Diarrhoea and Acute Gastrointestinal Illness Flashcards

1
Q

Signs and symptoms AGI

A

Vomiting
Diarrhoea: Acute, watery, bloody(dysentery), severe (6 x a day)
Abdo pain and cramping
Fever

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2
Q

Virus, bacteria and protozoa as a causative agent

Onset; diarrhoea; vomiting; fever/pain; rehydration; antibiotics

A

Virus: Faster(hrs/days); probably; YES; fever, likely pain; yes; no
Bacteria: range; yes; probaby; abdo pain; yes; sometimes
Protozoa: slower; yes; possibly; abdo pain; yes; prob

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3
Q

Viral causes

_______ and ______
____ _____**, _____ diarrhoea, abdo cramps, muscle aches, low grade fever, headaches

good with ________, last about 24-48 hours

A

Rotavirus and norovirus
Nausea and vomiting**, Watery diarrhoea, abdo cramps, muscle aches, low grade fever, headaches

good with rehydration, last about 24-48 hours
Colonise in small intestine

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4
Q

Ways that bacteria cause AGI

A

Colonisation of intestines and toxin production
Invasion of intestinal tissue
Toxin produced in food but not ingested, food poisoning

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5
Q

Bacterial agents that colonise and produce toxins. What causes dysentery

A

Clostridium difficile (nosocomial, from hosp)
Shiga/Vero toxin producing E-coli (STEC/VTEC)*
Shigella Dysenteriae*
Enterotoxigenic E coli
Vibrio cholerae

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6
Q

Bacterial agents that colonise and invade intestinal tissue

A

Campylobacter jejuni
non typhoid salmonella
yersinia enterocolitica
enteroinvasive E coli

May cause blood in faeces, abdo cramping

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7
Q

Bacterial agents that produce toxins in food that we ingest

A

Staph aureus
Clostridium perfringens
bacillus cereus

vomiting likely within 2-7 hours, clear in 1-2 days.

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8
Q

Protozoa information

_____ and ______

______ contaminated by human faeces e.g _____ _______
incubation of 1 week
symptoms 4-6 weeks
diarrhoea, flatulence, foul stools
mostly self limiting, giardia might need _______

A

Giardia and Cryptosporidium

food/water contaminated by human faeces e.g farmer, tramper, pet owner
incubation of 1 week
symptoms 4-6 weeks
diarrhoea, flatulence, foul stools
mostly self limiting, giardia might need metronidazole

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9
Q

New Zealand most common agenst of AGI

Worldwide AGI

A

Campylobacter, Salmonella, Giardia
Most serious, listeria

Diarrhoeal disease really bad, a lot of cholera. Mostly children. E coli, cholera, norovirus an rotavirus

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10
Q

NZ outbreaks (2 or more cases with common source)

A

Norovirus

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11
Q

Sources of AGI

A

Human/animal GI tract/faeces: Faceal oral route direct or indirect
Animals, infected people and carriers
Contaminated food and water

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12
Q

Contaminated food route

means to stop

A

Animal faces- contaminated carcass(can eat these) and fertilised vegetables
These become food items, which we eat and causes the AGI.
Human Faeces can then be transferred to food product

Slaughter, farming practice, cooking, storage, hygiene

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13
Q

Contaminated water route

means to stop

A

Human and animal faeces contaminate water source
Drinking and irrigation water into our food and drink
AGI

Farming and sewerage, supply, more sewerage

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14
Q

AGI risk factors

A

Consume retail food; consme at risk foods (soft cheese listeria); farm animal contact; consume untreated water; faecal matter contact; symptomatic people contact; recreational water; sick animals; overseas travel within incubation period

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15
Q

Stool culture types

note food worke,r would have 3 negative tests to see if clear

sheep blood; maconkey; maconkey with sorbitol; xld; campy; bile esculin; emb

A
  • Sheep blood: grow most pathogens, including listeria that won’t grow elsewhere
  • MacConkey agar with lactose: E coli will ferment lactose, Salmonella, Shigella, yersinia do not
  • Maconkey agar with sorbitol: most E coli ferment sorbitol, STEC do not
  • XLD: slamonella and shigella grow
  • Campy plate: campylobacter
  • bile esculin: klebsiella and enterobacter
  • emb: gram -ve oxidase negative e coli,klebsiella, enterobacter

Antibody or PCR for viral
Antigen test for protozoa

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16
Q

AGI complications

A

Dehydration, bactaraemia (salmonella, campylobacter); haemolytic uremic syndrome (STEC on kidney); Guillan barre and campylobacter; reactive arthritis campy, yersinia

17
Q

AGI treatment

A

Fluid and electrolyte replacement: very important. clean water, sugar and salt
Easily digestible food
Anti-motility drugs? Reduce stool rate but concentrate toxins

18
Q

Antibiotics?

A

usually not required
Not recommend for STEC

Use when: clostridium difficile (vancomycin, metronidazole)
Salmonella/Campylobacter if risk of systemic infection

19
Q

Severe diarrhoea bacteria to have in mind

A

Shigella, campylobacter, salmonella, yersinia, vibrio if rice water stool (possibly seafood), STEC if bloody, C difficile in hosp

20
Q

Do scenarios in book pg 168

A

mhmm