digestion Flashcards

1
Q

What are the 5 stages of digestion and where does each one take place?

A

Ingestion: mouth. Digestion: mechanical and chemical breakdown, chewing and movement in stomach. Absorption: uptake nutrients mainly in small intestine. Compaction: absorbing water and consolidating residue into feces, large intestine. Defecation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the difference between mechanical and chemical digestion?

A

Mechanical digestion: movement, physically breakdown food, chewing, increase surface area and exposure area for chemical digestion. Chemical digestion: Hydrolysis reactions that breakdown macromolecules into monomers. Enzymes (usually end in ‘ase’).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which organs belong to the digestive tract? Which are accessory organs?

A

Digestive tract: mouth, pharynx, esophagus, stomach, small intestines, large intestines, rectum. Accessory organs: teeth, tongue, salivary glands, liver, gallbladder, pancreas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the nervous network that controls the digestive system?

A

Enteric system.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the two networks of the enteric nervous system?

A

Submucosal plexus: controls secretion of mucousa and movement of muscularis mucosae. Myenteric plexus: controls peristalsis and contractions of muscularis externa.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the three ways that the digestive tract is regulated?

A

Neural control: Short (myenteric) reflex- stretch or chemical stimulation. Long (Vagovagal) reflex- parasympathetic stimulation (increase) of digestive motility and secretion. Hormone control: (Gastrin, secretin) stimulate digestive tract. Paracrines: secretions stimulate nearby cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the functions of the mouth?

A

Food intake, taste, sensory response to food.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the functions of the cheeks and lips?

A

Retain food, speech, sucking/blowing, suckling.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the function of the tongue?

A

Taste, texture, manipulate food.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the function of the palate?

A

Separate oral cavity from nasal cavity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How are the hard and soft palate different?

A

Hard palate made of bone and has palatine rugae. Soft palate made of skeletal and glandular tissue.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the uvula and what is its function?

A

Conical medial projection at rear of mouth. Retains food in mouth until swallowing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is mastication?

A

Chewing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How many adult teeth? Baby teeth?

A

32 adult: 2 incisors, 1 canine, 2 premolars, 3 molars, top and bottom. 20 kids.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How are cavities formed?

A

Bacteria metabolize sugars and release acids that dissolve enamel.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the components/functions of saliva?

A

Starch digestion: salivary amylase, lingual lipase: fat digestion, IgA cleans teeth, lysozymes inhibit bacterial growth, create bolus, dissolve molecules to stimulate taste.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the difference between intrinsic and extrinsic salivary glands? Where are the extrinsic glands located?

A

Intrinsic salivary glands: small and found amid other oral tissue (lingual, labial, palatine, buccal). Extrinsic salivary glands: larger, located at parotid (anterior to earlobe), submandibular (under and along mandible), sublingual (floor of mouth).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What causes heartburn?

A

Acid reflux into the esophagus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is deglutition?

A

Swallowing. Controlled by swallowing center (pair nuclei in medulla oblongata).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the difference between parasympathetic and sympathetic stimulation of salivary glands?

A

Parasympathetic: glands produce thin, enzyme-rich saliva. Sympathetic: glands produce thicker, more mucous saliva.

21
Q

What are the phases of swallowing?

A

Oral phase: voluntary, tongue collects food and pushes it posteriorly, food collects at epiglottis then slides down into laryngopharynx. Pharyngeal phase: involuntary, breathing suspended, pharyngeal constrictors push bolus down esophagus. Esophageal phase: peristalsis moves bolus into stomach.

22
Q

What is the main function of the stomach?

A

Food storage, mechanically breakdown food, chemical digestion of proteins and fat, form chyme.

23
Q

Know what each cell produces in the gastric glands.

A

Mucous: secrete mucous, found in cardiac and pyloric glands. Regenerative: divide rapidly and produce new cells. Parietal: secrete HCl, intrinsic factor, ghrelin. Chief: secrete gastric lipase and pepsinogen. Enteroendocrine: secrete hormones and paracrine messengers that regulate digestion.

24
Q

What are the functions of HCl?

