Diseases 2

Question 1

Compression of left renal vein

Answer 1

Nutcracker syndrome

Question 2

Normal spec gr of urine

Answer 2

1.015 - 1.025

Question 3

Persistent hematuria

Answer 3

3 urinalysis every month with RBCs in the urine

Question 4

Severe flank pain radiating to the groin

Answer 4

Renal colic from calculi

Question 5

Drugs that can cause hematuria

Answer 5

ASA
NSAIDS
Penicillin
Cyclophosphamide
Topimarate

Question 6

Latency period for post strep GN

Answer 6

1-2 wks after throat infection

3-6 wks after pyoderma

Question 7

Laboratory to test carrier state

Answer 7

+ ASO throat culture

Question 8

Confirms recent strep infection

Answer 8

Rising ab titer to strep antigen

Question 9

Best single Ab titer to document skin infection

Answer 9

DNAse B antigen

Question 10

Most common chronic glomerular disease worldwide

Answer 10

IgA Nephropathy

Question 11

Recommended treatment for PSGN

Answer 11

10 day course of Penicillin (limit spread)

Question 12

Potter facies

Answer 12

Polycystic Kidney Disease:

Low set ears, micrognathia, flat nose, limb defects

Question 13

MCC of acute renal failure in young children

Answer 13

HUS

(Mc in

Question 14

HUS Triad

Answer 14

Microangiopathic hemolytic anemia
Thrombocytopenia
Uremia

Question 15

What drugs could cause HUS

Answer 15

Oral contraceptives
Mitomycin
Cyclosporin
Pyran copolymer

Question 16

Peripheral smear of px with HUS

Answer 16

Helmet cells
Burr cells
Fragmented RBCs

Question 17

Upper limit of normal protein excretion in healthy children

Answer 17

~ 150 mg/day

Question 18

Renal biopsy for proteinuria

Answer 18

Proteinuria > 1 g/day
HPN
Diminished renal function

Question 19

Proteinuria in Nephrotic Syndrome

Answer 19

Heavy proteinuria ( 40 mg / m2/hr )

Question 20

Hypoalbuminemia in Nephrotic Syndrome

Question 21

Hypertension and gross hematuria in nephrotic syndrome

Answer 21

Uncommon

Question 22

Major complication of nephrotic syndrome

Answer 22

Infection

Question 23

Usual causes of spontaneous bacterial peritonitis

Answer 23

Strep pneumoniae

E. coli

Question 24

T cells 1st detected in the thymus at what AOG

Answer 24

7th to 8th week

Question 25

Normal ratio CD4+:CD8+

Answer 25

2:1

Question 26

1st line of defense against neonatal herpes virus infection

Answer 26

NK cells

Question 27

Steroid responsive

Answer 27

Urine trace or negative for protein for 3 consecutive days

Question 28

Steroid resistant

Answer 28

Proteinuria 2+ or greater after 8 weeks of steroid

Question 29

Type of hypersensitivity reaction - syphilis

Answer 29

Type IV

Question 30

Type of hypersensitivity reaction - leprosy

Answer 30

Type IV

Question 31

Defect in bruton's disease

Answer 31

Tyrosine kinase deficiency

Question 32

Most common B cell deficiency

Answer 32

Selective IgA deficiency

Question 33

Only disease that is T cell specific

Answer 33

DiGeorge Syndrome

Question 34

Adenosine deaminase deficiency

Answer 34

SCID

Question 35

Deficiency in NADPH oxidase

Answer 35

CGD

Question 36

Cgd is prone to infection by what organism

Answer 36

Catalase positive organism

Question 37

Granule structural defect

Answer 37

Chediak higashi syndrome

Question 38

Granule enzyme deficiency

Answer 38

Myeloperoxidase deficiency

Question 39

Deficiency in TNF gamma

Answer 39

Job's syndrome

Question 40

Defect in what complement pathway is involved in recurrent meningococcal and gonococcal infection

Answer 40

Both (classical and alternative)