Digestive system Flashcards
What is the alimentary tract
the tract from the mouth all the way to the anus
What are the components of the small intestines
duodenum, jejunem and the ileum
What are the components of the large intestines
Caecum, ascending colon, transverse colon, descending colon, sigmoid colon.
What is the route food takes
Oral cavity, pharynx, epiglottis followed by the oesophagus, stomach, duodenum, jejunum, ilium, ascending colon, transverse colon, descending colon, sigmoid colon, rectum then anus.
What is the mucosa membrane
A type of epithelial membrane that produces mucus.
What is the composition of the mucosa membrane
- Epithelial tissue on the outside
- Under that is lamina propina- connective tissue under the epithelial which has blood vessels, nerve cells and macrophages.
- Under that is muscular is mucosa which is a thin muscular layer
What is the submucosa
another connective tissue layer under the muscularis mucosa and before muscularis external
What is the Muscularis externa
a layer of muscle under the submuscosa. It’s made up of two layers, a circular layer and a longitudinal layer on top of the circular layer
what are the layers of mucosa in order
Epithelia, lamina propia, muscularis mucosa, submucosa then musclaris externa
What cells Make up the oral cavity
stratified squamous.
What are true two types of salivary glands
- small, found in the submucosa of the oral cavity and the tongue
- Large, located in:
- sublingual (under the tongue)
- submandibular ( behind the teeth)
- parotid (in the cheeks)
What is sublingual administration route
Drug is placed under the tongue.
Drug is absorbed rapidly and and has higher circulating levels. However not ideal for bad tasing and irritating drugs
What is the buccal administration route
drug is placed on the cheek
What is the oral administration route.
drug is swallowed. Easy and safe but slow absorption and first pass metabolism can reduce bioavailability
What cells make up the gastric mucosa
simple columnar
Properties of the gastric mucosa
has gastric glands which secrete into gastric pits
Where are bile salts stored
In the gallbladder
How are lipids digested and absorbed
- Bile salts produced in the liver and stored in the gallbladder are released into the ilium via the bile duct.
- they emulsify the lipid by reducing surface tensions through lowering intermolecular bonds
- forms miscelles which have a greater surface area for lipase to act on
- lipase converts triglycerides into monoglyceride and fatty acids
- micelles deliver the fatty acids to the epithelium.
- fatty acids can pass through them membrane via diffusion
- er turn them back into fatty acids before the golgi turn them into chylomicrons by adding proteins to them.