A

Provide immunity, liquify food into chyme, convert any iron (Fe) into usable form to create hemoglobin. Secreted by parietal cells of gastric glands.

25
What is the function of pepsin?
Breakdown of proteins. Secreted by chief cells of gastric gland. Activated by pepsinogen.
26
What is the function of gastric lipase and lingual lipase?
Gastric lipase: breakdown fats. Secreted by chief cells of gastric gland. Lingual lipase: breakdown fats.
27
What is the function of intrinsic factor?
Absorb vitamin B12 in small intestine. ESSENTIAL!!! Need B12 to synthesize hemoglobin. Secreted by parietal cells of gastric glands.
28
What is the function of vomiting? What causes vomiting?
Protection from absorbing unwanted materials. 'Reverse peristalsis.'
29
How is the stomach and other organs protected from HCl?
Tight junctions: prevent HCl from leaking around other organs. Epithelial replacement: (stomach lining replaced every 3-6 days). Mucous coat: provide alkaline barrier layer to protect epithelial cells.
30
Most ulcers are caused by what bacteria?
H. Pylori. HCl gets through protective barrier and causes holes in epithelial lining.
31
What are the three phases of gastric function?
Cephalic phase: controlled by brain, stomach responds to sight, smell, taste, or thought of food. Gastric phase: controlled by stomach, swallowed food activates gastric activity by stretching the stomach and increasing the pH. Intestinal phase: controlled by small intestine, duodenum responds to arriving chyme and moderates gastric activity via hormones and nervous reflexes.
32
What is the function of the liver?
Secrete bile.
33
What is the function of the gallbladder?
Stores and concentrates bile. Absorbs water and electrolytes.
34
What is the function of bile?
Emulsify fats. Breakdown fats to increase surface area.
35
What are the products of the pancreas?
Sodium bicarbonate, pancreatic amylase, pancreatic lipase, RNA, DNA.
36
What is the function of trypsin and chymotrypsin?
Trypsin creates more trypsin and converts chymotrypsinogen to chymotrypsin.
37
What 3 stimuli cause the release of pancreatic juice and bile?
Acetylcholine (ACH), Cholecystokinin (CCK), Secretin (raise pH).
38
Where does most digestion and nearly all absorption occur?
Small intestine.
39
What are the three regions of the small intestines?
Duodenum, jejunum, ileum.
40
What are the functions of intestinal motility (segmentation)?
1. Mix chyme with intestinal juice, bile, pancreatic juice. 2. Bring chyme in contact with mucosa for digestion and absorption. 3. Move residue through digestive tract toward large intestine.
41
Be able to trace carbohydrate digestion.
Salivary amylase (mouth) (oligosaccharides) -> Pancreatic Amylase (Pancreas) (maltose) -> Lactase, Sucrase, Maltase (Brush border in small intestine) (monosaccharides).
42
What is lactose intolerance?
Missing the lactase enzyme allows lactose to travel into large intestine and be metabolized there, causing gas and inability to reabsorb water -> diarrhea.
43
Be able to trace protein digestion.
Pepsin (stomach) (peptides) -> Trypsin, Chymotrypsin, Carboxypeptidase (Pancreas) (oligopeptides) -> Carboxypeptidase (Pancreas) aminopeptidase, dipeptidase (Brush border in small intestine) (amino acids).
44
Be able to trace lipid digestion.
Lingual lipase (saliva) -> Gastric lipase (stomach) -> Bile (liver) -> Pancreatic lipase (pancreas) -> Emulsification (small intestine).
45
Be able to trace nucleic acid digestion.
Deoxyribonuclease, ribonuclease (pancreas) -> Phosphatase, nucleosidase (brush border in small intestine).
46
What is the function of the large intestine?
Water and electrolyte absorption.
47
What is the function of bacterial flora in the large intestine?
Digest cellulose, pectin, synthesis Vitamin B & K, produce flatus (intestinal gas).
48
What causes diarrhea? Constipation?
Diarrhea = not enough water reabsorbed by large intestine. Constipation = too much water reabsorbed by large intestine.