DIS - Vitreous Retinal Traction - Week 8 Flashcards
In what four dieases does the vitreoretinal interface play a role in and what technique is extremely useful in evaluating these diseases?
Vitreomacular traction syndrome Epiretinal membranes Macular holes Schisis -OCT useful for evaluation
What is the pathophysiology of macular oedema (2)?
Due to the breakdown of the blood-retina barrier
Fluid leaks into the retina
List 11 associations or causes of macular oedema.
Diabetic retinopathy Branch retinal vein occlusion Retinitis pigmentosa Chronic uveitis Intracular surgery Epiretinal membrane Choroidal tumours Perifoveal telangiectasis Retinal detachment Idiopathic Latanoprost
What kind of vision loss tends to occur with macular oedema? What happens to vision after the oedema is absorbed?
Mild VA loss, often 6/12 to 6/19
Vision recovers as oedema absorbed
Can macular oedema cause permanent vision loss?
Chronic oedema can
Is pain involved with vision loss in macular oedema?
No
How does the fovea/macula appear with macular oedema (4)?
Indistinct
Thinkened
Loss of foveal reflex
Exudate
What angiography pattern can be indiciative of macular oedema?
Petallic hyperfluorescence
How does macular oedema appear on an OCT scan (2)?
Retinal thickening and fluid accumulation
What is a differential diagnosis for macular oedema?
Retinoschisis
List four possible outcomes/complications of macular oedema.
None -spontaneous absorption Macular hole Epiretinal membrane Outer retinal and RPE atrophy -permanent visiond loss
What is the management of macular oedema (3)?
identify cause
OCT/fluorescein angiography
Treat primary condition
What is the treatment of macular oedema secondary to irvine-gass syndrome or uveitis (3)?
Corticosteroids
NSAIDs
Carbonic anhydrase inhibitors
What is the treatment of macular oedema secondary to diabetes (2)? Comment on the effectiveness.
Anti-VEGF
-good clinicald effectiveness
Steroids
-mixed results, associated with cataract/IOP spike
List two surgical treatment options for macular oedema. List a disease each one is indicated for.
Scatter /grid photocoagulation (diabetic retinoapthy, C/BRVO)
Pars planar vitrectomy (uveitis)
What is an epiretinal membrane and where can it be found? What is it additionally known as (2)?
Avascular, fibrocellular (glial) membranes on the surface of the retina
- cellophane maculopathy
- preretinal fibrosis
Are epiretinal membranes more common in younger or older patients?
Older, >70yoa
List four ocular-related secondary causes of epiretinal membranes.
Posteroir vitreous detachment
Vascular retinopathy
Ocular inflammation
Diabetic retinopathy
List four ocular related iatrogenic causes of epiretinal membranes.
Cataract
Retinal detachment repair
Laser
Cryo
Are there systemic causes of epiretinal membranes? Explain (2).
It is possible
Bilateral in 31% of cases
Unaffected eye of an affected individual has 2.5x greater risk than a single eye of an unaffected individuals