Differentiation Of Genitalia Flashcards

0
Q

What happens to the gonads in males?

A

Medullary cords develop
Cortex regresses
Leydig and Sertoli cells appear
Thick tunica albunginia forms

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1
Q

When do the genitalia begin to differentiate?

A

At 7 weeks

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2
Q

What happens to the ducts in males?

A

Presence of MIS causes mullarian duct to degenerate
Presence of testicular testosterone causes wolffian duct to grow into the seminiferous tubules, epididymis, and vas deferens.

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3
Q

What happens to the external genitalia in males?

A

The presence of DHT causes:
The genital tubercle elongates (forms the glans penis)
The genital folds fuse to form the spongy urethra
The labioscrotal swellings form the scrotum

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4
Q

What happens to the gonads in females?

A

The medullary cords degenerate
The medulla regresses
The cortex grows to form the ovaries

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5
Q

What happens to the ducts in females?

A

The wolffian duct degenerates (no testosterone)

The mullarian duct grows to form the Fallopian tubes, uterus, cervix, and upper vagina (no MIS)

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6
Q

What happens to the external genitalia in females?

A

The genital tubercle become the clitoris
The genital folds do not fuse and become the labia minora
The labioscrotal swelling form the labia majora

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