Diarrhea

Question 1

What are the two leading causes of death from infectious disease world wide?

Answer 1

Pneumonia

Diarrhea

Question 2

What age groups are preferentially affected by infectious disease?

Answer 2

Young children and the elderly

Question 3

What is the leading cause of morbidity and death with diarrhea?

Answer 3

Dehydration

Question 4

What is the most reversible cause of morbidity and death with diarrhea?

Answer 4

Dehydration

Question 5

What sites and pathogens are involved in non-inflammatory diarrhea?

Answer 5

Site: Small intestine
Pathogens: Norwalk, Rotavirus, Giardia, Cholera, ETEC

Question 6

What sites and pathogens are involved in inflammatory diarrhea?

Answer 6

Site: Colon
Pathogens: C. jejuni, Shigella, Salmonella, E. coli 0157:H7, C. difficile, E. histolytica

Question 7

What pathogens produce watery diarrhea?

Answer 7

Vibrio cholerae
Enterotoxigenic E. coli
Rotavirus
Norwalk virus
Guardia lamblia

Question 8

What is the leading cause of acute bacterial diarrhea in the US?

Answer 8

Campylobacter Jejuni

Question 9

What is the predominant cause of nosocomial diarrhea?

Answer 9

C. difficile

Question 10

What are three organisms that cause inflammatory diarrhea?

Answer 10

Campylobacter jejuni
Salmonella
Shigella

Question 11

E coli O157:H7

Answer 11

Causes vast majority of hemorrhagic colitis in US
Illness lasts 2-4 days
Highest rates in young children and elderly
Symptoms may range from asymptomatic infection to hemolytic uremic syndrome and Thrombotic thrombocytopenic purpura.