

94
Q

Chronic HBV infection

A

Anti HBc

95
Q

Acute or recent HBV infections

A

IgM anti HBc

96
Q

Hematuria

A

> 5 rbcs/hpf (centrifuged)

Pedia Blitz (16 decks)

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