DIS - Macular Diseases II: AMD - Week 1 Flashcards
List the 6 components of an AMD work-up.
Measure visual function Fundus view with mydriasis Colour fundus photopgraphy OCT FAF Can also do OCTa for CNVM
What two things should you look for when doing fundus to assess AMD?
Foveal/macular swelling and CNVM (as well as drusen)
What OCT setting should be used to assess AMD?
Macula cube or single line through fovea (just do both)
What central retinal thickness on OCT should you refer?
> 350 microns
Is early CNVM generally visible on colour fundus photography, BIO, or fundus?
Often noot
How should visual function be measured when assessing AMD?
HC + LC VA, and macular VF
What is better, macular cube scan or line scan at the macula?
Macula cube
What should check on an OCT when assessing AMD?
Check ISe integrity
Is identification of CNVM easy or challenging?
challenging
How does CNVM appear on colour fundus photography?
Grey/pinkish yellow lesiond
What can CNVM lead to? How can this appear on FAF?
RPE detachment (pigment epithelial detachment) -hypo-fluorescent donut
List 5 OCT signs of CNVM. Describe how each appears on the OCT.
Disruption of the ISe -self-explanatory Presence of sub-retinal fluid -dark bands Cystic formation within inner retinal layers -dark bubbles Pigment epithelial detachment -clear internal cf drusen (milky) Increased foveal thickness
What foveal thickness on OCT is an indication of CNVM?
> 100 microns between the eyes or >350 microns
List 5 OCT signs of nascent geographic atrophy. Describe how each appears on the OCT.
Disruption of the ISe -self-explanatory Drusen regression Subsidence of OPL and INL -drops down Hyporeflective wedge outer retina Increased signal below bruchs membrane
What does ISe disruption on OCT indicate?
Advanced disease
Nascent geographic atrophy is visible by OCT by up to how many months before CFP/FA?
12 months
When does geographic atrophy tend to form?
After drusen regression
Describe the order of geographic atrophy development on OCT (6).
Disruption of the ISe Drusen regression Subsidence of OPL and INL Hyporeflective wedge outer retina Increased signal below bruchs membrane Complete loss of OS/RPE -geographic atrophy