Digestion, Absorption, Transport Of Carbs Flashcards

1
Q

Starch

A

Alpha-D-glucose
Alpha-1,4 and alpha-1,6 glycosidic bonds
Amylose and amylopectin
Storage in plants

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2
Q

Glycogen

A

Storage in animals
Alpha-D-glucose
Alpha-1,4 and alpha-1,6 glycosidic bonds

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3
Q

Cellulose

A

Beta-D-glucose
Beta-1,4 bonds
Unbranched

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4
Q

Sucrose

A

Glucose and Fructose
Alpha, beta-1,2 glycosidic bond
Non reducing

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5
Q

Lactose

A

Galactose and Glucose
Beta-1,4 bond
Reducing

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6
Q

Trehalose

A

Glucose and Glucose
Alpha, alpha-1,1
Non reducing

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7
Q

What does digestion do?

A

Turn poly and disaccharides into their monosaccharides

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8
Q

Where is amylase found?

A

Saliva and pancreas

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9
Q

Salivary alpha amylase

A

Hydrolyzes interior alpha 1 4 bonds, breaking down starch and glycogen into maltose, maltotriose, and alpha-dextrins

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10
Q

What does lactase do?

A

Cleave lactose into galactose and glucose

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11
Q

What does trehalase do?

A

Cleave trehalose into 2 glucoses

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12
Q

What does sucrase do?

A

Cleave sucrose into fructose and glucose

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13
Q

What does sucrose isoamylase do?

A

Cleave maltose into 2 glucoses
Sucrase site - hydrolyzes sucrose to glucose and fructose with maltase activity
Isomaltase site - hydrolyzes alpha 1-6 bt glucose residues with maltase activity

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14
Q

What does glucoamylase do?

A

Cleave maltose into 2 glucose

Cleaves at NR end, one glucose molecule at a time

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15
Q

What does isomaltase do?

A

Cleave isomaltose into 2 glucoses

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16
Q

How does fiber get broken down and what does it get broken down into?

A

Colonic bacteria make it more soluble by converting it to gas, short chain fatty acids, and lactase

17
Q

Glycosidase does what?

A

Hydrolyze glycosidic bonds

18
Q

Salivary alpha-amylases do what?

A

Hydrolyze interior alpha 1-4 bonds bt glucose in amylopectin, amylose, and glycogen into smaller entities

19
Q

What happens in the luminal phase?

A

Intestinal epithelial cells produce cholecystokinin (releases pancreatic alpha amylase) and secretin (releases bicarbonate that neutralizes intestinal pH)

20
Q

What happens in membrane phase?

A

Lactose, maltose, sucrose, maltotriose, and alpha dextrins are broken down from the NR end 1 monosaccharide at a time

21
Q

Glycemic index

A

Indicates how fast blood glucose levels rise after consumption

22
Q

What happens in lactose intolerant people’s intestines?

A

Undirected lactose get into large intestine, water is drawn into large intestine, bacteria ferments lactose to lactate and gas, causing symptoms

23
Q

SGLT proteins

A

Sodium dependent transporter
Active transport
Galactose and glucose

24
Q

Major carb constituents in U.S.

A

Starch, sucrose, lactose

25
Q

Glut1

A

RBCs, blood brain barrier

Expressed in cell types with barrier functions

26
Q

Glut2

A

Liver, pancreatic beta cells, contraluminal memb of intestinal cells
Accepts all 3 monosaccharides
Transfers from intestinal lumen to circulation

27
Q

Glut3

A

Brain (neurons)

Transporter in CNS

28
Q

Glut4

A

Adipose tissue, skeletal muscle, heart muscle

Insulin sensitive transporter

29
Q

Glut5

A

Intestinal epithelial cells, sperm
Fructose transporter
Facilitated diffusion

30
Q

Sglt1

A

Intestinal epithelial cells
Glucose and galactose
Active transport

31
Q

Sglt2

A

Kidney

32
Q

Difference between galactose and glucose

A

Galactose has hydroxyl in beta position, glucose has it in the alpha

33
Q

Alpha position

A

Down