Diphenhydramine Flashcards
1
Q
What is the trade name?
A
Benadryl.
2
Q
What is the class?
A
Anti-histamine.
3
Q
What is the MOA?
A
H1 and H2 antagonist, blocking histamine release. By blocking the receptors, bronchoconstriction and capillary dilation is decreased.
Primarily works in the GI tract, blood vessels and respiratory tract.
4
Q
What is the dosage?
A
Allergic reaction: 50mg PO (Elixir) or 1mg/kg IM/SIVP/IO to a single maximum dose of 50mg.
Anaphylaxis : 1mg/kg IM/SIVP/IO to a single dose of 50 MG.
Haloperidol - same
Metoclopramide - 25mg.
5
Q
What are some indications?
A
Allergic reaction
Anaphylaxis
Extrapyrimidal symptoms secondary to the admin of haloperidol or metoclopramide.
6
Q
What are some contraindications?
A
Hypersensitivity to diphenhydrinate or diphenhydramine.
