Differentiation Of Genitalia Flashcards
What happens to the gonads in males?
Medullary cords develop
Cortex regresses
Leydig and Sertoli cells appear
Thick tunica albunginia forms
When do the genitalia begin to differentiate?
At 7 weeks
What happens to the ducts in males?
Presence of MIS causes mullarian duct to degenerate
Presence of testicular testosterone causes wolffian duct to grow into the seminiferous tubules, epididymis, and vas deferens.
What happens to the external genitalia in males?
The presence of DHT causes:
The genital tubercle elongates (forms the glans penis)
The genital folds fuse to form the spongy urethra
The labioscrotal swellings form the scrotum
What happens to the gonads in females?
The medullary cords degenerate
The medulla regresses
The cortex grows to form the ovaries
What happens to the ducts in females?
The wolffian duct degenerates (no testosterone)
The mullarian duct grows to form the Fallopian tubes, uterus, cervix, and upper vagina (no MIS)
What happens to the external genitalia in females?
The genital tubercle become the clitoris
The genital folds do not fuse and become the labia minora
The labioscrotal swelling form the labia majora