Digestive system Flashcards
peritoneal relationship of LI
ascending colon, descending colon and rectum are retroperitoneal
appendix, transverse colon, sigmoid colon are intraperitoneal
caecum is variable
distinguishing features of the large intestine
semilunar plicae –> internal mucosal folds that are not complete circular.
haustra –> one haustrum is bordered by two neighbouring semilunar plicae, because tania are shorter than the length of the large intestine giving rise to sacculations
tenia coli –> 3 band like structures compose of segregated outer longitudinal muscular layer
epiploic appendages –> fat filled peritoneum projecting from right and left borders of the free tania. are more common in transverse and sigmoid colon
tenia coli
mesenteric tenia : attached to mesentery
mental ténia : attached to greater momentum
Free tania: is free from any attachment (epiploic appendages attach on its right and left borders)
function of the large intestine
reabsorb water and electrolytes and create solid waste
ascending and transverse = involved in reabsorption of water and electrolytes = processing units
descending and sigmoid colon = involved in storage of faeces = storage units
rectum and anu = involved in elimination of faces = elimination units
blood supply of colon and superior rectum
appendix, caecum, ascending and transverse colon = superior mesenteric artery and vain
descending and sigmoid colon = inferior artery and vein
superior part of the rectum = superior rectal artery and vein
nerve supply of colon
midgut :
SNS = superior mesenteric ganglia and lesser splanchnic nerve
PNS = vagus nerve
hind gut
SNS = inferior mesenteric ganglia and lumbar splanchnic nerve
PNS = pelvic splanchnic nerve
histology of large intestine
goblet cells that produce mucous; helps to transport solid content
few absorptive cells (enterocytes) and villi than SI
has straight glands
Rectum
begins at S3 and is bout 12 cm long
peritoneum covers the anterior and lateral walls of the superior 1/3 of the rectum
remainder of the rectum is retroperitoneal
transverse folds of rectum
support the weight of the rectal content and lessen the urge for defecation
border between the rectum and anal canal
anorectal line (upper level of the pelvic diaphragm
line that divides the upper and lower anal canal
pectinate (dentate) line
upper anal canal
gut derivative (endoderm) and is covered by simple columnar epithelium
lower anal canal
ectodermal derivative, covered by stratified squamous epithelium
bloodd supply of the rectum
superior part of the rectum (hindgut) = superior rectal artery (branch of inferior mesenteric artery)
lower part of the rectum develop from the cloaca = middle and inferior rectal arteries (branches of bilateral internal iliac arteries
endocrine glands of pancrea
pancreatic islets = islets of langerhans
liver secretion
produces bile and drains the bile via bile duct into the mucousal surface of the duodenum
pancreas secretion
produces digestive pancreatic juice and drains the juice via pancreatic duct into the duodenum
liver function
produces and stores bile, plasma proteins, and anticoagulant substances
is involved in a variety of metabolic activities of nutrients
detoxifies harmful agents
falciform ligament
attaches the liver to the anterior abdominal wall
splits cranially into right and left coronary ligaments
round ligament
previous umbilical vein is located at the caudal margin of falciform ligament
covering of liver
visceral peritoneum = intraperitoneal
coronary ligament of liver
formed at the reflection site of the visceral peritoneum fro the liver to the diaphragm
completely surrounds the bare area
four lobes of the liver
right lobe, left lobe, caudate lobe and quadrate lobe
what separates the caudate and quadrate lobe?
porta hepatis
where is gall bladder located?
between quadrate and right lobe
what is the ports hepatis?
attachment site of the lesser momentum
blood vessels and nerves enter into the liver via ports hepatis
lesser omentum
spans between the liver and the lesser curvature of the stomach (hepatogastric ligament)
spans between the liver and the duodenum (hepatoduodenal ligament
hepatoduodenal ligament
hepatic triad
contains the bile duct, portal vein and hepatic artery proper
fetal circulation of liver
has ductus venosus of umbilical vein and umbilical vein so that umbilical blood can bypass the liver
umbilical vein becomes the ligamentum teres
ductus venous becomes ligamentum venosum
where does liver receive its blood supply from?
portal vein = oxygen poor and nutrient rich from the intestines
hepatic artery proper from cell trunk
= oxygen rich
gall bladder function
stores concentrated bile
has a cystic duct with spiral valve
blood supply to the gall bladder
cystic artery in the cystohepatic triangle of calot
histology of liver
venous blood from portal vein and arterial blood from hepatic artery mix at the liver capillaries (sinusoids)
direction of blood flow and bile flow are inverse
liver lobe
hexagonal shape
functional unit of the liver
separated from other lobules by connective tissue
composed of hepatocyte plates, a central vein and liver sinusoids
perisinusoidal space
(Disse)
portal triads contain a vein, artery and bile duct
kupffer cells (macrophages) are found in liver sinusoids
space between liver cells and sinusoids are filled with blood plasma that has leaked from the sinusoids
contain stellate cells that store fat and vitamin A
Pancreas features
retroperitoneal
pancreatic enzymes
pancreatic juice also contains sodium bicarbonate which neutralised the stomach acid present in chyme
hormones insulin and glucagon regulate blood glucose levels and are secreted into the blood stream to enter hepatic portal system
five parts of pancreas
uncinate process, head, neck, body and tail
pancreatic ducts
major pancreatic duct runs the entire length of pancreas, joins bile duct at major duodenal papilla
accessory pancreatic duct enters the duodenum separately into minor duodenal papillae
histology of the pancrea
acinus = exocrine part
islets of langerhans = endocrine part
origin of pancreas
2 buds
2 pancreatic duct: accessory duct and main duct
blood supply of the pancreas
celiac trunk
- splenic artery and gasproduodenal artery
superior mesenteric artery
- inferior gastroduodenal artery
superior and inferior pancreaticoduodenal veins