Diahorrhea Flashcards
How does WHO define diarrhoea?
3 or more loose or liquid stools per day
OR
more frequent passage than is normal for the individual
Faecal weight more than 200g/day
How do we distinguish chronic/acute diarrhoea?
Acute is less than 2 weeks in duration
Chronic more than 4 weeks
What should you ask about regarding diarrhoea?
Frequency Consistency Presence of blood/mucus Associated symptoms - pain - vomiting - fever BO at night? Urgency? Any incontinence? Do the stools flush away - steathorrea as a result of malabsorption typically do not
How do we classify stool?
Bristol stool chart
What are the different mechanisms of diarrhoea?
Secretory e.g. cholera Osmotic e.g. hypolactasia, drugs, malabsorption Exudative e.g. IBD Abnormal Motility e.g. IBS Mixed Overflow
What is dysentery?
Diarrhoea associated with blood
Also fever, abdominal pain and vomiting
Caused by bacteria commonly e.g. shigella, salmonella
Which amoeba can cause dysentery?
Entamoeba histolytica
Need for ‘hot’ stool sample
Straight to the lab
How do you ellicit that is a GI infection causing diarrhoea?
Short history
Precipitating event e.g. food, personal contact or travel
Fever, abdo pain and vom
What is the treatment for GI infection diarrhoea?
AB treatment and rehydration
What are the main features of C. diff diarrhoea?
Can cause pseudomembraneous colitis
Concern in healthcare settings
Associated with AB use
Can lead to sig mortality in elderly
What is the treatment for c. diff diarrhoea?
Rehydration
Oral metronidazole or vancomycin
In resistant cases - FMT
How does malabsorption cause diarrhoea?
Failure to secrete digestive enzymes - pancreatic disease
OR
Failure to absorb through gut wall - mucosal disease
What are the features of malabsorption diarrhoea?
Steatorrhoea
Pale, bulky, offensive stools
Difficult to flush
Weight loss
Lethary
Anorexia
Abdo discomfort and bloating
How do we assess malabsorption in the lab?
Stool sample for fat globules
3 day faecal fat estimation
Look at FBS for B12, Fe, Ferritin
What diseases can cause malabsorption?
Pancreatic Coeliac Crohn's Infective/Post-infective Bacterial overgrowth Biliary obstruction