Blood and Blood Products

Question 1

Blood product; component; plasma derivative

Answer 1

Blood product: Any product derived from human blood
Blood component: a blood product manufactured from a single donation or small pool, such as red cells, platelets or fresh frozen plasma
Plasma derivative: blood product made from large pools of plasma

Question 2

HIV, Hepatitis C and B window periods

Answer 2

HIV: 11 days (more like 3/4 weeks?)
Hep B: 7 days
Hep C: 34days

Question 3

Red cells, Platelets and fresh frozen plasma

Shell life; Main clinical indication

Answer 3

Red cells: 35 days; Improve oxygen delivery in cases of anaemia or blood loss
Platelets: 7 days; management and prevention of bleeding of patients
FFP: 2 years; correct abnormal coagulation

Question 4

Hb levels and transfusion

__g/L: May be appropriate to maintain anaemic patients on chronic transfusion regime
>___g/L: Typically not appropriate

Answer 4

<70g/L: Probably transfuse unless no symptoms
70-100g/L: do if having surgery with large blood loss probable, or signs/symptoms of impaired O2 transport
>80g/L: May be appropriate to maintain anaemic patients on chronic transfusion regime
>100g/L: Typically not appropriate

Question 5

Indications for platelet trasfusion

Answer 5

Bone marrow failure, invasive procedure/surgery (ocular, neuro) and platelet function disorder; bleeding; massive haemorrhage

If levels are low

Question 6

FFP use

Answer 6

Replacement of single factors deficiencies
Acute DIC
etc